Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   H7677_RS08530 Genome accession   NZ_AP023391
Coordinates   1743997..1744719 (-) Length   240 a.a.
NCBI ID   WP_184493415.1    Uniprot ID   -
Organism   Streptococcus suis strain DAT299     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1738997..1749719
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7677_RS08510 (DAT299_16420) - 1739141..1740367 (-) 1227 WP_269473631.1 cysteine desulfurase -
  H7677_RS08515 (DAT299_16430) sufD 1740369..1741631 (-) 1263 WP_184493411.1 Fe-S cluster assembly protein SufD -
  H7677_RS08520 (DAT299_16440) sufC 1741648..1742421 (-) 774 WP_002938165.1 Fe-S cluster assembly ATPase SufC -
  H7677_RS08525 (DAT299_16450) - 1742828..1744000 (-) 1173 WP_184493413.1 glycosyltransferase family 4 protein -
  H7677_RS08530 (DAT299_16460) mecA 1743997..1744719 (-) 723 WP_184493415.1 adaptor protein MecA Regulator
  H7677_RS08535 (DAT299_16470) - 1744847..1745683 (-) 837 WP_172078967.1 undecaprenyl-diphosphate phosphatase -
  H7677_RS08540 (DAT299_16480) - 1745810..1747375 (+) 1566 WP_013730562.1 ABC transporter substrate-binding protein/permease -
  H7677_RS08545 (DAT299_16490) - 1747368..1748111 (+) 744 WP_012775335.1 amino acid ABC transporter ATP-binding protein -
  H7677_RS08550 (DAT299_16500) - 1748604..1749314 (-) 711 WP_184493417.1 hypothetical protein -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 28028.55 Da        Isoelectric Point: 4.0497

>NTDB_id=82911 H7677_RS08530 WP_184493415.1 1743997..1744719(-) (mecA) [Streptococcus suis strain DAT299]
MKVKQISDSTLKITIKLDDLEERGMELSDFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDRVDIFVTKSDL
DQNLNFDEFTDLSELGDVASMTPDEFFKSLEQTVREKSAPDATAVRHLEEVEQEEEADEEEQERYIYYILEFPTIEDLFT
FVGTVDYPVEESELYKMDGHYYLTVLINVENRSKQYPGYILSRMLEFTNDTRLTRPALQEHGTLMLPLAAIEELRKVPTV

Nucleotide


Download         Length: 723 bp        

>NTDB_id=82911 H7677_RS08530 WP_184493415.1 1743997..1744719(-) (mecA) [Streptococcus suis strain DAT299]
ATGAAAGTAAAGCAAATTAGTGATTCAACCTTGAAAATCACTATAAAATTAGATGATTTGGAAGAGAGAGGAATGGAACT
TTCGGACTTTCTCATTCCGCAAGAAAAGACAGAGGAGTTCTTTTACACTGTTTTGGATGAATTGGATTTACCAATGACTT
TTCGAGAAAGCGGTATGCTGAGTTTTCGTGTGACTCCGAAGCCAGATCGGGTGGACATCTTTGTTACCAAATCTGATTTG
GATCAGAACTTGAATTTTGATGAATTTACAGATTTGTCGGAACTTGGTGATGTCGCAAGTATGACTCCAGATGAGTTTTT
CAAGAGTTTGGAGCAAACCGTTCGTGAGAAAAGCGCACCGGATGCAACAGCCGTTCGGCATTTGGAAGAGGTAGAGCAAG
AGGAAGAAGCAGATGAAGAGGAGCAGGAGCGCTATATTTACTATATTTTGGAATTTCCAACGATAGAGGATCTGTTTACT
TTTGTTGGTACGGTTGATTATCCAGTAGAAGAATCGGAATTATATAAAATGGATGGCCACTACTACTTGACCGTTCTTAT
CAATGTAGAAAATCGTTCCAAGCAGTATCCAGGCTACATTCTCTCACGAATGTTGGAATTTACCAATGATACTAGGTTGA
CCAGACCTGCTTTACAAGAACACGGAACTTTGATGCTTCCGCTTGCGGCAATCGAGGAGCTTAGGAAGGTTCCGACAGTA
TGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

52.049

100

0.529
  mecA Streptococcus pneumoniae D39

52.049

100

0.529
  mecA Streptococcus pneumoniae R6

52.049

100

0.529
  mecA Streptococcus pneumoniae TIGR4

52.049

100

0.529
  mecA Streptococcus mutans UA159

50.41

100

0.513
  mecA Streptococcus thermophilus LMD-9

47.5

100

0.475
  mecA Streptococcus thermophilus LMG 18311

47.083

100

0.471

Multiple sequence alignment