Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   QAO39_RS03195 Genome accession   NZ_CP123158
Coordinates   632017..632733 (-) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain BE-MSSA9     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 627017..637733
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QAO39_RS03175 (QAO39_03170) - 628109..629059 (+) 951 WP_072496928.1 LacI family DNA-binding transcriptional regulator -
  QAO39_RS03180 (QAO39_03175) - 629208..630692 (+) 1485 WP_000141416.1 sucrose-6-phosphate hydrolase -
  QAO39_RS03185 (QAO39_03180) - 630689..631648 (+) 960 WP_001253314.1 carbohydrate kinase family protein -
  QAO39_RS03190 (QAO39_03185) - 631836..631945 (-) 110 Protein_623 hypothetical protein -
  QAO39_RS03195 (QAO39_03190) agrA 632017..632733 (-) 717 WP_000688498.1 quorum-sensing response regulator AgrA Regulator
  QAO39_RS03200 (QAO39_03195) agrC 632752..634035 (-) 1284 WP_000447888.1 quorum-sensing sensor histidine kinase AgrC -
  QAO39_RS03205 (QAO39_03200) agrD 634065..634208 (-) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  QAO39_RS03210 (QAO39_03205) - 634211..634774 (-) 564 WP_001105696.1 accessory gene regulator AgrB -
  QAO39_RS03215 (QAO39_03210) hld 635064..635144 (+) 81 WP_000046022.1 delta-hemolysin -
  QAO39_RS03220 (QAO39_03215) - 635744..636529 (-) 786 WP_165469131.1 carbon-nitrogen family hydrolase -
  QAO39_RS03225 (QAO39_03220) - 636890..637516 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=819685 QAO39_RS03195 WP_000688498.1 632017..632733(-) (agrA) [Staphylococcus aureus strain BE-MSSA9]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=819685 QAO39_RS03195 WP_000688498.1 632017..632733(-) (agrA) [Staphylococcus aureus strain BE-MSSA9]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996