Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/comE1   Type   Regulator
Locus tag   P7Y79_RS00955 Genome accession   NZ_CP121207
Coordinates   206315..207046 (+) Length   243 a.a.
NCBI ID   WP_166043387.1    Uniprot ID   -
Organism   Streptococcus ruminicola strain CNU_77-47     
Function   activate transcription of early competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 201315..212046
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P7Y79_RS00935 (P7Y79_00935) comA/nlmT 201733..203880 (-) 2148 WP_278007562.1 peptide cleavage/export ABC transporter Regulator
  P7Y79_RS00940 (P7Y79_00940) - 204119..204346 (+) 228 WP_278007563.1 ComC/BlpC family peptide pheromone/bacteriocin -
  P7Y79_RS00945 (P7Y79_00945) - 204412..204723 (+) 312 WP_061408660.1 hypothetical protein -
  P7Y79_RS00950 (P7Y79_00950) - 204913..205527 (+) 615 WP_278007564.1 thioredoxin fold domain-containing protein -
  P7Y79_RS00955 (P7Y79_00955) comE/comE1 206315..207046 (+) 732 WP_166043387.1 response regulator transcription factor Regulator
  P7Y79_RS00960 (P7Y79_00960) - 207052..208377 (+) 1326 WP_157327340.1 GHKL domain-containing protein -
  P7Y79_RS00965 (P7Y79_00965) comC/comC1 208400..208552 (-) 153 WP_157327338.1 hypothetical protein Regulator
  P7Y79_RS00970 (P7Y79_00970) - 208814..208963 (+) 150 WP_278007565.1 bacteriocin -
  P7Y79_RS00975 (P7Y79_00975) - 208976..209281 (+) 306 WP_158914537.1 bacteriocin immunity protein -
  P7Y79_RS00980 (P7Y79_00980) - 209309..209431 (+) 123 WP_278007566.1 hypothetical protein -
  P7Y79_RS00985 (P7Y79_00985) comD/comD2 210393..211340 (+) 948 WP_278007567.1 GHKL domain-containing protein Regulator

Sequence

Protein


Download         Length: 243 a.a.        Molecular weight: 28194.11 Da        Isoelectric Point: 6.0479

>NTDB_id=811076 P7Y79_RS00955 WP_166043387.1 206315..207046(+) (comE/comE1) [Streptococcus ruminicola strain CNU_77-47]
MLDIFILEDNITQQFRIERQIETIMERNHWEYQRLEAFAASKDIIKKADGQGNYQVFFLDLEIKGDEKQGLDVARSIREK
DPTAIIVFVTTHSEFMLLTYQSLVGAIDFIDKNMNDEAFGGRIELCLKEALKYQTGSFGENSYLFETAKARIRVAYDDIL
YFETSPTVHRVILHTKTGQTEFYGTIAEVAKSDKRLLKCHRSFVINVNNVTEFDKSTRTAYFENGSYCQVSRDKVKKLMA
EMR

Nucleotide


Download         Length: 732 bp        

>NTDB_id=811076 P7Y79_RS00955 WP_166043387.1 206315..207046(+) (comE/comE1) [Streptococcus ruminicola strain CNU_77-47]
ATGTTAGATATTTTTATCCTTGAGGATAATATTACGCAACAATTTCGAATTGAACGTCAGATTGAGACGATTATGGAAAG
GAACCACTGGGAGTATCAGCGTTTAGAGGCTTTTGCGGCATCTAAGGATATTATAAAAAAGGCAGATGGGCAGGGAAATT
ACCAGGTTTTCTTTCTTGATTTAGAAATCAAAGGGGATGAAAAGCAAGGCTTAGATGTTGCTAGATCTATTCGTGAAAAA
GATCCGACAGCCATTATCGTCTTTGTGACAACCCATTCTGAGTTTATGCTTCTAACTTATCAATCACTAGTTGGTGCGAT
TGATTTTATTGATAAAAATATGAATGATGAAGCCTTTGGAGGGCGCATTGAATTGTGCTTGAAAGAGGCATTGAAATATC
AAACTGGTAGTTTTGGCGAGAATTCTTACCTGTTTGAAACAGCAAAAGCAAGAATCCGTGTGGCTTATGATGATATTTTA
TATTTTGAAACATCGCCAACCGTGCACCGTGTGATTTTACACACTAAAACAGGTCAAACAGAGTTTTATGGCACAATCGC
TGAGGTAGCCAAATCAGATAAACGTTTGTTGAAATGTCACCGCTCATTCGTGATTAATGTTAATAATGTCACTGAATTTG
ATAAAAGTACCCGAACAGCTTATTTCGAAAACGGCTCTTACTGCCAAGTCTCAAGAGACAAAGTCAAAAAACTGATGGCA
GAAATGAGGTGA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(152-240)

Response regulator receiver domain (Response_reg)

(4-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/comE1 Streptococcus equinus JB1

99.588

100

0.996
  comE/blpR Streptococcus mutans UA159

46.473

99.177

0.461
  comE/comE2 Streptococcus equinus JB1

45.041

99.588

0.449