Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   QAY79_RS02660 Genome accession   NZ_CP123154
Coordinates   553560..554909 (+) Length   449 a.a.
NCBI ID   WP_061823522.1    Uniprot ID   -
Organism   Staphylococcus aureus strain GE-MRSA17     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 548118..563324 553560..554909 within 0


Gene organization within MGE regions


Location: 548118..563324
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QAY79_RS02640 (QAY79_02650) - 548118..549608 (-) 1491 WP_000554504.1 RNA-binding domain-containing protein -
  QAY79_RS02645 (QAY79_02655) - 550061..551110 (-) 1050 WP_000613248.1 hypothetical protein -
  QAY79_RS02650 (QAY79_02660) ssb 551249..551539 (+) 291 WP_001036438.1 cassette chromosome ssDNA-binding protein -
  QAY79_RS02655 (QAY79_02665) cch1 551539..553326 (+) 1788 WP_000122620.1 cassette chromosome replicative helicase -
  QAY79_RS02660 (QAY79_02670) ccrA 553560..554909 (+) 1350 WP_061823522.1 cassette chromosome recombinase CcrA Machinery gene
  QAY79_RS02665 (QAY79_02675) ccrB 554931..556559 (+) 1629 WP_001186608.1 cassette chromosome recombinase CcrB Machinery gene
  QAY79_RS02670 (QAY79_02680) - 557081..557431 (+) 351 WP_000849672.1 SAUGI family uracil-DNA glycosylase inhibitor -
  QAY79_RS02675 (QAY79_02685) - 557518..557829 (+) 312 WP_000700851.1 DUF960 family protein -
  QAY79_RS02680 (QAY79_02690) - 557844..558350 (+) 507 WP_001092189.1 DUF1643 domain-containing protein -
  QAY79_RS02685 (QAY79_02695) - 558399..560009 (+) 1611 Protein_515 IS1182 family transposase -
  QAY79_RS02690 (QAY79_02700) - 560000..560242 (-) 243 Protein_516 type I restriction enzyme endonuclease domain-containing protein -
  QAY79_RS02695 (QAY79_02705) - 560232..561218 (-) 987 WP_001549960.1 beta-lactam sensor/signal transducer MecR1 -
  QAY79_RS02700 (QAY79_02710) mecA 561315..563324 (+) 2010 WP_063852655.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 52672.35 Da        Isoelectric Point: 9.9639

>NTDB_id=819601 QAY79_RS02660 WP_061823522.1 553560..554909(+) (ccrA) [Staphylococcus aureus strain GE-MRSA17]
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQITQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYHVHILSVHDGYFDMDQAFDRLKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYDYH
HGTFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRLQKQTKQTPSDNQLKQKIKCPCCNATLTNMTIRKKNHTLRYYVCPKNMNASRFVCDFKGINAQTLEDKVLEV
CRDFYQNQRIYTKIKSAIDKRIKRQRNIEKHHTLTQEQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSINGHQIQHIIQ
NIIQKRFTLNILYPYIETIHITKDKNLIGIYFKNEPLNIVNQTMQSSIA

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=819601 QAY79_RS02660 WP_061823522.1 553560..554909(+) (ccrA) [Staphylococcus aureus strain GE-MRSA17]
ATGAAACAAGTCATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAAGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGTCGCAAAGATAATCGTAGTGGGT
ATCGACAAATAACACAATTAATTCAACAAGGACAGTGTGACATATTATGCTGTTATCGTCTTAATAGGTTGCATCGTAAT
CTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACGTACCATGTTCATATCTTAAGCGTACATGATGGTTACTTTGA
TATGGATCAAGCTTTCGACCGACTCAAGCTTAATATCTTCATCAGTTTAGCCGAACTTGAATCGGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACACATGCACCTTTTGGTTACGATTATCAC
CACGGAACATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGTCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATCATCA
ATCCTAATTATTGTGGTCGTGTCAACAATCAATATGGCCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATTGCAAAAACAAACCAAACAGACACCTTCGGATAATCAACTCAAACAAAAAATCAA
ATGCCCATGTTGTAATGCAACACTTACAAATATGACCATTAGAAAAAAGAATCATACATTACGTTACTACGTCTGTCCTA
AAAACATGAATGCTTCACGCTTTGTCTGTGATTTTAAAGGCATCAATGCACAAACACTTGAAGATAAAGTATTAGAAGTG
TGCCGAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAAGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACACATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATTGATGCAGAAACGTTCA
GAGAGCAAACACAATCATTACGTCAACAACCGCAACGCACTACATCTATCAATGGGCATCAAATACAACACATCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCCTATATTGAAACCATTCACATTACGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATTGTCAATCAAACCATGCAATCATCGATTGCATAA

Domains

Predicted by InterproScan.

Resolvase, N terminal domain (Resolvase)

(4-147)

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-321)

Recombinase (Recombinase)

(169-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus N315

97.105

100

0.971
  ccrA Staphylococcus aureus COL

75.724

100

0.757