Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   R8635_RS04710 Genome accession   NZ_AP026924
Coordinates   889604..890152 (+) Length   182 a.a.
NCBI ID   WP_229294014.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700063     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 884604..895152
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8635_RS04675 (PC0062_09320) rplJ 885637..886137 (+) 501 WP_001287278.1 50S ribosomal protein L10 -
  R8635_RS04680 (PC0062_09330) rplL 886213..886581 (+) 369 WP_001196960.1 50S ribosomal protein L7/L12 -
  R8635_RS04685 (PC0062_09340) - 886768..887355 (+) 588 WP_000821280.1 CPBP family intramembrane glutamic endopeptidase -
  R8635_RS04690 (PC0062_09350) - 887557..887694 (+) 138 WP_000718654.1 hypothetical protein -
  R8635_RS04695 (PC0062_09370) - 888490..888708 (+) 219 Protein_931 hypothetical protein -
  R8635_RS04700 - 889008..889295 (-) 288 Protein_932 transposase -
  R8635_RS04705 (PC0062_09380) - 889294..889557 (+) 264 Protein_933 transposase -
  R8635_RS04710 (PC0062_09390) comA 889604..890152 (+) 549 WP_229294014.1 ATP-binding cassette domain-containing protein Regulator
  R8635_RS04715 (PC0062_09400) - 890165..890335 (+) 171 WP_000711943.1 hypothetical protein -
  R8635_RS04720 (PC0062_09410) gdhA 890831..892177 (-) 1347 WP_000199575.1 NADP-specific glutamate dehydrogenase -
  R8635_RS04725 - 892517..893183 (+) 667 Protein_937 winged helix-turn-helix domain-containing protein -
  R8635_RS04730 - 893153..893824 (+) 672 Protein_938 Dyp-type peroxidase domain-containing protein -
  R8635_RS04735 (PC0062_09450) - 893910..894398 (+) 489 WP_001835775.1 hypothetical protein -
  R8635_RS04740 (PC0062_09460) - 894455..894697 (-) 243 WP_000710764.1 type B 50S ribosomal protein L31 -

Sequence

Protein


Download         Length: 182 a.a.        Molecular weight: 20317.58 Da        Isoelectric Point: 7.8649

>NTDB_id=82541 R8635_RS04710 WP_229294014.1 889604..890152(+) (comA) [Streptococcus pneumoniae strain PZ900700063]
MDTGKVLFDGVNINQIDKKILSQNLGVVPQDSFLLNRSILDNITLKHEVTSQKIEEVCKAVQIYDEIMAMPMKFNTIISE
MGSNISGGQRQRIALARALINNPSIVILDEATSALDTINEERITKYIKSQGCTQIIVAHRLSTIKDADIIVVMKGGKIVE
SGNHKYLMDLGGEYYSLYTKRK

Nucleotide


Download         Length: 549 bp        

>NTDB_id=82541 R8635_RS04710 WP_229294014.1 889604..890152(+) (comA) [Streptococcus pneumoniae strain PZ900700063]
ATTGATACAGGAAAAGTTTTATTTGATGGTGTAAATATTAATCAAATAGATAAAAAAATATTAAGTCAAAATTTAGGAGT
AGTTCCACAGGATTCGTTTTTATTGAACAGAAGTATTCTTGATAACATAACTTTAAAGCACGAAGTTACTTCACAAAAGA
TAGAGGAAGTTTGTAAAGCAGTTCAAATCTATGATGAAATCATGGCTATGCCGATGAAATTTAATACTATCATCTCAGAG
ATGGGTTCAAATATTTCAGGTGGTCAAAGACAACGGATAGCACTGGCACGTGCATTAATAAATAATCCTAGTATTGTAAT
TTTAGATGAAGCAACTAGTGCTTTAGACACTATTAATGAGGAAAGAATAACAAAGTATATAAAAAGTCAGGGCTGTACTC
AAATAATTGTAGCTCATAGATTGTCAACGATTAAGGATGCGGATATTATTGTTGTAATGAAAGGTGGTAAGATTGTTGAG
TCAGGAAATCATAAGTACTTAATGGATCTTGGTGGAGAGTACTACAGCTTATATACAAAAAGGAAATGA

Domains

Predicted by InterProScan.

ABC transporter (ABC_tran)

(2-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

43.75

96.703

0.423
  comA Streptococcus gordonii str. Challis substr. CH1

43.258

97.802

0.423
  comA Streptococcus mitis SK321

43.182

96.703

0.418
  comA/nlmT Streptococcus mutans UA159

42.222

98.901

0.418
  comA Streptococcus pneumoniae R6

42.614

96.703

0.412
  comA Streptococcus pneumoniae Rx1

42.614

96.703

0.412
  comA Streptococcus pneumoniae D39

42.614

96.703

0.412
  comA Streptococcus pneumoniae TIGR4

41.477

96.703

0.401
  rcrQ Streptococcus mutans UA159

36.216

100

0.368

Multiple sequence alignment