Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   SE146_RS00645 Genome accession   NZ_CP138339
Coordinates   137359..137640 (+) Length   93 a.a.
NCBI ID   WP_003696701.1    Uniprot ID   A0A0H4IVZ5
Organism   Neisseria gonorrhoeae strain TH2288     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 132359..142640
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SE146_RS00610 (SE146_00610) - 132674..132901 (+) 228 WP_003694773.1 hypothetical protein -
  SE146_RS00615 (SE146_00615) - 132894..133247 (+) 354 WP_003704890.1 hypothetical protein -
  SE146_RS00620 (SE146_00620) - 133308..134582 (+) 1275 WP_050169376.1 HlyD family secretion protein -
  SE146_RS00625 (SE146_00625) - 134767..135114 (+) 348 WP_003687399.1 hypothetical protein -
  SE146_RS00630 (SE146_00630) - 135128..135343 (+) 216 WP_003687400.1 hypothetical protein -
  SE146_RS00635 (SE146_00635) - 135445..137163 (+) 1719 Protein_122 peptidase domain-containing ABC transporter -
  SE146_RS00640 (SE146_00640) - 137164..137280 (-) 117 Protein_123 IS5/IS1182 family transposase -
  SE146_RS00645 (SE146_00645) comA 137359..137640 (+) 282 WP_003696701.1 ATP-binding cassette domain-containing protein Regulator
  SE146_RS00650 (SE146_00650) - 137661..138887 (-) 1227 WP_003690589.1 YihY family inner membrane protein -
  SE146_RS00655 (SE146_00655) - 138986..139172 (+) 187 Protein_126 NAD(P)H-quinone oxidoreductase -
  SE146_RS00660 (SE146_00660) queC 139376..140035 (+) 660 WP_047919051.1 7-cyano-7-deazaguanine synthase QueC -
  SE146_RS00665 (SE146_00665) - 140063..140578 (+) 516 WP_003687408.1 DUF1543 domain-containing protein -
  SE146_RS00670 (SE146_00670) queD 140666..141088 (+) 423 WP_003687410.1 6-carboxytetrahydropterin synthase QueD -
  SE146_RS00675 (SE146_00675) - 141354..141722 (+) 369 WP_003687411.1 DUF1304 domain-containing protein -
  SE146_RS00680 (SE146_00680) - 141719..142357 (+) 639 WP_003687414.1 7-carboxy-7-deazaguanine synthase QueE -

Sequence

Protein


Download         Length: 93 a.a.        Molecular weight: 10117.78 Da        Isoelectric Point: 6.4598

>NTDB_id=824765 SE146_RS00645 WP_003696701.1 137359..137640(+) (comA) [Neisseria gonorrhoeae strain TH2288]
MIREEISAMPMGYETLIGDMGSALSGGQKQRIVLARALYCEPKILFLDEAASHLDIANEKAVNANLNGLSIIKIMAAHRK
ETVESADRKMSLG

Nucleotide


Download         Length: 282 bp        

>NTDB_id=824765 SE146_RS00645 WP_003696701.1 137359..137640(+) (comA) [Neisseria gonorrhoeae strain TH2288]
ATGATTCGCGAAGAAATCTCCGCCATGCCTATGGGCTATGAAACCTTGATCGGCGATATGGGCAGCGCACTGTCAGGCGG
ACAAAAACAACGTATCGTATTGGCGCGGGCCTTATATTGCGAACCGAAAATCCTATTTTTAGATGAAGCGGCCAGTCATT
TGGATATTGCCAATGAAAAAGCAGTCAATGCAAACTTGAATGGCTTGTCTATTATAAAAATTATGGCGGCACACAGAAAG
GAAACGGTGGAATCAGCAGATAGGAAAATGTCTTTAGGATAA

Domains

Predicted by InterProScan.

ABC transporter (ABC_tran)

(14-51)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H4IVZ5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis SK321

46.154

97.849

0.452
  comA Streptococcus mitis NCTC 12261

45.055

97.849

0.441
  comA Streptococcus pneumoniae TIGR4

45.055

97.849

0.441
  comA Streptococcus pneumoniae Rx1

45.055

97.849

0.441
  comA Streptococcus pneumoniae R6

45.055

97.849

0.441
  comA Streptococcus pneumoniae D39

45.055

97.849

0.441
  comA/nlmT Streptococcus mutans UA159

47.126

93.548

0.441
  comA Streptococcus gordonii str. Challis substr. CH1

43.956

97.849

0.43