Detailed information NTG0821650

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: QFC88_RS01775
• Genome accession: NZ_CP123615
• Coordinates: 266916..268205 (-)
• Length: 429 a.a.
• NCBI ID: WP_002374326.1
• Uniprot ID: A0A4Y3JMI1
• Organism: Enterococcus lactis strain J-1-A
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 261916..273205

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QFC88_RS01745 (QFC88_01740)	-	262118..263071 (-)	954	WP_002374319.1	glycosyltransferase family 2 protein	-
QFC88_RS01750 (QFC88_01745)	-	263254..263604 (-)	351	WP_002292629.1	PepSY domain-containing protein	-
QFC88_RS01755 (QFC88_01750)	pepA	263804..264883 (+)	1080	WP_002374321.1	glutamyl aminopeptidase	-
QFC88_RS01760 (QFC88_01755)	-	265026..265346 (+)	321	WP_002374322.1	thioredoxin family protein	-
QFC88_RS01765 (QFC88_01760)	-	265368..265832 (+)	465	WP_002292633.1	universal stress protein	-
QFC88_RS01770 (QFC88_01765)	ytpR	266149..266754 (+)	606	WP_002374324.1	YtpR family tRNA-binding protein	-
QFC88_RS01775 (QFC88_01770)	htrA	266916..268205 (-)	1290	WP_002374326.1	trypsin-like peptidase domain-containing protein	Regulator
QFC88_RS01780 (QFC88_01775)	rlmH	268633..269112 (+)	480	WP_025478483.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
QFC88_RS01785 (QFC88_01780)	-	269162..270010 (+)	849	WP_002375160.1	hypothetical protein	-
QFC88_RS01790 (QFC88_01785)	-	270348..271286 (+)	939	Protein_265	alpha-L-rhamnosidase	-
QFC88_RS01795 (QFC88_01790)	-	271266..271568 (+)	303	WP_237725998.1	alpha-L-rhamnosidase C-terminal domain-containing protein	-
QFC88_RS01800 (QFC88_01795)	-	271746..272306 (-)	561	WP_002326412.1	TetR/AcrR family transcriptional regulator	-
QFC88_RS01805 (QFC88_01800)	-	272448..273062 (+)	615	WP_025478569.1	GNAT family N-acetyltransferase	-

Sequence

Protein

• Length: 429 a.a.
• Molecular weight: 44939.95 Da
• Isoelectric Point: 4.5419

>NTDB_id=821650 QFC88_RS01775 WP_002374326.1 266916..268205(-) (htrA) [Enterococcus lactis strain J-1-A]
MDRKNVTPKMKKNKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAMGTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKA
VDKVQDAVVSVINLQSQNQSSGFGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYIVTNNHVVDGQQGLEVLMKD
GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYANSVTSGIISSLNRQVTSTNESNE
TVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSKIASTSESTSNVNVEGMGFAIPSNDVVNIINQLEKDGKVTRPALG
ITMVDLSAVSTQQQEQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKKVGDSVKIT
YYEGSKEKTTTVELTIDQSALKQNQNSEN

Nucleotide

• Length: 1290 bp

>NTDB_id=821650 QFC88_RS01775 WP_002374326.1 266916..268205(-) (htrA) [Enterococcus lactis strain J-1-A]
ATGGATAGAAAAAATGTGACACCAAAGATGAAAAAAAATAAAAATAATAGCCTCTGGCGTAAGTTAGGTCTGGGGCTTGT
TGGAGGGATCGTTGGAGGACTACTGACAGCTGGCATTTTTTATGCAGCGATGGGCACTGGCAACAATAGTTCTACTGCTA
CAAGCGGCAATCAGAATTCTGCCGGTGAAACAGTTGTGGAAAATGTCAAAGTCAATGTAGATTCTGATATCACCAAAGCG
GTAGATAAAGTTCAAGACGCTGTCGTTTCTGTTATCAACTTACAAAGTCAAAACCAATCAAGCGGTTTTGGCGGACTATT
CGGGCAGCAAGAAGAAAGTAGCAGCTCAGATGATAGTAATTTGGAAGCTTATAGTGAAGGAAGCGGCGTGATCTACAAAA
AAGACGGAAATACTGCTTATATAGTCACAAACAACCACGTAGTAGATGGACAGCAAGGTCTTGAAGTCTTGATGAAAGAC
GGTACGAAGGTAAAAGCTGAATTAGTTGGAACAGATGCTTATTCAGATTTAGCGGTGTTGAAGATCAATTCAGATAAAGT
CGAAACAGTTGCCTCTTTTGGTGACTCAAGTGCTCTGAAGGTTGGTGAACCTGCGATTGCGATTGGTTCCCCATTAGGAT
CTGAATATGCGAATTCTGTCACTTCAGGAATCATTTCTTCCTTGAACCGACAAGTAACAAGTACGAATGAATCGAACGAA
ACAGTCAATATCAATGCGATCCAAACAGATGCAGCGATCAACCCGGGAAATTCTGGTGGTCCTTTAGTGAATATCGAAGG
ACAAGTTATCGGTATCAACTCAAGTAAGATCGCAAGTACTTCTGAATCTACTTCTAACGTAAATGTAGAAGGAATGGGAT
TTGCCATCCCAAGTAACGATGTAGTGAATATCATCAATCAACTGGAAAAAGACGGAAAAGTGACACGTCCAGCTCTAGGT
ATCACAATGGTCGACTTATCTGCCGTTTCTACTCAGCAACAAGAACAAATCTTGAAGATTCCTTCATCTGTAACTAACGG
TGTCATCGTGACAAATGTCCAAACAGCTACACCGGCTGAAAAAGCTGGATTGAAACAATATGATGTCATTACTAAGATCG
ATGACAAAGAAGTTTCTTCTGGCGTAGAACTTCAATCTGCTTTGTATAAGAAAAAAGTGGGAGATTCTGTCAAAATCACT
TACTATGAAGGCTCGAAAGAAAAAACAACTACTGTTGAATTGACGATCGATCAATCGGCATTAAAACAAAATCAAAATAG
TGAAAATTAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (127-272)

• Peptidase family M50 (Peptidase_M50) (10-417)

• PDZ domain (PDZ_2) (317-414)

3D structure

• AlphaFold DB: A0A4Y3JMI1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus gordonii str. Challis substr. CH1	54.315	91.841	0.499
htrA	Streptococcus mutans UA159	59.887	82.517	0.494
htrA	Streptococcus mitis NCTC 12261	52.778	92.308	0.487
htrA	Streptococcus pneumoniae TIGR4	59.05	78.555	0.464
htrA	Streptococcus pneumoniae D39	59.05	78.555	0.464
htrA	Streptococcus pneumoniae Rx1	59.05	78.555	0.464
htrA	Streptococcus pneumoniae R6	59.05	78.555	0.464