Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   QLQ48_RS12895 Genome accession   NZ_CP124923
Coordinates   2632576..2633874 (+) Length   432 a.a.
NCBI ID   WP_002415025.1    Uniprot ID   -
Organism   Enterococcus faecalis strain EfsC11     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2627576..2638874
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QLQ48_RS12890 (QLQ48_12890) rlmH 2631696..2632175 (-) 480 WP_002355021.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  QLQ48_RS12895 (QLQ48_12895) htrA 2632576..2633874 (+) 1299 WP_002415025.1 trypsin-like peptidase domain-containing protein Regulator
  QLQ48_RS12900 (QLQ48_12900) ytpR 2633921..2634541 (-) 621 WP_002355018.1 YtpR family tRNA-binding protein -
  QLQ48_RS12905 (QLQ48_12905) - 2634752..2635207 (-) 456 WP_282897464.1 universal stress protein -
  QLQ48_RS12910 (QLQ48_12910) - 2635355..2635669 (-) 315 WP_002355015.1 thioredoxin family protein -
  QLQ48_RS12915 (QLQ48_12915) pepA 2635681..2636757 (-) 1077 WP_002355013.1 glutamyl aminopeptidase -
  QLQ48_RS12920 (QLQ48_12920) - 2637064..2637405 (+) 342 WP_002404031.1 PepSY domain-containing protein -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 44845.98 Da        Isoelectric Point: 4.9968

>NTDB_id=829436 QLQ48_RS12895 WP_002415025.1 2632576..2633874(+) (htrA) [Enterococcus faecalis strain EfsC11]
MQRKDVTPNSDKKSLLQKFGIGLAGGLLGGALILGGAYSGIIPTPNGGNNAATTTSTNHGDTKVSNVSYNVSSDVTKAVK
KVQNSVVSIINMQSASNNSSADDPFGGLFGGNEGTQDSSGNNGNDLEAASEGSGVIYKKDGKTAYVVTNNHVVDKAQGLE
VVLSDGTKVKGELVGTDAYTDLAVIKISSDKVDQVAEFGNSSKITVGEPAIAIGSPLGSDYANSVTQGIISSVNRNITNK
NESGETININAIQTDAAINPGNSGGPLINIEGQVIGINSVKIVQSTSQVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPA
LGITMSDLTGISSQQQEQILKIPASVKTGVVVRGVEAATPAEKAGLEKYDVITKVDGQDVSSTTDLQSALYKKKVGDKME
VTYYRGSKEMKATIDLTIDKSALTQQNNRSNQ

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=829436 QLQ48_RS12895 WP_002415025.1 2632576..2633874(+) (htrA) [Enterococcus faecalis strain EfsC11]
ATGCAACGAAAAGATGTTACACCTAATTCAGATAAAAAAAGTTTATTGCAAAAATTTGGGATTGGTTTAGCTGGCGGCTT
ACTTGGTGGCGCTCTTATTCTAGGAGGCGCTTATTCTGGGATTATTCCCACACCCAACGGCGGAAATAATGCGGCGACGA
CGACGTCCACTAATCACGGCGACACAAAAGTCAGCAATGTGAGTTACAATGTTTCTAGCGATGTCACAAAAGCCGTGAAA
AAAGTTCAAAATTCTGTGGTTTCTATCATTAATATGCAAAGTGCTAGCAACAATTCTTCGGCAGATGATCCTTTTGGGGG
ATTGTTCGGTGGGAATGAAGGTACTCAAGACTCTTCCGGCAACAATGGTAACGATTTAGAAGCAGCCAGTGAAGGTAGTG
GGGTTATTTATAAGAAAGATGGTAAAACGGCTTATGTCGTGACAAATAACCACGTCGTAGATAAAGCGCAAGGATTGGAA
GTTGTTTTATCTGATGGTACCAAAGTGAAAGGCGAATTAGTCGGAACCGATGCTTACACGGATTTAGCCGTGATTAAAAT
TTCTTCCGACAAAGTTGATCAAGTCGCTGAGTTTGGGAATTCTAGTAAAATCACAGTCGGTGAGCCTGCTATTGCGATTG
GTTCCCCTCTAGGTTCTGATTATGCTAACTCTGTCACACAAGGAATCATCTCTTCTGTGAATAGAAATATTACCAATAAA
AACGAGTCTGGTGAAACCATCAATATTAATGCCATTCAAACCGATGCTGCCATCAATCCAGGAAACTCCGGTGGTCCACT
AATCAATATTGAAGGACAAGTCATTGGAATTAACTCAGTAAAAATTGTGCAATCAACTAGTCAAGTGAGCGTTGAAGGGA
TGGGCTTTGCCATTCCAAGTAATGACGTAGTCAACATTATCAACCAATTAGAAAAAGATGGTAAAGTGACGCGGCCAGCT
CTCGGGATTACGATGTCTGATTTAACAGGTATCTCTTCACAACAACAAGAACAAATTTTAAAAATTCCAGCTTCTGTAAA
AACTGGCGTAGTGGTTCGTGGCGTTGAAGCAGCGACCCCTGCTGAAAAGGCTGGATTGGAAAAATACGATGTTATCACGA
AAGTTGACGGCCAAGACGTAAGCTCTACTACAGATTTACAAAGCGCGCTTTACAAGAAAAAAGTTGGCGACAAAATGGAA
GTGACTTATTATCGTGGTTCTAAAGAAATGAAAGCAACCATCGATTTAACCATTGATAAATCAGCTTTAACACAACAAAA
TAATCGCAGCAATCAATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(319-416)

Peptidase family M50 (Peptidase_M50)

(9-416)

Trypsin-like peptidase domain (Trypsin_2)

(132-277)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

52.927

94.907

0.502
  htrA Streptococcus mutans UA159

58.356

84.491

0.493
  htrA Streptococcus mitis NCTC 12261

54.865

85.648

0.47
  htrA Streptococcus pneumoniae TIGR4

55.524

81.713

0.454
  htrA Streptococcus pneumoniae Rx1

55.524

81.713

0.454
  htrA Streptococcus pneumoniae D39

55.524

81.713

0.454
  htrA Streptococcus pneumoniae R6

55.524

81.713

0.454