Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   QJV49_RS06490 Genome accession   NZ_CP124538
Coordinates   1287887..1289113 (+) Length   408 a.a.
NCBI ID   WP_225512492.1    Uniprot ID   A0AA49EYL4
Organism   Lactococcus sp. NH2-7C     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1282887..1294113
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QJV49_RS06465 (QJV49_06465) - 1283981..1284784 (-) 804 WP_225512495.1 phosphatidate cytidylyltransferase -
  QJV49_RS06470 (QJV49_06470) - 1284784..1285518 (-) 735 WP_225512494.1 isoprenyl transferase -
  QJV49_RS06475 (QJV49_06475) yajC 1285883..1286215 (-) 333 WP_003130588.1 preprotein translocase subunit YajC -
  QJV49_RS06480 (QJV49_06480) - 1286310..1287008 (-) 699 WP_225512493.1 DNA alkylation repair protein -
  QJV49_RS06485 (QJV49_06485) rlmH 1287032..1287511 (-) 480 WP_003130585.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  QJV49_RS06490 (QJV49_06490) htrA 1287887..1289113 (+) 1227 WP_225512492.1 S1C family serine protease Regulator
  QJV49_RS06495 (QJV49_06495) - 1289239..1290237 (+) 999 WP_225512491.1 glycosyltransferase family 4 protein -
  QJV49_RS06500 (QJV49_06500) - 1290363..1291703 (+) 1341 WP_225512490.1 glycosyltransferase family 4 protein -
  QJV49_RS06505 (QJV49_06505) - 1291811..1292035 (+) 225 WP_003130579.1 YkuJ family protein -
  QJV49_RS06510 (QJV49_06510) - 1292170..1293171 (+) 1002 WP_225512489.1 hypothetical protein -
  QJV49_RS06515 (QJV49_06515) - 1293212..1293964 (-) 753 WP_225512488.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 41650.97 Da        Isoelectric Point: 4.8579

>NTDB_id=826338 QJV49_RS06490 WP_225512492.1 1287887..1289113(+) (htrA) [Lactococcus sp. NH2-7C]
MAKANIGKLLLTGVVGGAIALGGSAIYQSTTNQLGNNSRSNTTSTKVSDVSVNVNTDVTSAIKKVSNSVVSVMNYQKDNS
QSSDFSSIFGGNSGSSSSTDGLQLSSEGSGVIYKKSGGDAYVVTNYHVIAGNSSLDVLLSGGQKVKASVVGYDEYTDLAV
LKISSEHVKDVATFADSSKLTIGEPAIAVGSPLGSQFANTATEGILSATSRQVTLTQENGQTTNINAIQTDAAINPGNSG
GALINIEGQVIGITQSKITTTEDGSTSVEGLGFAIPSNDVVNIINKLEADGKISRPALGIRMVDLSQLSTNDSSQLKLPS
SVTGGVVVYSVQSGLPAASAGLKAGDVITKVGDTAVTSSTDLQSALYSHNINDTVKVTYYRDGKSNTADVKLSKSTSDLE
TSSSSSSN

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=826338 QJV49_RS06490 WP_225512492.1 1287887..1289113(+) (htrA) [Lactococcus sp. NH2-7C]
ATGGCAAAAGCTAATATAGGAAAATTGCTATTAACAGGTGTCGTGGGCGGAGCCATCGCACTTGGAGGAAGTGCAATCTA
CCAAAGCACTACAAATCAACTAGGGAACAATAGTCGTTCTAACACCACAAGTACCAAGGTTAGTGATGTTTCGGTAAATG
TCAATACCGATGTTACCTCTGCAATTAAAAAAGTTTCAAATTCTGTCGTTTCTGTTATGAATTATCAAAAAGATAACTCA
CAAAGTAGTGATTTCAGTTCAATTTTTGGCGGAAATAGTGGTTCAAGTTCATCAACTGATGGCTTACAGCTTTCTAGTGA
AGGCTCTGGTGTGATCTACAAGAAATCTGGTGGAGATGCCTACGTTGTAACTAATTACCACGTAATTGCTGGTAATAGCT
CACTTGATGTTCTGCTTTCTGGTGGACAAAAAGTCAAAGCTTCTGTAGTTGGTTATGATGAATACACAGACCTTGCTGTT
CTTAAAATCAGTTCTGAACATGTCAAAGATGTGGCGACATTCGCTGATTCTAGTAAATTAACAATTGGTGAACCTGCCAT
TGCCGTTGGCTCACCTTTAGGTAGTCAATTTGCTAACACCGCAACTGAAGGAATTTTATCTGCAACAAGCCGTCAAGTGA
CTTTGACCCAAGAAAATGGTCAAACAACTAATATCAATGCAATACAAACAGATGCTGCCATTAATCCTGGTAACTCTGGA
GGTGCTTTGATTAATATTGAAGGACAAGTTATTGGAATTACTCAAAGTAAAATTACAACCACTGAAGATGGTTCGACTTC
TGTCGAAGGTTTAGGATTTGCTATCCCTTCTAATGATGTTGTAAATATTATTAATAAACTTGAAGCCGATGGTAAAATTT
CACGTCCTGCTTTGGGTATTCGAATGGTTGACCTTTCACAATTATCAACAAATGACAGTTCACAATTGAAATTACCAAGT
AGTGTAACAGGTGGGGTTGTCGTTTACTCCGTCCAATCTGGCCTTCCTGCTGCCTCAGCTGGTTTGAAAGCCGGGGATGT
AATTACAAAGGTTGGCGATACGGCAGTAACTTCTTCAACAGACTTGCAAAGTGCTCTTTACTCACATAATATCAATGATA
CAGTAAAAGTTACTTATTATCGTGATGGTAAATCAAATACAGCAGATGTTAAACTTTCTAAATCAACCAGTGATTTAGAA
ACAAGCAGTTCATCTTCTTCTAATTAA

Domains

Predicted by InterproScan.

Peptidase family M50 (Peptidase_M50)

(223-396)

Trypsin-like peptidase domain (Trypsin_2)

(108-253)

PDZ domain (PDZ_2)

(296-392)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mitis NCTC 12261

56.283

93.627

0.527
  htrA Streptococcus gordonii str. Challis substr. CH1

53.453

95.833

0.512
  htrA Streptococcus pneumoniae D39

58.309

84.069

0.49
  htrA Streptococcus pneumoniae TIGR4

58.309

84.069

0.49
  htrA Streptococcus pneumoniae R6

58.309

84.069

0.49
  htrA Streptococcus pneumoniae Rx1

58.309

84.069

0.49
  htrA Streptococcus mutans UA159

53.134

89.951

0.478