Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   R8775_RS06215 Genome accession   NZ_AP026915
Coordinates   1212002..1212643 (-) Length   213 a.a.
NCBI ID   WP_000151458.1    Uniprot ID   Q8DPF9
Organism   Streptococcus pneumoniae strain PZ900700005     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1207002..1217643
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8775_RS06185 (PC0005_12190) - 1207321..1208256 (+) 936 WP_000401770.1 bifunctional oligoribonuclease/PAP phosphatase NrnA -
  R8775_RS06190 (PC0005_12200) - 1208352..1208594 (+) 243 WP_317680888.1 type B 50S ribosomal protein L31 -
  R8775_RS06195 (PC0005_12210) - 1208651..1208869 (-) 219 WP_000028153.1 hypothetical protein -
  R8775_RS06200 - 1208866..1209442 (-) 577 Protein_1226 transposase -
  R8775_RS06205 (PC0005_12220) gdhA 1209977..1211323 (+) 1347 WP_000199534.1 NADP-specific glutamate dehydrogenase -
  R8775_RS06210 (PC0005_12230) - 1211819..1211989 (-) 171 WP_000711943.1 hypothetical protein -
  R8775_RS06215 (PC0005_12240) comA 1212002..1212643 (-) 642 WP_000151458.1 ATP-binding cassette domain-containing protein Regulator
  R8775_RS06220 - 1212768..1212954 (-) 187 Protein_1230 hypothetical protein -
  R8775_RS06225 (PC0005_12250) - 1212915..1213352 (+) 438 WP_001856204.1 hypothetical protein -
  R8775_RS06230 - 1213354..1213422 (+) 69 WP_225208679.1 hypothetical protein -
  R8775_RS06235 (PC0005_12260) - 1213643..1213837 (-) 195 Protein_1233 ROK family protein -
  R8775_RS06240 (PC0005_12270) - 1213864..1214781 (-) 918 Protein_1234 dihydrodipicolinate synthase family protein -
  R8775_RS06245 (PC0005_12280) - 1214813..1215220 (-) 408 WP_000216067.1 cytidine deaminase -
  R8775_RS06250 (PC0005_12290) - 1215508..1215996 (-) 489 WP_000872894.1 phosphatidylglycerophosphatase A -
  R8775_RS06255 (PC0005_12300) - 1216001..1217410 (-) 1410 WP_000773464.1 hypothetical protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23486.26 Da        Isoelectric Point: 9.2387

>NTDB_id=81490 R8775_RS06215 WP_000151458.1 1212002..1212643(-) (comA) [Streptococcus pneumoniae strain PZ900700005]
MTIEPGQRIALVGQSGSGKSTLSKIPSGLYKIDTGKVLFDGVNINQIDKKILSQNLGVVPQDSFLLNRSILDNITLKHEV
TSQKIEEVCKAVQIYDEIMAMPMKFNTIISEMGSNISGGQRQRIALARALINNPSIVILDEATSALDTINEERITKYIKS
QGCTQIIVAHRLSTIKDADIIVVMKGGKIVESGNHKYLMDLGGEYYSLYTKRK

Nucleotide


Download         Length: 642 bp        

>NTDB_id=81490 R8775_RS06215 WP_000151458.1 1212002..1212643(-) (comA) [Streptococcus pneumoniae strain PZ900700005]
TTGACTATTGAGCCAGGACAGAGAATTGCACTAGTCGGTCAATCGGGGTCAGGAAAAAGTACGTTATCAAAAATACCATC
AGGATTATATAAGATTGATACAGGAAAAGTTTTATTTGATGGTGTAAATATTAATCAAATAGATAAAAAAATATTAAGTC
AAAATTTAGGAGTAGTTCCACAGGATTCGTTTTTATTGAACAGAAGTATTCTTGATAACATAACTTTAAAGCACGAAGTT
ACTTCACAAAAGATAGAGGAAGTTTGTAAAGCAGTTCAAATCTATGATGAAATCATGGCTATGCCGATGAAATTTAATAC
TATCATCTCAGAGATGGGTTCAAATATTTCAGGTGGTCAAAGACAACGGATAGCACTGGCACGTGCATTAATAAATAATC
CTAGTATTGTAATTTTAGATGAAGCAACTAGTGCTTTAGACACTATTAATGAGGAAAGAATAACAAAGTATATAAAAAGT
CAGGGCTGTACTCAAATAATTGTAGCTCATAGATTGTCAACGATTAAGGATGCGGATATTATTGTTGTAATGAAAGGTGG
TAAGATTGTTGAGTCAGGAAATCATAAGTACTTAATGGATCTTGGTGGAGAGTACTACAGCTTATATACAAAAAGGAAAT
GA

Domains

Predicted by InterProScan.

ABC transporter (ABC_tran)

(1-144)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8DPF9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

43.81

98.592

0.432
  comA Streptococcus mitis SK321

43.333

98.592

0.427
  comA Streptococcus gordonii str. Challis substr. CH1

42.453

99.531

0.423
  comA/nlmT Streptococcus mutans UA159

42.453

99.531

0.423
  comA Streptococcus pneumoniae R6

42.381

98.592

0.418
  comA Streptococcus pneumoniae Rx1

42.381

98.592

0.418
  comA Streptococcus pneumoniae D39

42.381

98.592

0.418
  comA Streptococcus pneumoniae TIGR4

41.429

98.592

0.408
  rcrQ Streptococcus mutans UA159

36.62

100

0.366

Multiple sequence alignment