Detailed information NTG0082084

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: R8566_RS06540
• Genome accession: NZ_AP026920
• Coordinates: 1294606..1295175 (-)
• Length: 189 a.a.
• NCBI ID: WP_075219010.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900700014
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1289606..1300175

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8566_RS06510 (PC0014_12950)	-	1289711..1289953 (+)	243	WP_000710764.1	type B 50S ribosomal protein L31	-
R8566_RS06515 (PC0014_12960)	-	1290010..1290588 (-)	579	WP_000252103.1	hypothetical protein	-
R8566_RS06520 (PC0014_12970)	efeB	1290563..1291576 (-)	1014	Protein_1289	iron uptake transporter deferrochelatase/peroxidase subunit	-
R8566_RS06525	-	1291546..1292037 (-)	492	Protein_1290	winged helix-turn-helix domain-containing protein	-
R8566_RS06530 (PC0014_12990)	gdhA	1292571..1293917 (+)	1347	WP_000199559.1	NADP-specific glutamate dehydrogenase	-
R8566_RS06535 (PC0014_13000)	-	1294423..1294593 (-)	171	WP_000711943.1	hypothetical protein	-
R8566_RS06540 (PC0014_13010)	comA	1294606..1295175 (-)	570	WP_075219010.1	ATP-binding cassette domain-containing protein	Regulator
R8566_RS06545	-	1295201..1296006 (-)	806	Protein_1294	IS5 family transposase	-
R8566_RS06550	-	1296099..1296761 (-)	663	Protein_1295	IS66 family transposase	-
R8566_RS06555 (PC0014_13060)	-	1296867..1297310 (-)	444	Protein_1296	IS66 family transposase	-
R8566_RS06560	-	1297283..1297591 (+)	309	Protein_1297	transposase	-
R8566_RS06565 (PC0014_13080)	tnpB	1297746..1298012 (-)	267	WP_001248801.1	IS66 family insertion sequence element accessory protein TnpB	-
R8566_RS06570	-	1298050..1298235 (-)	186	WP_001136124.1	hypothetical protein	-
R8566_RS06575 (PC0014_13100)	-	1298508..1299119 (-)	612	WP_000251935.1	V-type ATP synthase subunit D	-

Sequence

Protein

• Length: 189 a.a.
• Molecular weight: 21129.56 Da
• Isoelectric Point: 8.4271

>NTDB_id=82084 R8566_RS06540 WP_075219010.1 1294606..1295175(-) (comA) [Streptococcus pneumoniae strain PZ900700014]
MPSGLYKIDTGKVLFDGININQIDKKILSQNLGVVPQDSFLLNRSILDNITLKNEVTSQKIEEVCKAVQIYDEIMAMPMK
FNTIISEMGSNISGGQRQRIALARALINNPSIVILDEATSALDTINEERITKYIKSQGCTQIIVAHRLSTIKDADIIFVM
KGGKIVESGNHKYLMELGGEYYSLYTKRK

Nucleotide

• Length: 570 bp

>NTDB_id=82084 R8566_RS06540 WP_075219010.1 1294606..1295175(-) (comA) [Streptococcus pneumoniae strain PZ900700014]
ATACCATCAGGATTATATAAGATTGATACAGGAAAAGTTTTATTTGATGGTATAAATATTAATCAAATAGATAAAAAAAT
ATTAAGTCAAAATTTAGGAGTAGTTCCACAGGATTCATTTTTATTGAACCGAAGTATTCTTGATAATATAACTTTAAAGA
ACGAAGTTACTTCACAAAAGATAGAGGAAGTTTGTAAAGCAGTTCAAATCTATGATGAAATCATGGCTATGCCGATGAAA
TTTAATACTATCATCTCAGAGATGGGTTCAAATATTTCAGGTGGTCAAAGACAACGGATAGCACTGGCACGTGCATTAAT
AAATAATCCTAGTATTGTAATTTTAGATGAAGCAACTAGTGCTTTAGACACTATTAATGAGGAAAGAATAACAAAGTATA
TAAAAAGTCAGGGCTGTACTCAAATAATTGTAGCTCATAGATTGTCAACGATTAAGGATGCGGATATTATTTTTGTAATG
AAAGGTGGTAAGATTGTTGAGTCAGGAAATCATAAGTACTTAATGGAGCTTGGTGGAGAGTACTACAGCTTATATACAAA
AAGGAAATGA

Domains

Predicted by InterProScan.

• ABC transporter (ABC_tran) (3-120)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus gordonii str. Challis substr. CH1	41.489	99.471	0.413
comA/nlmT	Streptococcus mutans UA159	41.848	97.354	0.407
comA	Streptococcus mitis NCTC 12261	41.398	98.413	0.407
comA	Streptococcus mitis SK321	40.86	98.413	0.402
comA	Streptococcus pneumoniae Rx1	40.323	98.413	0.397
comA	Streptococcus pneumoniae D39	40.323	98.413	0.397
comA	Streptococcus pneumoniae R6	40.323	98.413	0.397
comA	Streptococcus pneumoniae TIGR4	39.247	98.413	0.386