Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   R4714_RS00870 Genome accession   NZ_CP137099
Coordinates   170604..171143 (-) Length   179 a.a.
NCBI ID   WP_225353592.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 20824-4     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 165604..176143
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4714_RS00840 - 165871..166806 (+) 936 WP_061647412.1 bifunctional oligoribonuclease/PAP phosphatase NrnA -
  R4714_RS00845 - 166902..167144 (+) 243 WP_000710764.1 type B 50S ribosomal protein L31 -
  R4714_RS00850 - 167201..167419 (-) 219 WP_000028151.1 hypothetical protein -
  R4714_RS00855 - 167416..167998 (-) 583 Protein_168 transposase -
  R4714_RS00860 gdhA 168526..169872 (+) 1347 WP_219576806.1 NADP-specific glutamate dehydrogenase -
  R4714_RS00865 - 170378..170548 (-) 171 WP_000711943.1 hypothetical protein -
  R4714_RS00870 comA 170604..171143 (-) 540 WP_225353592.1 ATP-binding cassette domain-containing protein Regulator
  R4714_RS00875 - 171169..171933 (-) 765 Protein_172 transposase family protein -
  R4714_RS00880 - 172352..173047 (+) 696 Protein_173 IS630 family transposase -
  R4714_RS00885 - 173281..173733 (-) 453 Protein_174 hypothetical protein -
  R4714_RS00890 - 173735..174022 (-) 288 WP_000869754.1 hypothetical protein -
  R4714_RS00895 - 174379..175698 (-) 1320 Protein_176 hypothetical protein -

Sequence

Protein


Download         Length: 179 a.a.        Molecular weight: 19891.09 Da        Isoelectric Point: 7.2433

>NTDB_id=818276 R4714_RS00870 WP_225353592.1 170604..171143(-) (comA) [Streptococcus pneumoniae strain 20824-4]
MLSRLYKIDTGKVLFDGVNINQIDKKILSQNLGVVPQDSFLLNRSILDNITLKHEVTSQKIEEVCKAVQIYDEITAMPMK
FNTIISEMGSNISGGQRQRIALARALINNPSIVILDEATSALDTINEERITKYIQSQGCTQIIIAHRLSTIKDADIIFVM
KGGKIVESGNHKYLMDLGG

Nucleotide


Download         Length: 540 bp        

>NTDB_id=818276 R4714_RS00870 WP_225353592.1 170604..171143(-) (comA) [Streptococcus pneumoniae strain 20824-4]
ATACTATCAAGATTATATAAGATTGATACAGGAAAAGTTTTATTTGATGGTGTAAATATTAATCAAATAGATAAAAAAAT
ATTAAGTCAAAATTTAGGAGTAGTTCCACAGGATTCGTTTTTATTGAACAGAAGTATTCTTGATAACATAACTTTAAAGC
ACGAAGTTACTTCACAAAAGATAGAGGAAGTTTGTAAAGCAGTTCAAATCTATGATGAAATCACGGCTATGCCGATGAAA
TTTAATACTATCATCTCAGAGATGGGGTCAAATATTTCAGGTGGGCAAAGGCAACGGATAGCACTGGCACGTGCATTAAT
AAATAATCCTAGTATTGTAATTTTAGATGAAGCAACTAGTGCATTAGACACTATTAATGAGGAAAGAATAACAAAGTATA
TACAAAGTCAGGGTTGTACTCAAATAATTATAGCTCATAGATTGTCAACGATTAAGGATGCGGATATTATTTTTGTAATG
AAAGGTGGTAAGATTGTTGAGTCAGGAAATCATAAGTACTTAATGGATCTTGGTGGATAG

Domains

Predicted by InterProScan.

ABC transporter (ABC_tran)

(1-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus gordonii str. Challis substr. CH1

42.077

100

0.43
  comA Streptococcus mitis NCTC 12261

42.541

100

0.43
  comA Streptococcus mitis SK321

41.989

100

0.425
  comA Streptococcus pneumoniae R6

41.436

100

0.419
  comA Streptococcus pneumoniae Rx1

41.436

100

0.419
  comA Streptococcus pneumoniae D39

41.436

100

0.419
  comA/nlmT Streptococcus mutans UA159

41.011

99.441

0.408
  comA Streptococcus pneumoniae TIGR4

40.331

100

0.408
  rcrQ Streptococcus mutans UA159

37.158

100

0.38