Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGD   Type   Machinery gene
Locus tag   R3H37_RS00670 Genome accession   NZ_CP136948
Coordinates   105320..105748 (+) Length   142 a.a.
NCBI ID   WP_129284411.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain Spyo01     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 100320..110748
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R3H37_RS00650 (R3H37_00650) - 102651..103016 (+) 366 WP_002986560.1 DUF1033 family protein -
  R3H37_RS00655 (R3H37_00655) comGA 103109..104047 (+) 939 WP_023079010.1 competence type IV pilus ATPase ComGA Machinery gene
  R3H37_RS00660 (R3H37_00660) comGB 103983..105017 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  R3H37_RS00665 (R3H37_00665) comGC 105019..105345 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  R3H37_RS00670 (R3H37_00670) comGD 105320..105748 (+) 429 WP_129284411.1 competence type IV pilus minor pilin ComGD Machinery gene
  R3H37_RS00675 (R3H37_00675) comGE 105705..105989 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE Machinery gene
  R3H37_RS00680 (R3H37_00680) comGF 105982..106416 (+) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  R3H37_RS00685 (R3H37_00685) comGG 106400..106726 (+) 327 WP_009880358.1 competence type IV pilus minor pilin ComGG -
  R3H37_RS00690 (R3H37_00690) comGH 106824..107777 (+) 954 WP_002987790.1 class I SAM-dependent methyltransferase Machinery gene
  R3H37_RS00695 (R3H37_00695) - 107836..109032 (+) 1197 WP_002987791.1 acetate kinase -
  R3H37_RS00700 (R3H37_00700) - 109218..109526 (+) 309 WP_030126458.1 hypothetical protein -
  R3H37_RS00705 (R3H37_00705) proC 109609..110379 (-) 771 WP_063631714.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 142 a.a.        Molecular weight: 16310.08 Da        Isoelectric Point: 10.4284

>NTDB_id=816404 R3H37_RS00670 WP_129284411.1 105320..105748(+) (comGD) [Streptococcus pyogenes strain Spyo01]
MKKPVLAIKAFTLLETLLSLSVMSFIILGLSVPVTKSYQKVEEHLFFSHFEHLYRHQQKLAILQQKKRVLDISSTKIVTE
GNSLTVPKSITVNHPYRLVIDQMGGNHSLAKIIFDMTDRRFKYQFYLGSGNYQKTSQSLHSP

Nucleotide


Download         Length: 429 bp        

>NTDB_id=816404 R3H37_RS00670 WP_129284411.1 105320..105748(+) (comGD) [Streptococcus pyogenes strain Spyo01]
ATGAAAAAGCCCGTCTTAGCAATTAAAGCTTTTACTTTGCTTGAAACTTTACTAAGTTTGTCAGTGATGAGTTTCATTAT
ATTGGGATTGTCTGTACCAGTGACAAAAAGCTATCAAAAAGTAGAAGAGCATCTGTTTTTTAGCCATTTTGAACATTTGT
ATCGACATCAGCAAAAGTTAGCCATATTACAGCAAAAAAAGCGCGTCTTGGATATTTCTTCAACAAAAATTGTTACAGAA
GGTAATAGCCTAACAGTTCCTAAATCAATAACAGTGAATCATCCTTATCGGTTAGTTATTGATCAGATGGGAGGCAACCA
TTCCTTAGCTAAAATTATTTTTGACATGACTGATCGACGCTTTAAATACCAATTTTATCTAGGGAGTGGGAATTATCAAA
AAACAAGTCAAAGCTTACATAGCCCTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGD Streptococcus mutans UA159

45.736

90.845

0.415
  comGD Streptococcus mutans UA140

45.736

90.845

0.415
  comGD/cglD Streptococcus mitis NCTC 12261

41.176

95.775

0.394
  comGD Streptococcus gordonii str. Challis substr. CH1

41.221

92.254

0.38
  comGD/cglD Streptococcus pneumoniae R6

41.732

89.437

0.373
  comGD/cglD Streptococcus mitis SK321

41.732

89.437

0.373
  comGD/cglD Streptococcus pneumoniae Rx1

41.732

89.437

0.373
  comGD/cglD Streptococcus pneumoniae D39

41.732

89.437

0.373