Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   KUN2590_RS01405 Genome accession   NZ_AP023387
Coordinates   261186..261737 (+) Length   183 a.a.
NCBI ID   WP_011106595.1    Uniprot ID   A0A5S4TPS4
Organism   Streptococcus pyogenes strain NIH34     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 256186..266737
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KUN2590_RS01405 (SPNIH34_02240) comX/sigX/comX2/sigX2 261186..261737 (+) 552 WP_011106595.1 sigma-70 family RNA polymerase sigma factor Regulator
  KUN2590_RS01410 (SPNIH34_02250) truA 261924..262673 (+) 750 WP_002995162.1 tRNA pseudouridine(38-40) synthase TruA -
  KUN2590_RS01415 (SPNIH34_02260) - 262663..263427 (+) 765 WP_002982821.1 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase -
  KUN2590_RS01420 (SPNIH34_02270) - 263417..263887 (+) 471 WP_011106596.1 ECF transporter S component -
  KUN2590_RS01425 (SPNIH34_02280) - 263901..264461 (+) 561 WP_002995157.1 TIGR01440 family protein -
  KUN2590_RS01430 (SPNIH34_02290) - 264526..265371 (-) 846 WP_002982833.1 mechanosensitive ion channel family protein -

Sequence

Protein


Download         Length: 183 a.a.        Molecular weight: 22309.13 Da        Isoelectric Point: 10.0375

>NTDB_id=82666 KUN2590_RS01405 WP_011106595.1 261186..261737(+) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain NIH34]
MSCCFFVVLFILGIVKKKRRLKMSIETRAVFEKVKPIILKLKRHYYIQLWDRDDWLQEGHIILLQLLERYPELIEEEERL
YRYFKTKFSSYLKDLLRRQESQKRQFHKLAYEEIGEVAHAIPSRGLWLDDYVAYQEVIASLENQLNSQERMQFQALIRGE
RFKGRRALLRKISPYFKEFAQQL

Nucleotide


Download         Length: 552 bp        

>NTDB_id=82666 KUN2590_RS01405 WP_011106595.1 261186..261737(+) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain NIH34]
ATGTCCTGTTGTTTTTTTGTGGTTCTCTTTATACTAGGGATAGTTAAAAAGAAAAGGAGACTCAAAATGTCGATAGAGAC
AAGAGCAGTGTTTGAAAAAGTTAAGCCCATTATTTTGAAATTAAAGCGACACTATTATATTCAATTGTGGGATAGAGATG
ACTGGTTACAAGAAGGACATATTATTTTATTACAGTTACTAGAAAGGTACCCAGAGTTAATTGAGGAAGAAGAGCGTTTA
TATCGCTATTTTAAAACAAAATTTTCATCTTATTTGAAAGATTTATTACGCCGTCAAGAAAGTCAAAAGCGTCAGTTCCA
TAAGTTAGCATATGAAGAGATAGGGGAGGTTGCACATGCCATTCCATCGAGAGGGTTATGGCTAGACGACTATGTGGCTT
ATCAAGAGGTAATAGCTAGCTTAGAGAACCAATTAAATTCGCAAGAGCGTATGCAGTTTCAAGCACTTATCAGGGGCGAA
CGTTTCAAGGGAAGACGTGCTCTACTTAGGAAGATCAGTCCCTATTTTAAGGAATTTGCACAGCAGTTGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5S4TPS4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.