NTDB

Overview

Name	dprA	Type	Machinery gene
Locus tag	QBL01_RS00145	Genome accession	NZ_CP121769
Coordinates	22214..23341 (+)	Length	375 a.a.
NCBI ID	WP_160432955.1	Uniprot ID	A0AAJ6D9T1
Organism	Glaesserella parasuis strain Z44
Function	ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Prophage	5177..21594	22214..23341	flank	620

Gene organization within MGE regions

Location: 5177..23341

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QBL01_RS00020 (QBL01_00020)	-	5177..5524 (-)	348	WP_021111456.1	helix-turn-helix transcriptional regulator	-
QBL01_RS00025 (QBL01_00025)	-	5703..6254 (+)	552	WP_042905499.1	opacity family porin	-
QBL01_RS00030 (QBL01_00030)	selA	6382..7764 (-)	1383	WP_279378498.1	L-seryl-tRNA(Sec) selenium transferase	-
QBL01_RS00040 (QBL01_00040)	-	8230..9489 (+)	1260	WP_279378721.1	integrase arm-type DNA-binding domain-containing protein	-
QBL01_RS00045 (QBL01_00045)	-	9711..10385 (+)	675	WP_279378499.1	hypothetical protein	-
QBL01_RS00050 (QBL01_00050)	-	10541..10747 (+)	207	WP_279378500.1	helix-turn-helix domain-containing protein	-
QBL01_RS00055 (QBL01_00055)	-	10764..11153 (+)	390	WP_279378501.1	hypothetical protein	-
QBL01_RS00060 (QBL01_00060)	-	11137..11439 (+)	303	WP_160405515.1	hypothetical protein	-
QBL01_RS00065 (QBL01_00065)	-	11429..11902 (+)	474	WP_160405513.1	hypothetical protein	-
QBL01_RS00070 (QBL01_00070)	-	11890..12327 (+)	438	WP_279378502.1	terminase small subunit	-
QBL01_RS00075 (QBL01_00075)	-	12382..13137 (+)	756	WP_279378503.1	antA/AntB antirepressor family protein	-
QBL01_RS00080 (QBL01_00080)	-	13186..13740 (+)	555	WP_279378504.1	ash family protein	-
QBL01_RS00085 (QBL01_00085)	-	13733..13918 (+)	186	WP_279378505.1	hypothetical protein	-
QBL01_RS00090 (QBL01_00090)	-	13911..14177 (+)	267	WP_279378506.1	hypothetical protein	-
QBL01_RS00095 (QBL01_00095)	-	14170..14478 (+)	309	WP_279378507.1	hypothetical protein	-
QBL01_RS00100 (QBL01_00100)	-	14471..14806 (+)	336	WP_279378508.1	hypothetical protein	-
QBL01_RS00105 (QBL01_00105)	-	14803..15210 (+)	408	WP_279378509.1	hypothetical protein	-
QBL01_RS00110 (QBL01_00110)	-	15194..17380 (+)	2187	WP_279378510.1	DUF927 domain-containing protein	-
QBL01_RS00115 (QBL01_00115)	-	18046..18315 (+)	270	WP_005713045.1	type II toxin-antitoxin system RelE/ParE family toxin	-
QBL01_RS00120 (QBL01_00120)	-	18343..18738 (+)	396	WP_016527749.1	helix-turn-helix transcriptional regulator	-
QBL01_RS00125 (QBL01_00125)	-	18959..19159 (+)	201	WP_005713051.1	hypothetical protein	-
QBL01_RS00130 (QBL01_00130)	-	19635..20576 (-)	942	WP_279378522.1	hypothetical protein	-
QBL01_RS00135 (QBL01_00135)	rfaD	20668..21594 (-)	927	WP_021110191.1	ADP-glyceromanno-heptose 6-epimerase	-
QBL01_RS00140 (QBL01_00140)	def	21606..22118 (-)	513	WP_010787339.1	peptide deformylase	-
QBL01_RS00145 (QBL01_00145)	dprA	22214..23341 (+)	1128	WP_160432955.1	DNA-processing protein DprA	Machinery gene

Sequence

Protein

Download Length: 375 a.a. Molecular weight: 41697.89 Da Isoelectric Point: 5.9997

                                >NTDB_id=814099 QBL01_RS00145 WP_160432955.1 22214..23341(+) (dprA) [Glaesserella parasuis strain Z44]

MTHLTKLLALLQVPQLGAQRIGRLLSEVDFGEFCQYDKIALKQMGWNERQIQRWFNPEHKWIDQALQWAEQDQQQILTLF

DEDYPFLLKQINTAPPVLFVRGNVESLSLPQIAIVGSRDYSHYGEHWAGHFSAELVKHQLAVTSGLAIGIDGFCHQRAVN

ENGITIAVLGSGLDQVYPARHKKLAEQIVATSGALVSEFFPSQPPIAENFPRRNRIISGLSLGTLVIEATVNSGSLITAR

YALEQGREVFALPNAVQNPYSEGCHKLIKEGALLVENIDDILEAIAWQRQSVHIQPSLFDTKPKQAVKSAPKLAKKLPEL

TACQQQLFEQISLEPISVDDLAKATDMAVETALIELLNLELLGVVKQVRGGYVIT

Nucleotide

Download Length: 1128 bp

                                >NTDB_id=814099 QBL01_RS00145 WP_160432955.1 22214..23341(+) (dprA) [Glaesserella parasuis strain Z44]

ATGACACATCTCACAAAATTATTAGCCCTGTTACAAGTGCCACAGCTTGGCGCACAACGTATCGGGCGGTTACTCTCGGA

AGTGGACTTTGGCGAATTTTGTCAATACGACAAAATCGCATTAAAGCAAATGGGCTGGAATGAACGGCAAATTCAGCGTT

GGTTTAATCCTGAGCATAAATGGATTGATCAGGCGTTACAATGGGCGGAACAGGATCAGCAACAGATTTTAACCTTATTT

GACGAAGATTATCCTTTTTTATTGAAGCAGATCAATACTGCTCCCCCTGTGCTTTTTGTGCGTGGGAATGTTGAAAGTTT

ATCGTTACCGCAGATAGCTATCGTCGGCAGTCGAGATTATTCCCACTATGGCGAACACTGGGCAGGGCATTTTTCGGCGG

AATTAGTGAAACATCAACTTGCTGTCACTAGTGGCTTAGCCATAGGCATAGACGGATTTTGTCATCAGCGTGCGGTCAAT

GAAAACGGGATTACTATTGCGGTTTTAGGCAGTGGTTTAGACCAAGTTTACCCTGCTCGCCATAAAAAACTTGCTGAACA

AATCGTTGCAACAAGCGGTGCGTTAGTGTCGGAATTTTTCCCTAGCCAGCCACCGATTGCTGAGAATTTTCCTAGACGAA

ATCGTATTATCAGCGGATTATCGCTCGGAACATTGGTTATTGAAGCAACAGTGAATAGTGGCTCGCTCATTACTGCCCGT

TATGCGTTAGAGCAAGGGAGAGAAGTCTTTGCATTGCCGAACGCAGTTCAAAACCCGTATAGCGAAGGGTGCCATAAATT

GATTAAAGAAGGGGCATTACTGGTTGAAAATATTGACGACATTTTAGAAGCGATTGCGTGGCAACGGCAATCAGTGCATA

TTCAACCAAGCCTGTTTGATACGAAACCTAAACAAGCGGTGAAATCTGCCCCAAAATTGGCAAAAAAACTACCTGAACTG

ACCGCTTGTCAGCAACAATTGTTTGAACAGATTAGCCTTGAGCCGATCAGCGTTGATGATCTTGCCAAAGCAACAGATAT

GGCGGTAGAAACCGCATTAATTGAGCTGTTAAATTTGGAGTTGTTGGGTGTTGTGAAGCAGGTGAGAGGGGGGTATGTAA

TCACTTGA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(69-276)

DprA winged helix domain (DprA_WH)

(314-371)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
dprA	Glaesserella parasuis strain SC1401	97.333	100	0.973
dprA	Haemophilus influenzae Rd KW20	52.819	89.867	0.475
dprA	Vibrio campbellii strain DS40M4	47.453	99.467	0.472
dprA	Vibrio cholerae strain A1552	44.149	100	0.443
dprA	Legionella pneumophila strain ERS1305867	38.095	100	0.384
dprA	Neisseria gonorrhoeae MS11	43.175	84	0.363

Detailed information NTG0814099