Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   RW107_RS21375 Genome accession   NZ_CP136257
Coordinates   4144564..4145766 (-) Length   400 a.a.
NCBI ID   WP_041850281.1    Uniprot ID   -
Organism   Bacillus subtilis strain A9     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4139564..4150766
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RW107_RS21350 (RW107_21350) rocE 4139796..4141199 (-) 1404 WP_003242721.1 amino acid permease -
  RW107_RS21355 (RW107_21355) rocD 4141422..4142627 (-) 1206 WP_047183487.1 ornithine aminotransferase -
  RW107_RS21360 (RW107_21360) rocR 4142868..4144253 (+) 1386 WP_041850282.1 arginine utilization regulatory protein RocR -
  RW107_RS21365 (RW107_21365) - 4144235..4144396 (-) 162 Protein_4165 ATP-binding protein -
  RW107_RS21370 (RW107_21370) - 4144415..4144544 (-) 130 Protein_4166 hypothetical protein -
  RW107_RS21375 (RW107_21375) htrA 4144564..4145766 (-) 1203 WP_041850281.1 serine protease HtrC Regulator
  RW107_RS21380 (RW107_21380) vicX 4145848..4146642 (-) 795 WP_003226939.1 MBL fold metallo-hydrolase Regulator
  RW107_RS21385 (RW107_21385) walI 4146664..4147506 (-) 843 WP_003244037.1 WalRK two-component regulatory system regulator WalI -
  RW107_RS21390 (RW107_21390) walH 4147493..4148860 (-) 1368 WP_041850604.1 WalRK two-component regulatory system regulator WalH -
  RW107_RS21395 (RW107_21395) walK 4148850..4150685 (-) 1836 WP_009968432.1 cell wall metabolism sensor histidine kinase WalK -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 42760.53 Da        Isoelectric Point: 5.3441

>NTDB_id=814099 RW107_RS21375 WP_041850281.1 4144564..4145766(-) (htrA) [Bacillus subtilis strain A9]
MVDYEREEEHTTPEQPKRSKKGYFLSSLIGVIVGAVLMAFIMPYLSNEGLDTGALDQQQNNNGRESIRTVNVSVNNAVTK
IVSNVSPAVVGVVNIQKSDIWGESGEAGSGSGVIYKKNDNSAYVVTNHHVIEGASQIEISLKDGSRISAELVGSDQLMDL
AVLRVKSNKIKAVADFGNSDKVKSGEPVIAIGNPLGLEFAGSVTQGVISGTERAIPVDSNGDGQPDWNAEVLQTDAAINP
GNSGGALLNMDGKVIGINSMKIAESAVEGIGLSIPSKLVIPVIEDLERYGKVKRPFLGIEMKSLSDIASYHWDETLKLPK
NVTNGAVVMGVDAFSPAGKAGLKELDVITEFDGYKVNDIVDLRKRLYQKKVGDRVKVKFYRGGKEKSVDIKLSSADQLGS

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=814099 RW107_RS21375 WP_041850281.1 4144564..4145766(-) (htrA) [Bacillus subtilis strain A9]
ATGGTGGATTACGAACGTGAGGAAGAACATACTACTCCTGAACAGCCAAAGAGAAGCAAAAAAGGATATTTTCTTTCGAG
TCTGATTGGCGTGATTGTCGGTGCCGTATTAATGGCGTTTATCATGCCGTACCTTTCAAATGAAGGGCTGGATACAGGCG
CCTTAGATCAGCAGCAAAACAACAATGGCCGGGAATCAATCAGGACGGTAAATGTCAGTGTCAACAATGCCGTCACCAAG
ATTGTCAGCAATGTGTCGCCCGCCGTTGTCGGTGTTGTGAACATCCAAAAATCAGATATTTGGGGAGAGAGCGGCGAGGC
TGGAAGCGGCTCAGGCGTCATCTATAAGAAAAATGACAACTCCGCTTATGTCGTGACCAACCATCATGTCATCGAAGGCG
CTTCCCAAATTGAAATCAGCTTGAAAGACGGCTCACGCATATCAGCTGAACTTGTCGGCAGCGACCAGCTGATGGACCTT
GCCGTTTTACGGGTGAAAAGCAATAAAATTAAAGCAGTCGCCGATTTCGGAAATTCAGATAAAGTGAAGTCTGGCGAGCC
GGTTATTGCGATCGGGAATCCGTTAGGCCTTGAGTTTGCAGGTTCTGTCACACAAGGCGTCATCTCAGGTACGGAGAGGG
CGATCCCAGTGGATTCAAACGGTGATGGACAGCCTGACTGGAACGCAGAAGTCCTGCAAACAGATGCGGCCATTAACCCT
GGGAACAGCGGCGGTGCTTTGTTAAATATGGATGGGAAGGTCATTGGCATCAATTCAATGAAAATTGCCGAGTCGGCGGT
TGAAGGGATTGGCCTGTCGATTCCATCTAAGCTCGTGATCCCTGTGATAGAGGATTTAGAGAGATACGGAAAGGTCAAAC
GCCCGTTCCTTGGGATTGAGATGAAATCGCTAAGCGACATCGCAAGCTATCATTGGGATGAAACATTAAAGCTTCCTAAG
AATGTTACCAATGGAGCGGTTGTGATGGGTGTAGACGCCTTTTCACCTGCCGGAAAAGCGGGGCTGAAGGAACTGGATGT
CATCACGGAATTTGACGGATACAAAGTAAATGATATTGTTGACCTGCGAAAACGGCTTTATCAGAAAAAAGTCGGTGACC
GGGTGAAGGTGAAGTTTTACCGCGGCGGAAAAGAAAAATCTGTAGACATCAAGCTGTCCTCCGCAGACCAATTAGGCAGT
TAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(295-392)

Peptidase family M50 (Peptidase_M50)

(183-395)

Trypsin-like peptidase domain (Trypsin_2)

(110-257)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

43.577

99.25

0.433
  htrA Streptococcus gordonii str. Challis substr. CH1

41.294

100

0.415
  htrA Streptococcus mitis NCTC 12261

43.005

96.5

0.415
  htrA Streptococcus pneumoniae TIGR4

45.152

82.5

0.373
  htrA Streptococcus pneumoniae D39

45.152

82.5

0.373
  htrA Streptococcus pneumoniae Rx1

45.152

82.5

0.373
  htrA Streptococcus pneumoniae R6

45.152

82.5

0.373