Detailed information NTG0812847

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: QA712_RS02135
• Genome accession: NZ_CP121539
• Coordinates: 308776..310923 (-)
• Length: 715 a.a.
• NCBI ID: WP_372757465.1
• Uniprot ID: -
• Organism: Lactococcus lactis strain MA5
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 303776..315923

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QA712_RS02095 (QA712_02075)	-	303968..304069 (+)	102	WP_134798151.1	type I toxin-antitoxin system Fst family toxin	-
QA712_RS02100 (QA712_02080)	-	304248..304442 (-)	195	WP_372757455.1	hypothetical protein	-
QA712_RS02105 (QA712_02085)	-	305499..305963 (-)	465	WP_046125146.1	hypothetical protein	-
QA712_RS02110 (QA712_02090)	-	305982..306215 (-)	234	WP_372757457.1	Blp family class II bacteriocin	-
QA712_RS02115 (QA712_02095)	-	306241..306450 (-)	210	WP_372757459.1	Blp family class II bacteriocin	-
QA712_RS02120 (QA712_02100)	-	306725..307021 (-)	297	WP_015081787.1	bacteriocin immunity protein	-
QA712_RS02125 (QA712_02105)	-	307036..307263 (-)	228	WP_372757461.1	lactococcin family bacteriocin	-
QA712_RS02130 (QA712_02110)	-	307337..308761 (-)	1425	WP_372757463.1	HlyD family secretion protein	-
QA712_RS02135 (QA712_02115)	comA	308776..310923 (-)	2148	WP_372757465.1	peptide cleavage/export ABC transporter	Regulator
QA712_RS02140 (QA712_02120)	-	311340..312281 (-)	942	WP_334202109.1	hypothetical protein	-
QA712_RS02145 (QA712_02125)	-	312318..312959 (-)	642	WP_334202108.1	type II restriction endonuclease	-
QA712_RS02150 (QA712_02130)	-	313208..314673 (+)	1466	Protein_295	Y-family DNA polymerase	-
QA712_RS02155 (QA712_02135)	-	314633..315013 (+)	381	WP_372757467.1	hypothetical protein	-
QA712_RS02160 (QA712_02140)	-	315058..315285 (-)	228	WP_003131208.1	hypothetical protein	-
QA712_RS02165 (QA712_02145)	-	315413..315568 (-)	156	WP_372757469.1	hypothetical protein	-

Sequence

Protein

• Length: 715 a.a.
• Molecular weight: 79772.24 Da
• Isoelectric Point: 7.5797

>NTDB_id=812847 QA712_RS02135 WP_372757465.1 308776..310923(-) (comA) [Lactococcus lactis strain MA5]
MKFKKKNYTSQVDEMDCGCAALSMILKSYGTEKSLASLRLLAGTTIEGTSALGIKKAAEELDFSVQALRTDASLFDMKEV
PYPFIAHVIKNQKYPHYYVITGANKNSVFIADPDPTVKMTKLSKEVFLSEWTGISLFLSPTPAYHPTKEKASSLLSFIPI
ITRQKKVILNIVVASLIVTLINILGSYYLQSMIDSYIPNALMGTLGIISVGLLLTYIIQQVLEFAKTFLLNVLSQRLAID
VILSYIRHIFQLPMSFFSTRRTGEITSRFSDASSILDAIASTILSLFLDLTIVLMTGLILGLQNMQLFLLVLLAIPLYIV
VIIIFTPLFEKQNHEVMQTNAVLNSSIIEDINGIETIKALASEQERYQKIDYEFASYLKKAFTLQKSEAIQGLIKAIIQL
TLSVTILWFGATLVISQKITLGQLITFNALLSYFTNPITNIINLQTKLQKARVANERLNEVYLVPSEFEEKKTELSLSHF
NLNMSDISYQYGFGRKVLSEIELSIKENEKLTIVGMSGSGKSTLVKLLVNFFQPTSGTITLGGIDLQQFDKHQLRRLINY
LPQQPYIFTGSILDNLLLGANENASQEEILKAVELAEIRADIEQMQLGYQTELSSDASSLSGGQKQRIALARALLSPAKI
LILDEATSNLDMITEKKILKNLLPLDKTIIFIAHRLSVAEMSHRIIVVDQGKVIETGSHVDLLAQNGFYGQLYHN

Nucleotide

• Length: 2148 bp

>NTDB_id=812847 QA712_RS02135 WP_372757465.1 308776..310923(-) (comA) [Lactococcus lactis strain MA5]
ATGAAATTTAAAAAGAAAAATTATACCTCACAAGTAGATGAAATGGATTGTGGTTGTGCTGCTTTATCGATGATTTTAAA
ATCTTACGGGACAGAAAAATCTCTCGCTTCATTGCGTTTACTTGCTGGTACAACAATCGAAGGGACATCCGCTTTGGGGA
TAAAAAAAGCAGCTGAAGAGTTAGATTTTTCAGTCCAAGCCCTAAGAACAGATGCAAGCCTCTTTGATATGAAGGAAGTC
CCTTATCCTTTTATTGCTCATGTTATTAAAAACCAAAAGTATCCACACTACTATGTGATAACAGGCGCAAATAAAAACTC
GGTATTCATTGCTGATCCTGACCCAACCGTTAAAATGACAAAATTATCAAAAGAAGTTTTTTTATCGGAATGGACAGGCA
TTAGTTTATTTCTTTCGCCTACACCAGCTTATCATCCCACTAAAGAAAAAGCTTCTTCATTATTATCTTTTATCCCAATT
ATCACCCGTCAAAAGAAAGTTATTCTTAACATTGTTGTTGCTTCACTCATTGTGACACTGATTAATATTCTAGGGTCTTA
CTATCTCCAGAGCATGATTGACAGCTACATTCCGAATGCCTTAATGGGAACTTTAGGGATTATCTCAGTAGGACTATTAT
TGACTTATATTATCCAACAAGTCTTAGAGTTTGCTAAAACTTTCTTACTGAATGTTCTTTCTCAAAGATTAGCCATTGAT
GTCATTCTTTCGTATATTAGACACATTTTCCAACTTCCGATGTCTTTCTTTTCGACTAGAAGAACAGGGGAAATTACCAG
TCGGTTTTCTGATGCTAGTTCTATTTTAGATGCTATTGCTTCAACGATTCTCTCCCTCTTTTTAGATTTGACGATTGTCC
TCATGACAGGACTAATTTTAGGCCTTCAAAATATGCAACTCTTTCTTCTCGTTCTTTTGGCAATCCCACTTTATATTGTT
GTTATTATTATTTTTACGCCCCTTTTTGAAAAACAAAACCATGAAGTCATGCAGACCAATGCCGTCTTAAACTCCTCAAT
TATTGAAGATATCAATGGGATTGAAACTATAAAGGCACTTGCCAGTGAACAAGAAAGATATCAAAAAATTGACTACGAAT
TTGCAAGTTATCTAAAAAAGGCTTTCACTTTACAAAAATCAGAAGCTATTCAAGGCTTAATTAAAGCAATTATACAACTA
ACATTGAGTGTCACCATTTTATGGTTTGGTGCCACATTAGTAATAAGTCAAAAAATTACGCTCGGACAATTGATTACTTT
TAATGCCCTGCTTTCTTACTTTACAAATCCAATTACTAATATCATTAACCTTCAAACAAAACTCCAAAAGGCAAGGGTAG
CCAATGAACGATTAAATGAGGTCTATCTTGTACCCAGTGAATTTGAGGAAAAGAAAACAGAACTGTCCCTCTCACATTTT
AACTTAAACATGTCCGATATTTCATATCAATATGGTTTTGGCAGAAAAGTCTTATCTGAGATAGAACTCTCTATTAAAGA
AAATGAAAAATTGACTATTGTGGGCATGAGTGGTTCAGGAAAGAGTACCCTTGTTAAATTATTGGTCAACTTCTTTCAAC
CCACTTCTGGCACCATCACTTTAGGTGGAATTGACCTGCAACAGTTTGATAAACACCAACTCCGAAGATTAATCAACTAT
CTTCCCCAACAACCTTATATTTTTACTGGTTCAATTTTAGATAATCTACTTCTAGGAGCTAATGAGAATGCATCACAAGA
AGAGATTCTTAAAGCGGTGGAATTGGCAGAAATCCGTGCAGATATTGAACAAATGCAGTTGGGCTATCAGACCGAACTTT
CAAGTGATGCAAGTAGTCTATCGGGGGGACAAAAACAACGCATTGCTTTAGCTCGTGCGCTCCTTTCCCCTGCCAAAATC
CTCATTTTAGATGAAGCAACCAGTAACCTTGATATGATTACAGAGAAGAAAATATTAAAGAACTTGTTGCCCTTGGATAA
AACCATTATTTTCATTGCTCACCGCCTCTCTGTGGCGGAAATGAGTCATCGAATTATTGTTGTCGATCAAGGAAAAGTGA
TAGAGACTGGCTCACATGTTGACCTGCTTGCACAAAATGGCTTTTATGGCCAACTTTACCATAACTGA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (498-648)

• Peptidase C39 family (Peptidase_C39) (6-142)

• ABC transporter transmembrane region (ABC_membrane) (169-437)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus gordonii str. Challis substr. CH1	61.625	99.86	0.615
comA	Streptococcus mitis NCTC 12261	60.504	99.86	0.604
comA	Streptococcus mitis SK321	60.224	99.86	0.601
comA	Streptococcus pneumoniae R6	60.084	99.86	0.6
comA	Streptococcus pneumoniae Rx1	60.084	99.86	0.6
comA	Streptococcus pneumoniae D39	60.084	99.86	0.6
comA	Streptococcus pneumoniae TIGR4	59.804	99.86	0.597
comA/nlmT	Streptococcus mutans UA159	58.217	100	0.585