Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   P8P68_RS09290 Genome accession   NZ_CP121467
Coordinates   1920726..1922627 (+) Length   633 a.a.
NCBI ID   WP_278275926.1    Uniprot ID   A0AAX3TJA6
Organism   Streptococcus sp. D7B5     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1915726..1927627
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P8P68_RS09275 (P8P68_09275) fmt 1917732..1918667 (+) 936 WP_278275924.1 methionyl-tRNA formyltransferase -
  P8P68_RS09280 (P8P68_09280) rsmB 1918660..1919973 (+) 1314 WP_278275925.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  P8P68_RS09285 (P8P68_09285) - 1919989..1920729 (+) 741 WP_000401527.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  P8P68_RS09290 (P8P68_09290) stkP 1920726..1922627 (+) 1902 WP_278275926.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  P8P68_RS09295 (P8P68_09295) - 1922715..1923473 (+) 759 WP_000344542.1 threonine/serine exporter family protein -
  P8P68_RS09300 (P8P68_09300) - 1923475..1923930 (+) 456 WP_044021233.1 threonine/serine exporter family protein -
  P8P68_RS09305 (P8P68_09305) - 1924049..1925221 (+) 1173 WP_278276311.1 hydroxymethylglutaryl-CoA synthase -
  P8P68_RS09310 (P8P68_09310) - 1925221..1926495 (+) 1275 WP_278275927.1 hydroxymethylglutaryl-CoA reductase, degradative -
  P8P68_RS09315 (P8P68_09315) - 1926647..1927612 (-) 966 WP_000225979.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 633 a.a.        Molecular weight: 68843.06 Da        Isoelectric Point: 8.9709

>NTDB_id=812266 P8P68_RS09290 WP_278275926.1 1920726..1922627(+) (stkP) [Streptococcus sp. D7B5]
MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATFQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPSVP
QALENVVIKATAKKLSDRYQSVSEMYVDLSTSLSYNRRNEPKLVFDDASKADTKTLPKVPQSTLTSIPKAPAQEERPQPK
KPTQPVAEPAPAPKPAKKRKFKARYMILLASLLLVAASLVWILSRTPATIAIPDVAGQTVAEAKEALKKSKFEAGEEKSE
ASDTVAEGRVIRTDPEAGSGRKEGTKVNLIVSSGKQSFQLSNYVGRKYTEVVAELKEKKVPENLIKMEEEESSESEPGTV
LRQTPASGSTYDLSKATTITLTVAKKVTSVSMPNYIGSSLEFTKNNLTQIVGVKEANIEVVEVSTAPEGTAEGTVVSQTP
RAGEQVDLASTRIKLSIYKPKTPPSTSSSNPAQRGNQGSTTTPNQGNQQGNQQGNTPSSSSSNSEGTHESSRD

Nucleotide


Download         Length: 1902 bp        

>NTDB_id=812266 P8P68_RS09290 WP_278275926.1 1920726..1922627(+) (stkP) [Streptococcus sp. D7B5]
ATGATCCAAATCGGCAAGATTTTTGCCGGGCGGTATCGGATTGTCAAGCAGATTGGTCGAGGAGGCATGGCAGATGTATA
CTTGGCCAAGGATTTGATCCTAGACGGGGAAGAAGTGGCAGTGAAGGTCCTGAGGACCAACTACCAGACGGACCCGATTG
CTGTGGCACGTTTCCAGCGGGAAGCGAGAGCCATGGCGGATCTGGACCATCCTCATATCGTTCGGATAACAGATATTGGT
GAGGAAGACGGTCAACAGTACCTGGCTATGGAATACGTAGCAGGCCTTGACCTCAAGCGTTATATCAAAGAACACTATCC
TCTTTCAAATGAAGAAGCGGTTCGGATTATGGGGCAAATCCTCTTGGCCATGCGCTTAGCCCATACTCGAGGAATCGTTC
ACCGGGATTTGAAACCTCAAAATATCCTCTTGACACCTGACGGCACAGCTAAGGTCACGGACTTTGGGATTGCCGTAGCC
TTTGCGGAGACTAGTCTGACCCAGACAAACTCAATGTTAGGCTCTGTTCATTATTTGTCACCTGAGCAAGCGCGTGGTTC
TAAAGCTACTTTCCAGAGCGATATCTATGCGATGGGGATTATCTTCTATGAAATGCTGACGGGACATATCCCTTATGATG
GGGATAGCGCGGTGACCATCGCCCTCCAGCATTTCCAGAAGCCACTTCCGTCCGTCATAGCTGAAAACCCATCTGTCCCT
CAGGCTTTAGAAAATGTTGTCATCAAGGCAACTGCTAAGAAGCTGTCAGATCGTTATCAGTCTGTTTCAGAAATGTATGT
GGACTTGTCAACTAGCTTGTCTTATAATCGTCGCAATGAACCGAAGCTGGTCTTTGACGATGCGAGTAAGGCAGACACTA
AGACTTTACCTAAAGTCCCACAAAGTACACTGACATCGATTCCTAAAGCTCCGGCGCAAGAAGAACGCCCTCAGCCAAAG
AAACCAACTCAACCAGTGGCAGAACCGGCTCCAGCGCCAAAACCAGCCAAGAAACGGAAGTTTAAGGCTCGCTATATGAT
TCTTTTGGCCAGTCTTCTATTGGTTGCAGCCTCTTTGGTTTGGATTTTGTCAAGGACACCAGCAACGATTGCTATTCCTG
ACGTAGCTGGACAAACCGTTGCAGAGGCTAAGGAAGCTCTTAAAAAATCCAAGTTTGAAGCCGGTGAAGAAAAGTCAGAG
GCCAGCGATACCGTAGCAGAAGGACGTGTTATTCGAACGGATCCAGAAGCTGGTAGCGGCCGAAAAGAAGGAACCAAGGT
CAATTTGATTGTTTCTTCTGGTAAGCAATCCTTCCAATTGAGCAATTATGTCGGACGTAAGTATACGGAAGTTGTAGCTG
AACTCAAGGAGAAGAAGGTTCCTGAAAATCTAATCAAGATGGAAGAGGAAGAATCCAGCGAAAGCGAACCTGGAACCGTC
CTCAGACAGACCCCTGCATCGGGTTCGACTTATGATCTCTCAAAAGCTACTACGATTACCTTAACAGTGGCTAAGAAGGT
GACTAGTGTCAGCATGCCGAACTACATTGGTTCAAGTCTCGAGTTTACAAAGAATAACTTGACTCAGATTGTCGGTGTGA
AGGAAGCAAATATTGAGGTTGTAGAAGTATCGACTGCTCCTGAAGGAACGGCAGAAGGAACTGTTGTAAGTCAAACGCCA
AGAGCAGGAGAACAGGTTGATCTTGCAAGTACGCGTATCAAACTTTCTATCTACAAACCAAAAACACCACCATCAACTTC
ATCCTCTAATCCTGCCCAACGTGGAAACCAGGGTTCTACAACCACTCCAAACCAGGGGAACCAACAAGGAAATCAACAAG
GGAACACTCCTTCTAGCAGTTCATCCAATAGTGAAGGAACTCACGAAAGTTCTCGAGATTAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(371-432)

PASTA domain (PASTA)

(441-505)

PASTA domain (PASTA)

(510-579)

Protein kinase domain (Pkinase)

(12-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

78.669

92.575

0.728
  stkP Streptococcus pneumoniae D39

78.328

92.575

0.725
  stkP Streptococcus pneumoniae R6

78.328

92.575

0.725
  stkP Streptococcus pneumoniae Rx1

78.157

92.575

0.724
  pknB Streptococcus mutans UA159

56.326

91.153

0.513
  stkP/pknB Streptococcus salivarius strain HSISS4

52.277

93.681

0.49