Detailed information
Bioinformatically predicted
Overview
| Name | comA | Type | Regulator |
| Locus tag | P8R55_RS03450 | Genome accession | NZ_CP121285 |
| Coordinates | 718777..720936 (+) | Length | 719 a.a. |
| NCBI ID | WP_339961485.1 | Uniprot ID | - |
| Organism | Lactobacillus johnsonii strain L16 | ||
| Function | processing and transport of ComC (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 713766..748899 | 718777..720936 | within | 0 |
| IScluster/Tn | 717406..718454 | 718777..720936 | flank | 323 |
Gene organization within MGE regions
Location: 713766..748899
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| P8R55_RS03425 (P8R55_03405) | - | 713766..713918 (+) | 153 | WP_004896917.1 | hypothetical protein | - |
| P8R55_RS03430 (P8R55_03410) | - | 713945..715228 (+) | 1284 | WP_407325542.1 | sensor histidine kinase | - |
| P8R55_RS03435 (P8R55_03415) | - | 715372..716529 (+) | 1158 | WP_127835553.1 | RNA-guided endonuclease TnpB family protein | - |
| P8R55_RS03440 (P8R55_03420) | - | 716727..717398 (+) | 672 | WP_407325543.1 | LytR/AlgR family response regulator transcription factor | - |
| P8R55_RS03445 (P8R55_03425) | - | 717406..718454 (-) | 1049 | Protein_648 | IS30 family transposase | - |
| P8R55_RS03450 (P8R55_03430) | comA | 718777..720936 (+) | 2160 | WP_339961485.1 | peptide cleavage/export ABC transporter | Regulator |
| P8R55_RS03455 (P8R55_03435) | - | 720947..721540 (+) | 594 | WP_014567254.1 | hypothetical protein | - |
| P8R55_RS03460 (P8R55_03440) | - | 721690..721884 (+) | 195 | WP_004896927.1 | hypothetical protein | - |
| P8R55_RS03465 (P8R55_03445) | - | 721997..722287 (+) | 291 | WP_011161719.1 | bacteriocin immunity protein | - |
| P8R55_RS03470 (P8R55_03450) | - | 722570..722845 (+) | 276 | WP_014567255.1 | hypothetical protein | - |
| P8R55_RS03475 (P8R55_03455) | - | 723050..723280 (+) | 231 | WP_407325544.1 | hypothetical protein | - |
| P8R55_RS03480 (P8R55_03460) | - | 723403..723717 (+) | 315 | WP_004896933.1 | bacteriocin immunity protein | - |
| P8R55_RS03485 (P8R55_03465) | - | 723720..724004 (+) | 285 | WP_004896934.1 | hypothetical protein | - |
| P8R55_RS03490 (P8R55_03470) | - | 724068..726899 (+) | 2832 | WP_014567257.1 | cation-transporting P-type ATPase | - |
| P8R55_RS03495 (P8R55_03475) | - | 726971..727819 (+) | 849 | WP_014567258.1 | patatin family protein | - |
| P8R55_RS03500 (P8R55_03480) | - | 727920..729413 (+) | 1494 | WP_407325545.1 | ABC transporter substrate-binding protein/permease | - |
| P8R55_RS03505 (P8R55_03485) | - | 729400..730131 (+) | 732 | WP_004896938.1 | amino acid ABC transporter ATP-binding protein | - |
| P8R55_RS03510 (P8R55_03490) | - | 730227..730748 (+) | 522 | WP_004896939.1 | GNAT family N-acetyltransferase | - |
| P8R55_RS03515 (P8R55_03495) | - | 730866..731735 (+) | 870 | WP_004896940.1 | phosphate ABC transporter substrate-binding protein | - |
| P8R55_RS03520 (P8R55_03500) | pstC | 731752..732744 (+) | 993 | WP_011161729.1 | phosphate ABC transporter permease subunit PstC | - |
| P8R55_RS03525 (P8R55_03505) | pstA | 732744..733634 (+) | 891 | WP_004896942.1 | phosphate ABC transporter permease PstA | - |
| P8R55_RS03530 (P8R55_03510) | pstB | 733645..734445 (+) | 801 | WP_004896943.1 | phosphate ABC transporter ATP-binding protein PstB | - |
| P8R55_RS03535 (P8R55_03515) | pstB | 734456..735211 (+) | 756 | WP_004896944.1 | phosphate ABC transporter ATP-binding protein PstB | - |
| P8R55_RS03540 (P8R55_03520) | phoU | 735228..735911 (+) | 684 | WP_004896945.1 | phosphate signaling complex protein PhoU | - |
| P8R55_RS03545 (P8R55_03525) | - | 735930..736376 (+) | 447 | WP_004896946.1 | GNAT family N-acetyltransferase | - |
| P8R55_RS03550 (P8R55_03530) | ltrA | 736981..738276 (+) | 1296 | WP_004897912.1 | group II intron reverse transcriptase/maturase | - |
| P8R55_RS03555 (P8R55_03535) | - | 738459..739997 (+) | 1539 | WP_407325546.1 | YfcC family protein | - |
| P8R55_RS03560 (P8R55_03540) | - | 740081..740548 (+) | 468 | WP_004895429.1 | DNA starvation/stationary phase protection protein | - |
| P8R55_RS03565 (P8R55_03545) | rbsK | 740638..741564 (+) | 927 | WP_004896948.1 | ribokinase | - |
| P8R55_RS03570 (P8R55_03550) | rpiA | 741564..742262 (+) | 699 | WP_014567261.1 | ribose-5-phosphate isomerase RpiA | - |
| P8R55_RS03575 (P8R55_03555) | - | 742328..743140 (+) | 813 | WP_014567262.1 | helix-turn-helix domain-containing protein | - |
| P8R55_RS03580 (P8R55_03560) | - | 743297..744796 (+) | 1500 | WP_014567263.1 | protein kinase domain-containing protein | - |
| P8R55_RS03585 (P8R55_03565) | - | 744789..745133 (+) | 345 | WP_407325547.1 | hypothetical protein | - |
| P8R55_RS03590 (P8R55_03570) | - | 745234..746283 (+) | 1050 | WP_407325548.1 | IS30-like element ISLjo1 family transposase | - |
| P8R55_RS03595 (P8R55_03575) | - | 746312..747103 (+) | 792 | WP_407325549.1 | lanthionine synthetase C family protein | - |
| P8R55_RS03600 (P8R55_03580) | - | 747128..747256 (+) | 129 | WP_407325550.1 | hypothetical protein | - |
| P8R55_RS03605 (P8R55_03585) | - | 747325..748899 (+) | 1575 | WP_014567265.1 | ABC transporter ATP-binding protein | - |
Sequence
Protein
Download Length: 719 a.a. Molecular weight: 81177.50 Da Isoelectric Point: 7.4684
>NTDB_id=811606 P8R55_RS03450 WP_339961485.1 718777..720936(+) (comA) [Lactobacillus johnsonii strain L16]
MLFKYKSVYVPQVDEMDCGVACLAMILKQYQSRVSLAHLRREARTNLEGTTALGLVKTAQKFNFKTEAVKADMSLFNEDT
IQYPFIVHVLKQGELLHYYVVLKNTKNYLVIADPDPSVGIIKMPKDKFAQEWTGIALFMVPNEDFEPIKEKKNNLWSLFP
YMFKQKRLMINIILAALLMTIISICSSYFVQGIIDTYIPDGTYQTLSILAVGLLIAYIFNSIFSYGQNFLLNVLGQRLSI
DLNLQYIRHIFELPMEFFVTRRTGEITSRFSDASRIIDALASTVISLFLDLAIVIVMGLVLAAQNMTLFGITLLALPVYA
VVILGFTKKFEKLNDEQMESNAVLSSSVIEDIQGIETIKALNSEDTRYRRIDSQFVNYLKKSFKYSKAESLQTALKTFIQ
LSLNVIILWVGARVVMQGQMSIGQLMTFNALLSYFIDPLQNIINLQPRLQSASVAQNRLNEVYQVQSEFNADTSIQNSAA
LERMIEYKHVDYRYGYGTDVLKNINLKIKPDEKLAIVGMSGSGKSTMVKLLVDFFSPSKGEVTLNGHATSEVNKHTLRSY
VNYVPQTPYIFSGTVKKNLLLGCRPDISEEDVIKACQIAGIDQEIASLPLQFETKLDENAKILSGGQKQRLTIARALLSP
AKVFIFDEVTSGLDTITEKRVVDNLMKLKDKTIIFIAHRLAIAERADKVVVIDQGQIVEEGSHEELMEQHGFYYDLVKG
MLFKYKSVYVPQVDEMDCGVACLAMILKQYQSRVSLAHLRREARTNLEGTTALGLVKTAQKFNFKTEAVKADMSLFNEDT
IQYPFIVHVLKQGELLHYYVVLKNTKNYLVIADPDPSVGIIKMPKDKFAQEWTGIALFMVPNEDFEPIKEKKNNLWSLFP
YMFKQKRLMINIILAALLMTIISICSSYFVQGIIDTYIPDGTYQTLSILAVGLLIAYIFNSIFSYGQNFLLNVLGQRLSI
DLNLQYIRHIFELPMEFFVTRRTGEITSRFSDASRIIDALASTVISLFLDLAIVIVMGLVLAAQNMTLFGITLLALPVYA
VVILGFTKKFEKLNDEQMESNAVLSSSVIEDIQGIETIKALNSEDTRYRRIDSQFVNYLKKSFKYSKAESLQTALKTFIQ
LSLNVIILWVGARVVMQGQMSIGQLMTFNALLSYFIDPLQNIINLQPRLQSASVAQNRLNEVYQVQSEFNADTSIQNSAA
LERMIEYKHVDYRYGYGTDVLKNINLKIKPDEKLAIVGMSGSGKSTMVKLLVDFFSPSKGEVTLNGHATSEVNKHTLRSY
VNYVPQTPYIFSGTVKKNLLLGCRPDISEEDVIKACQIAGIDQEIASLPLQFETKLDENAKILSGGQKQRLTIARALLSP
AKVFIFDEVTSGLDTITEKRVVDNLMKLKDKTIIFIAHRLAIAERADKVVVIDQGQIVEEGSHEELMEQHGFYYDLVKG
Nucleotide
Download Length: 2160 bp
>NTDB_id=811606 P8R55_RS03450 WP_339961485.1 718777..720936(+) (comA) [Lactobacillus johnsonii strain L16]
ATGTTATTCAAATATAAATCTGTTTATGTACCTCAAGTAGATGAGATGGATTGCGGAGTTGCTTGTCTAGCAATGATCTT
AAAGCAGTATCAATCTCGTGTGTCTTTAGCACATTTGCGTCGCGAAGCTCGCACAAATCTTGAAGGCACAACTGCGCTGG
GACTAGTTAAAACAGCACAGAAATTTAATTTTAAAACTGAAGCCGTAAAAGCTGATATGTCTCTTTTTAATGAGGATACT
ATTCAATACCCTTTTATCGTGCATGTTCTTAAGCAAGGAGAATTACTTCATTATTACGTAGTTCTTAAAAATACTAAGAA
TTACTTAGTAATTGCCGATCCTGATCCATCAGTTGGCATAATAAAGATGCCTAAAGATAAATTTGCTCAAGAATGGACTG
GTATTGCGCTTTTTATGGTTCCGAATGAAGATTTTGAACCAATTAAAGAAAAGAAAAATAACCTATGGTCTCTCTTTCCA
TATATGTTTAAGCAAAAGCGGCTGATGATTAATATCATTTTAGCCGCTTTATTAATGACAATAATTAGTATTTGTAGTTC
ATACTTTGTGCAAGGAATAATCGATACTTATATTCCCGATGGAACTTATCAGACTCTTTCAATTTTAGCTGTTGGACTAT
TAATTGCTTATATTTTTAATTCAATCTTTTCTTATGGACAGAATTTTTTATTAAATGTTCTAGGTCAAAGATTAAGTATT
GATTTAAACCTCCAATATATAAGGCATATTTTTGAATTGCCAATGGAATTCTTTGTGACTAGAAGAACTGGTGAAATAAC
CTCACGTTTCTCTGATGCAAGTAGAATTATTGATGCTCTAGCAAGTACTGTTATTTCACTTTTCTTAGACTTAGCGATTG
TAATTGTAATGGGACTAGTGTTAGCTGCTCAAAATATGACCTTATTTGGAATCACATTATTAGCTTTACCAGTATATGCT
GTAGTAATTCTGGGATTTACTAAGAAATTTGAAAAGTTAAATGATGAACAAATGGAGAGCAATGCAGTACTAAGTTCTTC
AGTCATCGAAGATATTCAAGGTATTGAAACTATCAAAGCTCTCAATAGTGAAGATACAAGATATCGTAGAATCGATAGCC
AATTTGTAAATTATTTAAAGAAGTCATTTAAATATAGTAAGGCTGAGAGTTTGCAGACGGCGTTAAAGACATTTATTCAA
CTATCTCTTAATGTAATTATTTTATGGGTTGGCGCACGAGTAGTGATGCAAGGACAGATGAGTATCGGTCAATTAATGAC
TTTTAATGCATTACTATCTTATTTCATTGACCCACTTCAAAATATTATTAACTTACAACCTCGTCTTCAATCAGCTAGTG
TTGCACAAAATAGATTGAACGAGGTTTATCAGGTGCAAAGTGAATTTAATGCAGATACTTCTATCCAGAACTCAGCTGCT
TTAGAAAGAATGATTGAATACAAGCATGTTGATTATCGATATGGTTATGGGACGGATGTTTTAAAAAACATTAATCTAAA
AATTAAGCCAGATGAAAAATTAGCAATTGTTGGCATGAGTGGATCAGGAAAATCGACAATGGTTAAGTTACTCGTTGATT
TCTTTTCACCAAGTAAGGGAGAAGTAACTTTAAATGGTCATGCAACTAGTGAAGTTAATAAACATACCTTACGCTCATAT
GTTAACTATGTTCCTCAAACGCCATATATCTTTTCTGGAACAGTTAAGAAGAATTTATTACTCGGCTGCAGACCGGATAT
TAGCGAAGAAGATGTAATTAAAGCCTGTCAGATTGCTGGAATTGATCAGGAGATAGCTAGTTTGCCACTACAATTCGAGA
CAAAGTTAGATGAGAATGCCAAGATTTTATCCGGTGGACAAAAGCAGAGATTAACTATTGCTAGAGCATTACTCTCGCCA
GCAAAAGTTTTTATCTTTGATGAAGTAACAAGTGGCTTAGATACAATTACAGAAAAAAGAGTAGTTGACAATCTTATGAA
ACTAAAAGACAAGACAATCATTTTTATTGCACACCGTCTAGCCATTGCGGAACGTGCGGATAAAGTAGTTGTAATTGATC
AGGGGCAAATTGTTGAAGAAGGAAGTCATGAAGAGCTTATGGAGCAACATGGTTTTTATTATGACTTAGTAAAGGGATAG
ATGTTATTCAAATATAAATCTGTTTATGTACCTCAAGTAGATGAGATGGATTGCGGAGTTGCTTGTCTAGCAATGATCTT
AAAGCAGTATCAATCTCGTGTGTCTTTAGCACATTTGCGTCGCGAAGCTCGCACAAATCTTGAAGGCACAACTGCGCTGG
GACTAGTTAAAACAGCACAGAAATTTAATTTTAAAACTGAAGCCGTAAAAGCTGATATGTCTCTTTTTAATGAGGATACT
ATTCAATACCCTTTTATCGTGCATGTTCTTAAGCAAGGAGAATTACTTCATTATTACGTAGTTCTTAAAAATACTAAGAA
TTACTTAGTAATTGCCGATCCTGATCCATCAGTTGGCATAATAAAGATGCCTAAAGATAAATTTGCTCAAGAATGGACTG
GTATTGCGCTTTTTATGGTTCCGAATGAAGATTTTGAACCAATTAAAGAAAAGAAAAATAACCTATGGTCTCTCTTTCCA
TATATGTTTAAGCAAAAGCGGCTGATGATTAATATCATTTTAGCCGCTTTATTAATGACAATAATTAGTATTTGTAGTTC
ATACTTTGTGCAAGGAATAATCGATACTTATATTCCCGATGGAACTTATCAGACTCTTTCAATTTTAGCTGTTGGACTAT
TAATTGCTTATATTTTTAATTCAATCTTTTCTTATGGACAGAATTTTTTATTAAATGTTCTAGGTCAAAGATTAAGTATT
GATTTAAACCTCCAATATATAAGGCATATTTTTGAATTGCCAATGGAATTCTTTGTGACTAGAAGAACTGGTGAAATAAC
CTCACGTTTCTCTGATGCAAGTAGAATTATTGATGCTCTAGCAAGTACTGTTATTTCACTTTTCTTAGACTTAGCGATTG
TAATTGTAATGGGACTAGTGTTAGCTGCTCAAAATATGACCTTATTTGGAATCACATTATTAGCTTTACCAGTATATGCT
GTAGTAATTCTGGGATTTACTAAGAAATTTGAAAAGTTAAATGATGAACAAATGGAGAGCAATGCAGTACTAAGTTCTTC
AGTCATCGAAGATATTCAAGGTATTGAAACTATCAAAGCTCTCAATAGTGAAGATACAAGATATCGTAGAATCGATAGCC
AATTTGTAAATTATTTAAAGAAGTCATTTAAATATAGTAAGGCTGAGAGTTTGCAGACGGCGTTAAAGACATTTATTCAA
CTATCTCTTAATGTAATTATTTTATGGGTTGGCGCACGAGTAGTGATGCAAGGACAGATGAGTATCGGTCAATTAATGAC
TTTTAATGCATTACTATCTTATTTCATTGACCCACTTCAAAATATTATTAACTTACAACCTCGTCTTCAATCAGCTAGTG
TTGCACAAAATAGATTGAACGAGGTTTATCAGGTGCAAAGTGAATTTAATGCAGATACTTCTATCCAGAACTCAGCTGCT
TTAGAAAGAATGATTGAATACAAGCATGTTGATTATCGATATGGTTATGGGACGGATGTTTTAAAAAACATTAATCTAAA
AATTAAGCCAGATGAAAAATTAGCAATTGTTGGCATGAGTGGATCAGGAAAATCGACAATGGTTAAGTTACTCGTTGATT
TCTTTTCACCAAGTAAGGGAGAAGTAACTTTAAATGGTCATGCAACTAGTGAAGTTAATAAACATACCTTACGCTCATAT
GTTAACTATGTTCCTCAAACGCCATATATCTTTTCTGGAACAGTTAAGAAGAATTTATTACTCGGCTGCAGACCGGATAT
TAGCGAAGAAGATGTAATTAAAGCCTGTCAGATTGCTGGAATTGATCAGGAGATAGCTAGTTTGCCACTACAATTCGAGA
CAAAGTTAGATGAGAATGCCAAGATTTTATCCGGTGGACAAAAGCAGAGATTAACTATTGCTAGAGCATTACTCTCGCCA
GCAAAAGTTTTTATCTTTGATGAAGTAACAAGTGGCTTAGATACAATTACAGAAAAAAGAGTAGTTGACAATCTTATGAA
ACTAAAAGACAAGACAATCATTTTTATTGCACACCGTCTAGCCATTGCGGAACGTGCGGATAAAGTAGTTGTAATTGATC
AGGGGCAAATTGTTGAAGAAGGAAGTCATGAAGAGCTTATGGAGCAACATGGTTTTTATTATGACTTAGTAAAGGGATAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comA | Streptococcus mitis NCTC 12261 |
56.742 |
99.026 |
0.562 |
| comA | Streptococcus mitis SK321 |
56.32 |
99.026 |
0.558 |
| comA | Streptococcus pneumoniae Rx1 |
56.18 |
99.026 |
0.556 |
| comA | Streptococcus pneumoniae D39 |
56.18 |
99.026 |
0.556 |
| comA | Streptococcus pneumoniae R6 |
56.18 |
99.026 |
0.556 |
| comA | Streptococcus pneumoniae TIGR4 |
56.039 |
99.026 |
0.555 |
| comA | Streptococcus gordonii str. Challis substr. CH1 |
55.056 |
99.026 |
0.545 |
| comA/nlmT | Streptococcus mutans UA159 |
53.182 |
98.331 |
0.523 |