Detailed information NTG0082957

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: H7679_RS06310
• Genome accession: NZ_AP023392
• Coordinates: 1280784..1283021 (-)
• Length: 745 a.a.
• NCBI ID: WP_024396039.1
• Uniprot ID: -
• Organism: Streptococcus suis strain DAT300
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1275784..1288021

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7679_RS06285 (DAT300_12000)	tmk	1275900..1276538 (-)	639	WP_024412257.1	dTMP kinase	-
H7679_RS06290 (DAT300_12010)	-	1276713..1277579 (+)	867	WP_002935357.1	YitT family protein	-
H7679_RS06295 (DAT300_12020)	-	1277616..1278887 (-)	1272	WP_002935355.1	toxic anion resistance protein	-
H7679_RS06300 (DAT300_12030)	-	1278893..1279720 (-)	828	WP_024396041.1	hypothetical protein	-
H7679_RS06305 (DAT300_12040)	-	1279814..1280470 (-)	657	WP_024396040.1	CBS domain-containing protein	-
H7679_RS11420	-	1280653..1280775 (-)	123	Protein_1207	IS982 family transposase	-
H7679_RS06310 (DAT300_12050)	comEC/celB	1280784..1283021 (-)	2238	WP_024396039.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
H7679_RS06315 (DAT300_12060)	comEA/celA/cilE	1283005..1283667 (-)	663	WP_024396038.1	helix-hairpin-helix domain-containing protein	Machinery gene
H7679_RS06320 (DAT300_12070)	-	1283734..1284480 (-)	747	WP_014735985.1	lysophospholipid acyltransferase family protein	-
H7679_RS06325 (DAT300_12080)	-	1284627..1286072 (+)	1446	WP_184495576.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-
H7679_RS06330 (DAT300_12090)	-	1286487..1287272 (+)	786	WP_014636900.1	ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 745 a.a.
• Molecular weight: 84099.09 Da
• Isoelectric Point: 7.9232

>NTDB_id=82957 H7679_RS06310 WP_024396039.1 1280784..1283021(-) (comEC/celB) [Streptococcus suis strain DAT300]
MSRSIKLPCQPIHLALLAVAVYFAVHSFSLLTIGLLSLVLTVFGVRQGKTVFLKTLPLLALCGLFFGYQKVQWERADQSA
PEQVTTVQVIPDTIDINGDSLSFRGRADGQTYQVFYKLTSQEEQAYFQKLANLVQLEVEAEVSLPAGQRNFKGFDYQAYL
KTQGIYRTVKITVIKKIVPVQSRNVFDWLSSWRRQALVYVKTNFPAPMSHYMTGLLFGDLDSDFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRLGLTKEAVDKLQIPFSLFYAGLTGFSVSVVRSLVQKILGNLGLRKLDNFAVTVFVCLLIL
PRFLLTAGGILTFTYAFLLTVFDFEDLGQVKKVAVESLSISLGILPVLMTYFFAFQPLSILLTFVFSFVFDVLLLPGLSV
IFLLSPIIKITWVNGFFVFLEKAIVWVADLGLRPWILGKPSELVLLLLLVSLFLLYDFHRRKKWLLGLSLVLALLFFITK
HPLENEVTVVDIGQGDSIFLRDMRGRTVLIDVGGRVDFAAKEAWQERSRQANAERTLIPYLHSRGVDRIDSLVLTHTDTD
HVGDVLEVAKQVQIGRIVVSPGSLMVPDFVATLKKINVPVHVVKVGDRLPIFDSYLEVLYPDGTGDGGNNDSIVLYGRLL
ETNFLFTGDLEQGELDLIETYPNLPVDVLKAGHHGSKGSSYPEFLDHIEAKIALISAGENNRYKHPHQETLDRFDSRDIQ
VYRTDQQGAIRFRGWKEWRIETVRR

Nucleotide

• Length: 2238 bp

>NTDB_id=82957 H7679_RS06310 WP_024396039.1 1280784..1283021(-) (comEC/celB) [Streptococcus suis strain DAT300]
ATGTCACGGTCGATTAAGCTCCCCTGCCAGCCCATCCACTTGGCTCTTTTGGCAGTTGCGGTCTACTTTGCAGTCCACTC
TTTTTCCCTGTTGACAATAGGCCTACTCAGTTTGGTGTTAACTGTCTTTGGTGTTCGGCAAGGTAAGACAGTTTTCCTCA
AAACGCTGCCGCTTCTAGCCCTATGTGGCTTGTTTTTCGGCTACCAAAAGGTCCAATGGGAGCGGGCAGACCAGTCAGCC
CCAGAGCAAGTCACAACTGTTCAGGTCATTCCAGATACCATAGACATCAATGGCGACAGCTTGTCTTTTCGTGGTCGGGC
TGACGGACAAACCTATCAGGTTTTCTATAAATTAACCAGTCAGGAGGAGCAGGCTTATTTTCAAAAGCTGGCAAACCTGG
TCCAGCTAGAAGTGGAAGCAGAGGTCAGCCTGCCAGCTGGTCAGCGGAATTTCAAGGGCTTTGACTATCAGGCCTATCTG
AAAACACAGGGCATCTATCGGACAGTCAAGATTACGGTAATCAAGAAGATTGTCCCTGTTCAGTCTAGGAATGTTTTTGA
CTGGTTGTCAAGCTGGCGGAGGCAGGCTTTAGTTTATGTCAAAACCAATTTTCCGGCTCCCATGAGCCACTACATGACAG
GGCTCTTGTTTGGGGACTTGGATAGTGATTTTGACCAGATGAGTGACCTCTATTCCAGTTTGGGTATCATTCATCTCTTT
GCCCTGTCTGGTATGCAGGTGGGCTTTTTCATCGACAAGTTTCGCTGGATTTTGTTGCGTCTGGGCTTGACCAAGGAAGC
CGTAGATAAGTTGCAGATTCCCTTTTCACTTTTTTATGCTGGTTTGACAGGCTTTTCTGTGTCGGTGGTGCGGTCCTTGG
TCCAAAAAATTCTGGGTAATCTAGGCTTGCGGAAGTTGGATAACTTTGCGGTGACAGTCTTTGTCTGTCTGCTGATACTA
CCCCGATTTTTACTGACAGCAGGAGGTATCCTGACCTTTACCTATGCTTTCTTGCTGACGGTCTTTGATTTTGAGGATTT
GGGGCAGGTCAAAAAGGTTGCGGTGGAGAGCCTCAGTATTTCACTGGGAATTTTGCCGGTGCTTATGACCTATTTCTTTG
CCTTCCAGCCTTTGTCTATCCTCTTGACCTTTGTCTTTTCCTTTGTCTTTGATGTCCTGCTCTTGCCAGGTTTGTCGGTC
ATTTTTCTTCTGTCACCAATCATTAAGATTACCTGGGTCAACGGATTTTTTGTCTTCCTGGAAAAGGCCATTGTATGGGT
GGCTGATTTGGGCTTGCGACCGTGGATATTGGGCAAGCCGTCTGAGCTGGTCCTCTTGCTTTTGCTGGTCAGCCTCTTCT
TGCTCTACGATTTCCACAGGAGAAAGAAATGGCTCCTAGGACTAAGCTTGGTCCTCGCTCTGCTATTTTTCATAACCAAA
CACCCGCTGGAAAACGAGGTGACGGTGGTGGATATCGGGCAGGGGGACAGCATCTTTTTGCGGGATATGCGGGGGCGGAC
GGTTCTGATTGATGTGGGCGGTCGGGTCGATTTCGCGGCCAAGGAAGCCTGGCAGGAGCGGTCTCGGCAGGCAAATGCAG
AGCGGACTTTGATTCCCTATCTGCATAGTCGGGGCGTGGATAGGATTGATAGCTTGGTCCTGACACACACCGACACAGAC
CATGTGGGTGATGTGCTGGAAGTGGCGAAGCAGGTGCAAATTGGTCGGATTGTCGTGTCGCCGGGAAGTCTGATGGTGCC
TGACTTTGTAGCAACTCTGAAAAAAATCAATGTTCCTGTCCATGTGGTAAAAGTGGGCGACCGCCTACCAATTTTTGACT
CCTATCTGGAGGTCCTCTATCCAGACGGGACAGGCGACGGTGGCAATAATGACTCCATTGTCCTTTACGGTCGCTTGTTG
GAAACTAACTTTCTCTTTACAGGAGACCTGGAGCAAGGGGAGTTGGACTTGATAGAAACCTATCCCAACCTGCCTGTCGA
TGTCCTCAAAGCCGGTCACCACGGCTCCAAAGGTTCTTCCTATCCTGAATTTTTGGACCATATCGAAGCCAAGATTGCCT
TGATATCTGCTGGAGAAAATAACCGCTACAAGCATCCACACCAAGAAACCTTGGACCGCTTTGATAGTCGAGATATCCAA
GTCTATCGCACAGACCAGCAAGGAGCCATCCGCTTCCGAGGTTGGAAGGAGTGGAGGATTGAAACGGTGAGGAGGTAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (215-461)

• Domain of unknown function (DUF4131) (DUF4131) (29-172)

• Metallo-beta-lactamase superfamily (Lactamase_B) (493-698)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	54.459	99.329	0.541
comEC/celB	Streptococcus mitis NCTC 12261	53.333	98.658	0.526
comEC/celB	Streptococcus pneumoniae TIGR4	52.31	98.792	0.517
comEC/celB	Streptococcus pneumoniae Rx1	52.038	98.792	0.514
comEC/celB	Streptococcus pneumoniae D39	52.038	98.792	0.514
comEC/celB	Streptococcus pneumoniae R6	52.038	98.792	0.514
comEC	Lactococcus lactis subsp. cremoris KW2	49.599	100	0.498