Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   R8775_RS06410 Genome accession   NZ_AP026915
Coordinates   1244286..1245023 (-) Length   245 a.a.
NCBI ID   WP_050233469.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700005     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1239286..1250023
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8775_RS06390 (PC0005_12570) msrB 1240295..1241233 (-) 939 WP_000818207.1 peptide-methionine (R)-S-oxide reductase MsrB -
  R8775_RS06395 (PC0005_12580) - 1241300..1241902 (-) 603 WP_317680891.1 hypothetical protein -
  R8775_RS06400 (PC0005_12590) thrB 1241978..1242847 (-) 870 WP_000692438.1 homoserine kinase -
  R8775_RS06405 (PC0005_12600) - 1242849..1244135 (-) 1287 WP_000216382.1 homoserine dehydrogenase -
  R8775_RS06410 (PC0005_12610) mecA 1244286..1245023 (-) 738 WP_050233469.1 adaptor protein MecA Regulator
  R8775_RS06415 (PC0005_12620) - 1245223..1246257 (-) 1035 WP_000461502.1 hypothetical protein -
  R8775_RS06420 (PC0005_12630) - 1246286..1247719 (-) 1434 WP_317680892.1 O-antigen polysaccharide polymerase Wzy family protein -
  R8775_RS06425 (PC0005_12640) - 1247735..1248721 (-) 987 WP_050233468.1 glycosyltransferase family 2 protein -
  R8775_RS06430 (PC0005_12650) - 1248723..1249826 (-) 1104 WP_000225892.1 glycosyltransferase -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28382.12 Da        Isoelectric Point: 3.9741

>NTDB_id=81492 R8775_RS06410 WP_050233469.1 1244286..1245023(-) (mecA) [Streptococcus pneumoniae strain PZ900700005]
MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAILDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKI
DQNLDFEDLSDLPDMEELAQMSPDEFIKTLEKSIADKTEDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDSDISRSVLQEYGQVLMSHDAVLN
LQKIG

Nucleotide


Download         Length: 738 bp        

>NTDB_id=81492 R8775_RS06410 WP_050233469.1 1244286..1245023(-) (mecA) [Streptococcus pneumoniae strain PZ900700005]
ATGAAAATGAAACAAATTAGTGATACAACTTTAAAAATCACGATGTCTTTAGAGGATTTGATGGATCGTGGAATGGAGAT
TGCTGACTTTCTCGTTCCTCAAGAAAAAACAGAAGAGTTCTTTTATGCTATCTTGGATGAGCTAGAGATGCCTGATAGCT
TTCTGGATACAGGCATGTTGAGCTTCCGTGTGACTCCAAAACCTGATAAGGTAGATGTCTTTGTGACCAAGTCAAAGATT
GACCAAAATCTAGATTTTGAAGACTTATCGGATTTGCCAGATATGGAAGAATTAGCTCAAATGTCTCCAGATGAATTTAT
CAAAACCCTGGAAAAAAGCATCGCAGACAAAACCGAGGATGATATCGAAGCCATTCAATCTCTTGAGCAAGTTGAAGCCA
AGGAAGAAGAGCAAGAGCAGGCTGAACAAGAAGCTGAGAGTAAGAAAGAACCTTACATCTACTACATCCTTTCTTTTGCT
AAGTTGGCTGACTTGGTAGCTTTTGCCAAGACAGTGACTTTTGAAATGGAAACTTCTGAACTCTACAAAATGAACGAGCG
CTATTATTTGACCATTTTAGTGGATATTGAAAATCATCCAAGCCCATATCCAGCTTGGCTGTTGGCCCGTATGCGCGAGT
TTGCAGACGATAGTGATATCAGTCGCTCAGTCTTACAAGAGTATGGTCAAGTCTTGATGAGTCACGATGCAGTGCTCAAT
CTGCAAAAAATCGGCTAA

Domains

Predicted by InterProScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

99.184

100

0.992
  mecA Streptococcus pneumoniae D39

99.184

100

0.992
  mecA Streptococcus pneumoniae R6

99.184

100

0.992
  mecA Streptococcus pneumoniae TIGR4

98.776

100

0.988
  mecA Streptococcus thermophilus LMD-9

47.791

100

0.486
  mecA Streptococcus thermophilus LMG 18311

47.39

100

0.482
  mecA Streptococcus mutans UA159

48.163

100

0.482

Multiple sequence alignment