Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   P8P68_RS03385 Genome accession   NZ_CP121467
Coordinates   696723..697463 (-) Length   246 a.a.
NCBI ID   WP_042902136.1    Uniprot ID   A0A081R558
Organism   Streptococcus sp. D7B5     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 691723..702463
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P8P68_RS03370 (P8P68_03370) msrB 693266..694204 (-) 939 WP_278276160.1 peptide-methionine (R)-S-oxide reductase MsrB -
  P8P68_RS03375 (P8P68_03375) thrB 694418..695287 (-) 870 WP_278276161.1 homoserine kinase -
  P8P68_RS03380 (P8P68_03380) - 695289..696575 (-) 1287 WP_278276162.1 homoserine dehydrogenase -
  P8P68_RS03385 (P8P68_03385) mecA 696723..697463 (-) 741 WP_042902136.1 adaptor protein MecA Regulator
  P8P68_RS03390 (P8P68_03390) - 697586..699064 (+) 1479 WP_061586872.1 oligosaccharide flippase family protein -
  P8P68_RS03395 (P8P68_03395) - 699111..701639 (-) 2529 WP_278276163.1 MBL fold metallo-hydrolase -

Sequence

Protein


Download         Length: 246 a.a.        Molecular weight: 28525.35 Da        Isoelectric Point: 4.1097

>NTDB_id=812210 P8P68_RS03385 WP_042902136.1 696723..697463(-) (mecA) [Streptococcus sp. D7B5]
MKMKQISDTTLKITMTLDDLMDRGMEIADFLVPQEKTEEFFYAILDELEMPDNFLDSGMLSFRVTPKPDKVDVFVTKSKI
DQNLDFEDLADLPDMEELAQMSPDEFLKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQADKETESKKEPYIYYILRFV
SLADLVAFAKTVNYQMETSELYKMNGHYYLTILVDVENHPSPYPAWLLARMREFADDSDISRSVLQEYGQILINHDAVLG
LQKIRS

Nucleotide


Download         Length: 741 bp        

>NTDB_id=812210 P8P68_RS03385 WP_042902136.1 696723..697463(-) (mecA) [Streptococcus sp. D7B5]
ATGAAGATGAAACAAATTAGTGATACAACACTGAAAATCACAATGACTTTAGATGATTTGATGGACCGAGGAATGGAGAT
TGCAGACTTTCTCGTTCCTCAGGAAAAAACTGAAGAGTTTTTCTATGCTATTTTAGATGAGTTAGAGATGCCAGACAATT
TCTTGGATAGTGGCATGCTGAGTTTCCGCGTGACGCCAAAACCTGATAAGGTGGACGTCTTTGTGACCAAGTCCAAGATT
GACCAGAATCTGGATTTTGAAGATTTGGCGGATCTACCAGACATGGAAGAATTAGCCCAAATGTCGCCGGATGAATTTCT
CAAAACCTTGGAAAAGAGCATTGCAGATAAAACCAAGGACGATATTGAGGCCATCCAATCTCTAGAGCAGGTCGAAGCAA
AGGAAGAAGAGCAAGAGCAGGCAGACAAGGAGACTGAGAGTAAGAAAGAACCTTATATCTACTATATCCTGCGCTTTGTA
AGCCTTGCTGACTTAGTTGCTTTTGCAAAGACGGTTAACTACCAGATGGAAACCTCTGAACTCTATAAGATGAATGGACA
CTATTATTTGACAATCTTAGTCGATGTAGAAAATCATCCAAGTCCATATCCAGCCTGGCTCTTGGCTCGTATGCGTGAGT
TTGCAGACGACAGTGACATCAGTCGTTCAGTCTTGCAAGAGTATGGGCAAATCTTGATCAATCACGATGCAGTTCTCGGT
CTGCAAAAGATTCGTTCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-238)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A081R558

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

90.574

99.187

0.898
  mecA Streptococcus pneumoniae D39

90.574

99.187

0.898
  mecA Streptococcus pneumoniae R6

90.574

99.187

0.898
  mecA Streptococcus pneumoniae TIGR4

90.164

99.187

0.894
  mecA Streptococcus thermophilus LMD-9

47.222

100

0.484
  mecA Streptococcus mutans UA159

48.361

99.187

0.48
  mecA Streptococcus thermophilus LMG 18311

46.825

100

0.48