Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   R8586_RS06335 Genome accession   NZ_AP026922
Coordinates   1227294..1227863 (-) Length   189 a.a.
NCBI ID   WP_164993539.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700038     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1222294..1232863
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8586_RS06305 (PC0038_12520) - 1222639..1223574 (+) 936 WP_000401798.1 bifunctional oligoribonuclease/PAP phosphatase NrnA -
  R8586_RS06310 (PC0038_12530) - 1223670..1223912 (+) 243 WP_000710764.1 type B 50S ribosomal protein L31 -
  R8586_RS06315 (PC0038_12540) - 1223969..1224187 (-) 219 WP_001818873.1 hypothetical protein -
  R8586_RS06320 - 1224184..1224918 (-) 735 Protein_1251 transposase -
  R8586_RS06325 (PC0038_12570) gdhA 1225259..1226605 (+) 1347 WP_000199560.1 NADP-specific glutamate dehydrogenase -
  R8586_RS06330 (PC0038_12580) - 1227111..1227281 (-) 171 WP_000711939.1 hypothetical protein -
  R8586_RS06335 (PC0038_12590) comA 1227294..1227863 (-) 570 WP_164993539.1 ATP-binding cassette domain-containing protein Regulator
  R8586_RS06340 - 1227889..1228694 (-) 806 Protein_1255 IS5 family transposase -
  R8586_RS06345 - 1228957..1229522 (+) 566 Protein_1256 IS630 family transposase -
  R8586_RS06350 (PC0038_12630) - 1229634..1230083 (-) 450 WP_000424223.1 YhcH/YjgK/YiaL family protein -
  R8586_RS06355 cdd 1230096..1230501 (-) 406 Protein_1258 cytidine deaminase -
  R8586_RS06365 (PC0038_12660) - 1230588..1231043 (-) 456 WP_001000318.1 HIT family protein -
  R8586_RS06370 (PC0038_12670) - 1231065..1232525 (-) 1461 WP_000272434.1 FAD-dependent oxidoreductase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 21140.56 Da        Isoelectric Point: 8.4246

>NTDB_id=82320 R8586_RS06335 WP_164993539.1 1227294..1227863(-) (comA) [Streptococcus pneumoniae strain PZ900700038]
MPSGLYKIDTGKVLFYGININQIDKKILSQNLGVVPQDSFLLNRSILDNITLKHEVTSQKIEEVCKAVQIYDEIMAMPMK
FNTIISEMGSNISGGQRQQIALARALINNPSIVILDEATSALDTINEERITKYIQSQGCTQIIIAHRLSTIKDADIIFVM
KGGKIVESGNHKYLITLGGEYYSLYTKRK

Nucleotide


Download         Length: 570 bp        

>NTDB_id=82320 R8586_RS06335 WP_164993539.1 1227294..1227863(-) (comA) [Streptococcus pneumoniae strain PZ900700038]
ATACCATCAGGATTATATAAGATTGATACAGGAAAAGTTTTATTTTATGGTATAAATATTAATCAAATAGATAAAAAAAT
ATTAAGTCAAAATTTAGGAGTAGTTCCACAGGATTCATTTTTATTGAACCGAAGTATTCTTGATAATATAACTTTAAAGC
ACGAAGTTACTTCACAAAAGATAGAGGAAGTTTGTAAAGCAGTTCAAATCTATGATGAAATCATGGCTATGCCGATGAAA
TTTAATACTATCATCTCAGAGATGGGGTCAAATATTTCAGGTGGGCAAAGGCAACAGATAGCACTGGCACGTGCATTAAT
AAATAATCCTAGTATTGTAATTTTAGATGAAGCAACTAGTGCATTAGACACTATTAATGAGGAAAGAATAACAAAGTATA
TACAAAGTCAGGGTTGTACTCAAATAATTATAGCTCATAGATTGTCAACGATTAAGGATGCGGATATTATTTTTGTAATG
AAAGGTGGTAAGATTGTTGAGTCAGGAAATCATAAGTACTTAATAACTCTTGGTGGAGAGTACTACAGCTTATATACAAA
AAGGAAATGA

Domains

Predicted by InterProScan.

ABC transporter (ABC_tran)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus gordonii str. Challis substr. CH1

41.848

97.354

0.407
  comA Streptococcus mitis NCTC 12261

41.398

98.413

0.407
  comA Streptococcus mitis SK321

40.86

98.413

0.402
  comA/nlmT Streptococcus mutans UA159

41.304

97.354

0.402
  comA Streptococcus pneumoniae R6

40.323

98.413

0.397
  comA Streptococcus pneumoniae D39

40.323

98.413

0.397
  comA Streptococcus pneumoniae Rx1

40.323

98.413

0.397
  comA Streptococcus pneumoniae TIGR4

39.247

98.413

0.386

Multiple sequence alignment