Detailed information NTG0813806

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: QBE57_RS08815
• Genome accession: NZ_CP121670
• Coordinates: 1785511..1786707 (-)
• Length: 398 a.a.
• NCBI ID: WP_012028059.1
• Uniprot ID: D5AF49
• Organism: Streptococcus suis strain HBXY-SL
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1780511..1791707

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QBE57_RS08790	-	1780634..1780837 (-)	204	WP_011922523.1	DUF951 domain-containing protein	-
QBE57_RS08795	-	1780847..1781728 (-)	882	WP_011921629.1	diacylglycerol/lipid kinase family protein	-
QBE57_RS08800	dnaN	1781820..1782956 (-)	1137	WP_004194538.1	DNA polymerase III subunit beta	-
QBE57_RS08805	dnaA	1783110..1784483 (-)	1374	WP_011921628.1	chromosomal replication initiator protein DnaA	-
QBE57_RS08810	spo0J	1784686..1785450 (-)	765	WP_012775418.1	ParB/RepB/Spo0J family partition protein	Regulator
QBE57_RS08815	htrA	1785511..1786707 (-)	1197	WP_012028059.1	S1C family serine protease	Regulator
QBE57_RS08820	rlmH	1786881..1787360 (+)	480	WP_012028058.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
QBE57_RS08825	-	1787385..1788068 (+)	684	WP_012775416.1	YoaK family protein	-
QBE57_RS08845	-	1788469..1791048 (-)	2580	WP_012028056.1	YfhO family protein	-

Sequence

Protein

• Length: 398 a.a.
• Molecular weight: 41866.92 Da
• Isoelectric Point: 4.6543

>NTDB_id=813806 QBE57_RS08815 WP_012028059.1 1785511..1786707(-) (htrA) [Streptococcus suis strain HBXY-SL]
MERIPYMKKYLKFAILFVIGFFGGLIGALSASFFQPQVQQANSAITSVSNVQYNNETSTTKAVEKVQNAVVSVINYQKSA
NNSLGVIFGNIESSDELAVAGEGSGVIYKKYGQYAYIVTNTHVINNAEKIDILLASGEKISGELVGSDTYSDIAVIKISA
DKVTAVAEFADSDTIKVGETAIAIGSPLGSVYANTVTQGIISSLSRTVTSQSKDGQTISTNAIQTDTAINPGNSGGPLIN
TQGQVIGITSSKITSSSANSSGVAVEGLGFAIPANDAVAIINQLEKTGQVSRPALGVHMVNLTTLSTSQLEKAGLSNTEL
TSGVVIVSTQSGLPADGKLETFDVITEIDGEAIQNKSDLQSALYKHQIGDTITVTYYRNNQKQTVDIKLTHSTEELSE

Nucleotide

• Length: 1197 bp

>NTDB_id=813806 QBE57_RS08815 WP_012028059.1 1785511..1786707(-) (htrA) [Streptococcus suis strain HBXY-SL]
ATGGAAAGGATTCCTTATATGAAAAAATATTTGAAATTTGCGATTTTATTTGTAATTGGATTTTTTGGGGGTCTTATCGG
GGCCTTGTCAGCCTCTTTCTTCCAGCCACAGGTGCAACAAGCAAATTCTGCTATCACTAGTGTCAGCAATGTTCAATATA
ATAATGAAACTTCCACCACAAAAGCTGTAGAGAAAGTACAAAATGCTGTTGTGTCTGTTATTAATTACCAAAAATCAGCC
AACAATAGTCTTGGTGTTATCTTTGGAAATATTGAATCATCTGACGAACTAGCTGTTGCTGGAGAGGGGTCTGGGGTTAT
CTATAAAAAATATGGTCAATATGCCTATATTGTGACAAATACGCATGTTATTAATAACGCAGAAAAGATTGATATCCTTT
TAGCATCTGGAGAAAAAATTAGCGGTGAACTTGTTGGTTCCGATACATATTCTGATATAGCTGTTATAAAAATATCAGCA
GATAAAGTCACTGCTGTTGCTGAATTTGCTGATTCCGATACAATTAAAGTTGGAGAAACTGCTATCGCAATTGGTAGTCC
TCTAGGTAGCGTCTACGCCAATACAGTTACCCAGGGTATTATTTCTAGCTTAAGTCGGACAGTTACTTCACAATCAAAAG
ATGGACAAACAATCTCAACTAACGCTATTCAAACTGATACAGCTATCAACCCTGGAAACTCTGGCGGACCGTTAATCAAT
ACCCAAGGACAAGTGATAGGCATTACCTCTAGCAAAATTACCTCAAGTTCTGCAAATAGCTCAGGCGTGGCTGTAGAAGG
GTTGGGATTTGCTATTCCTGCAAATGATGCCGTAGCTATTATCAATCAGCTTGAAAAAACTGGACAAGTTAGCCGACCTG
CTCTTGGAGTTCATATGGTTAACTTGACGACCTTGTCAACTAGTCAATTAGAAAAAGCTGGATTATCAAATACGGAATTA
ACATCCGGTGTAGTAATTGTCTCTACACAAAGTGGGCTACCTGCAGATGGAAAATTAGAAACTTTTGATGTTATTACTGA
GATTGACGGAGAAGCTATTCAAAATAAGAGTGACCTCCAGAGCGCTCTCTACAAACATCAAATTGGAGATACAATCACTG
TAACTTATTACCGCAATAATCAGAAACAAACTGTTGACATTAAGTTGACACATTCTACAGAAGAACTTAGCGAATAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (103-248)

• PDZ domain (PDZ_2) (293-389)

3D structure

• AlphaFold DB: D5AF49

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	59.194	99.749	0.59
htrA	Streptococcus gordonii str. Challis substr. CH1	58.987	99.246	0.585
htrA	Streptococcus pneumoniae D39	57.252	98.744	0.565
htrA	Streptococcus pneumoniae TIGR4	57.252	98.744	0.565
htrA	Streptococcus mitis NCTC 12261	57.252	98.744	0.565
htrA	Streptococcus pneumoniae R6	57.252	98.744	0.565
htrA	Streptococcus pneumoniae Rx1	57.252	98.744	0.565