Detailed information NTG0823389

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: QGO80_RS05285
• Genome accession: NZ_CP123969
• Coordinates: 1033877..1034557 (-)
• Length: 226 a.a.
• NCBI ID: WP_000590620.1
• Uniprot ID: A0AAV3JNX7
• Organism: Streptococcus agalactiae strain CS2108
• Function: repress competence development; post-transcriptional repression of CSP production (predicted from homology) Competence regulation

Genomic Context

Location: 1028877..1039557

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QGO80_RS05260 (QGO80_05260)	-	1029399..1029833 (-)	435	Protein_954	DUF3307 domain-containing protein	-
QGO80_RS05265 (QGO80_05265)	-	1029823..1030509 (-)	687	WP_000280308.1	SatD family protein	-
QGO80_RS05270 (QGO80_05270)	ffh	1030576..1032141 (-)	1566	WP_000863589.1	signal recognition particle protein	-
QGO80_RS05275 (QGO80_05275)	-	1032159..1032491 (-)	333	WP_000402075.1	putative DNA-binding protein	-
QGO80_RS05280 (QGO80_05280)	ciaH	1032580..1033893 (-)	1314	WP_000042576.1	HAMP domain-containing sensor histidine kinase	Regulator
QGO80_RS05285 (QGO80_05285)	ciaR	1033877..1034557 (-)	681	WP_000590620.1	response regulator transcription factor	Regulator
QGO80_RS05290 (QGO80_05290)	-	1034719..1036069 (-)	1351	Protein_960	ERAP1-like C-terminal domain-containing protein	-
QGO80_RS05295 (QGO80_05295)	phoU	1036215..1036868 (-)	654	WP_000946330.1	phosphate signaling complex protein PhoU	-
QGO80_RS05300 (QGO80_05300)	pstB	1036902..1037660 (-)	759	WP_000193363.1	phosphate ABC transporter ATP-binding protein PstB	-
QGO80_RS05305 (QGO80_05305)	pstB	1037672..1038475 (-)	804	WP_000852851.1	phosphate ABC transporter ATP-binding protein PstB	-
QGO80_RS05310 (QGO80_05310)	pstA	1038487..1039374 (-)	888	WP_000992189.1	phosphate ABC transporter permease PstA	-

Sequence

Protein

• Length: 226 a.a.
• Molecular weight: 25852.63 Da
• Isoelectric Point: 4.2507

>NTDB_id=823389 QGO80_RS05285 WP_000590620.1 1033877..1034557(-) (ciaR) [Streptococcus agalactiae strain CS2108]
MIKILLIEDDLSLSNSVFDFLDDFADVMQIFDGEEGLYEAESGVYDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTA
KESIDDKGQGFDLGADDYLTKPFYLEELKMRIQALLKRSGKFNDNSLIYGDIRVDMSTNSTFVNQTEVELLGKEFDLLVY
FLQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKVRKKLKGTLFSENLQTLRSVGYILKHVETD

Nucleotide

• Length: 681 bp

>NTDB_id=823389 QGO80_RS05285 WP_000590620.1 1033877..1034557(-) (ciaR) [Streptococcus agalactiae strain CS2108]
ATGATAAAAATTTTATTAATTGAAGATGACTTGAGTCTTTCCAATTCCGTTTTTGATTTCCTTGATGACTTTGCCGATGT
CATGCAAATTTTTGATGGAGAAGAGGGTCTTTACGAAGCCGAAAGTGGAGTCTATGATCTGATTCTTCTAGATCTCATGT
TACCTGAAAAAAACGGCTTCCAAGTGTTGAAAGAGCTACGTGAAAAAGGTATTACAACCCCTGTATTAATAATGACCGCT
AAAGAAAGCATTGATGATAAGGGACAAGGTTTCGACTTAGGTGCTGATGATTATCTAACAAAACCTTTTTACCTAGAAGA
ACTAAAAATGCGAATTCAGGCTCTTTTAAAGCGTTCTGGAAAATTTAATGATAACAGCCTAATTTATGGTGATATTCGCG
TAGACATGTCTACTAACTCAACCTTTGTTAATCAAACAGAAGTTGAGCTCTTAGGTAAAGAGTTTGATCTTTTAGTCTAT
TTCCTTCAAAATCAAAATGTTATCTTACCGAAATCTCAAATCTTTGATCGTATTTGGGGATTTGATAGTGATACAACGAT
TTCAGTTGTAGAAGTCTATGTCTCTAAGGTTCGGAAAAAATTAAAAGGAACACTTTTTTCAGAAAACCTTCAAACTTTGC
GTAGTGTAGGATATATTTTAAAGCATGTCGAAACCGATTAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-112)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (146-220)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus pneumoniae TIGR4	88.393	99.115	0.876
ciaR	Streptococcus pneumoniae D39	88.393	99.115	0.876
ciaR	Streptococcus pneumoniae R6	88.393	99.115	0.876
ciaR	Streptococcus pneumoniae Rx1	88.393	99.115	0.876
ciaR	Streptococcus mutans UA159	88.688	97.788	0.867
vicR	Streptococcus mutans UA159	35.193	100	0.363
covR	Lactococcus lactis subsp. lactis strain DGCC12653	36.607	99.115	0.363