Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   P7F70_RS08025 Genome accession   NZ_CP121201
Coordinates   1591843..1593726 (-) Length   627 a.a.
NCBI ID   WP_278023986.1    Uniprot ID   -
Organism   Streptococcus pluranimalium strain SP28     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1586843..1598726
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P7F70_RS08000 (P7F70_08005) - 1587547..1587906 (-) 360 WP_104968357.1 S1 RNA-binding domain-containing protein -
  P7F70_RS08005 (P7F70_08010) - 1587906..1589306 (-) 1401 WP_278023984.1 Cof-type HAD-IIB family hydrolase -
  P7F70_RS08010 (P7F70_08015) - 1589354..1589992 (-) 639 WP_104968359.1 response regulator transcription factor -
  P7F70_RS08015 (P7F70_08020) - 1589985..1590983 (-) 999 WP_278023985.1 sensor histidine kinase -
  P7F70_RS08020 (P7F70_08025) liaF 1590980..1591678 (-) 699 WP_104968361.1 cell wall-active antibiotics response protein LiaF -
  P7F70_RS08025 (P7F70_08030) stkP/pknB 1591843..1593726 (-) 1884 WP_278023986.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  P7F70_RS08030 (P7F70_08035) - 1593726..1594463 (-) 738 WP_115131188.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  P7F70_RS08035 (P7F70_08040) rsmB 1594512..1595834 (-) 1323 WP_278023987.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  P7F70_RS08040 (P7F70_08045) fmt 1595824..1596765 (-) 942 WP_278023988.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 627 a.a.        Molecular weight: 68266.49 Da        Isoelectric Point: 4.8099

>NTDB_id=811012 P7F70_RS08025 WP_278023986.1 1591843..1593726(-) (stkP/pknB) [Streptococcus pluranimalium strain SP28]
MIQIGKLFAGRYRILKSIGRGGMADVYLAHDLILDNEEVAIKVLRTNYQTDQIAVARFQREARAMAELNHPNIVAIRDIG
EEDGQQFLAMEYVNGPDLKKYIQDHAPLSNTETVRIMSEVLSAMQLAHQKGIVHRDLKPQNVLLTKDGVAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTCHIPFDGDSAVTIALQHFQKPLPSIIFENRNVP
QALENVVIKATAKKLGDRYVSTTDMYQDLGTSLDSRRARESKLVFQDTTDTKTLPKIEPSPVKEAPKAAVAPESVEMPKE
KEASKKEVSTPPSSKKSKKSFWQRLFRFFILALVLLLAGFAFFFMSSSNDSATVPDVSGQTIQEAQATLEEAGLTVGAVS
RKESDSVEEGKVISTTPKSGTTQKEGSEVNLLVSKGSKRFVMTDYTGMSYRDAVSDLIENYGLSKNQIVKKEVTNNQYEP
GEIVSQTPEAGEDFNPSGNDKIIFEVATSSTVTIPTLVGYSYADAKNALLDLGFKASQIQTDSDQPSSSATVYAQYPYAG
TSVELSSGETVTLYLTTPEPSSTQPSSSSEEIDTDSSNQTSSSSSSSSSNHSTEATGDANSQPETTD

Nucleotide


Download         Length: 1884 bp        

>NTDB_id=811012 P7F70_RS08025 WP_278023986.1 1591843..1593726(-) (stkP/pknB) [Streptococcus pluranimalium strain SP28]
ATGATCCAAATCGGCAAATTATTTGCTGGGCGTTATCGTATTTTAAAATCTATCGGTCGCGGTGGTATGGCTGATGTTTA
TTTGGCACATGATTTGATTTTGGATAATGAAGAAGTAGCGATTAAGGTGCTTCGAACCAATTATCAAACAGATCAAATTG
CAGTCGCACGTTTCCAGAGAGAAGCGCGTGCGATGGCTGAATTAAATCATCCTAACATTGTAGCTATCAGAGATATCGGC
GAAGAAGATGGACAACAATTTCTTGCCATGGAATACGTTAATGGTCCAGATTTAAAGAAGTATATTCAAGATCATGCACC
TCTTTCTAATACTGAGACAGTTCGTATCATGAGTGAGGTGTTATCAGCTATGCAGCTGGCTCATCAAAAAGGAATTGTTC
ATCGTGACTTGAAACCACAGAATGTTCTTTTGACAAAAGACGGAGTAGCTAAGGTAACTGATTTTGGGATTGCTGTAGCC
TTTGCAGAGACAAGTTTGACACAGACAAATTCGATGTTAGGAAGTGTTCATTACTTGTCACCAGAGCAAGCACGAGGCTC
TAAAGCAACGATACAAAGTGATATTTATGCTATGGGTATCATGTTGTTTGAAATGTTGACTTGTCATATCCCATTTGATG
GTGATAGTGCTGTTACGATTGCATTGCAACACTTTCAGAAACCTTTGCCATCGATTATTTTTGAAAATCGAAATGTTCCA
CAAGCTTTGGAGAATGTTGTTATCAAAGCAACTGCTAAAAAGCTCGGAGATCGCTATGTATCAACGACCGATATGTATCA
AGATTTAGGGACATCCCTAGATTCGCGCCGTGCTAGAGAATCAAAGTTAGTTTTTCAAGATACAACAGATACTAAGACAT
TACCTAAAATTGAGCCTTCACCTGTTAAAGAGGCACCTAAAGCAGCAGTTGCTCCGGAAAGTGTCGAAATGCCTAAAGAA
AAGGAAGCTTCTAAAAAAGAAGTCTCTACACCGCCGTCATCTAAAAAGTCTAAGAAATCTTTTTGGCAACGTCTATTCAG
ATTTTTCATTTTGGCCCTCGTTTTATTACTAGCCGGTTTTGCATTCTTCTTTATGTCAAGTAGTAATGATAGTGCAACAG
TTCCTGATGTCTCAGGGCAAACAATCCAAGAAGCTCAAGCCACTCTAGAAGAGGCTGGTTTGACTGTAGGAGCTGTTTCT
CGTAAAGAAAGTGATAGTGTTGAGGAAGGAAAGGTCATTTCAACAACACCGAAATCAGGAACCACTCAAAAAGAGGGAAG
CGAAGTTAATTTACTAGTTTCAAAAGGTTCTAAACGCTTTGTTATGACAGATTATACCGGGATGTCATATAGGGATGCTG
TTAGTGATTTGATAGAAAATTATGGTTTGTCTAAAAATCAAATTGTCAAAAAAGAAGTTACAAATAATCAGTATGAACCG
GGAGAAATTGTTAGTCAGACTCCAGAAGCTGGCGAAGATTTTAACCCTTCAGGTAATGATAAGATTATTTTTGAAGTAGC
AACATCTTCTACAGTAACAATACCAACCTTGGTTGGTTACAGTTATGCAGATGCCAAGAATGCTTTATTAGACCTAGGAT
TTAAAGCTTCTCAGATTCAGACAGATTCAGATCAACCGTCGTCATCGGCAACGGTCTATGCACAATACCCATATGCAGGG
ACGTCTGTTGAACTCTCATCTGGAGAAACGGTAACATTGTATCTAACAACTCCTGAGCCATCATCGACGCAACCGTCATC
ATCTTCTGAGGAGATAGATACGGATAGCAGTAATCAGACCTCTTCATCAAGTAGTTCTTCTAGTTCCAACCATTCAACGG
AAGCAACAGGTGATGCAAACAGCCAACCAGAAACTACTGATTAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-227)

PASTA domain (PASTA)

(373-435)

PASTA domain (PASTA)

(512-576)

PASTA domain (PASTA)

(441-507)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

62.799

93.461

0.587
  pknB Streptococcus mutans UA159

60.678

94.099

0.571
  stkP Streptococcus pneumoniae TIGR4

53.638

94.258

0.506
  stkP Streptococcus pneumoniae D39

53.469

94.258

0.504
  stkP Streptococcus pneumoniae R6

53.469

94.258

0.504
  stkP Streptococcus pneumoniae Rx1

53.299

94.258

0.502