Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   P7F70_RS01430 Genome accession   NZ_CP121201
Coordinates   266396..267154 (+) Length   252 a.a.
NCBI ID   WP_278024921.1    Uniprot ID   -
Organism   Streptococcus pluranimalium strain SP28     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 261396..272154
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P7F70_RS01405 (P7F70_01405) - 262665..263168 (-) 504 WP_104967214.1 phosphatidylglycerophosphatase A -
  P7F70_RS01410 (P7F70_01410) - 263375..264691 (+) 1317 WP_278024918.1 FAD-containing oxidoreductase -
  P7F70_RS01415 (P7F70_01415) - 264701..265057 (+) 357 WP_278024919.1 DUF2200 domain-containing protein -
  P7F70_RS01420 (P7F70_01420) - 265262..265819 (+) 558 WP_278024920.1 DUF1697 domain-containing protein -
  P7F70_RS01425 (P7F70_01425) - 265820..266317 (+) 498 WP_340654446.1 phosphatase PAP2 family protein -
  P7F70_RS01430 (P7F70_01430) mecA 266396..267154 (+) 759 WP_278024921.1 adaptor protein MecA Regulator
  P7F70_RS01435 (P7F70_01435) - 267155..268312 (+) 1158 WP_278024922.1 MraY family glycosyltransferase -
  P7F70_RS01440 (P7F70_01440) sufC 268420..269190 (+) 771 WP_104967221.1 Fe-S cluster assembly ATPase SufC -
  P7F70_RS01445 (P7F70_01445) - 269203..269718 (+) 516 WP_278024923.1 GNAT family N-acetyltransferase -
  P7F70_RS01450 (P7F70_01450) sufD 269722..270984 (+) 1263 WP_278024924.1 Fe-S cluster assembly protein SufD -

Sequence

Protein


Download         Length: 252 a.a.        Molecular weight: 28895.48 Da        Isoelectric Point: 4.1858

>NTDB_id=810978 P7F70_RS01430 WP_278024921.1 266396..267154(+) (mecA) [Streptococcus pluranimalium strain SP28]
MEMKQISETTLKITISMEDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKNSGMLSFRVTPKKDRLDVFVTKSEI
DKDLNFDDLAALGDVSQMSPDEFFKTLEKSMLEKGDTEAHEKLKQMEEIVESAMTEQTSEADLADESTEDNAEQDNYTHY
VLQFPMLKDAVAFSKAIDFDIEASELYKFNGSYYITILVSLENKPAYYADLVHARLLEHSRGGQKTRAYLQEHGVRLLEG
YAVADLEGIKVV

Nucleotide


Download         Length: 759 bp        

>NTDB_id=810978 P7F70_RS01430 WP_278024921.1 266396..267154(+) (mecA) [Streptococcus pluranimalium strain SP28]
ATGGAAATGAAACAAATTAGCGAAACAACGCTAAAAATCACGATTAGTATGGAAGATTTGGAAGAAAGAGGGATGGAATT
AAAAGATTTCCTTATTCCTCAAGAAAAAACGGAAGAATTTTTTTATTCCGTGATGGACGAACTTGATTTACCAGATAACT
TCAAAAATAGTGGCATGTTGAGTTTTCGAGTGACACCTAAGAAAGATCGATTAGATGTTTTTGTAACTAAGTCTGAAATT
GATAAGGATTTAAACTTTGATGATTTAGCAGCCTTGGGGGATGTCTCTCAAATGTCTCCGGATGAATTCTTTAAGACATT
AGAAAAATCAATGTTGGAGAAGGGAGACACTGAAGCTCACGAGAAGTTAAAACAAATGGAAGAAATCGTGGAATCTGCGA
TGACAGAGCAAACATCAGAAGCAGACTTAGCAGATGAATCGACTGAAGATAATGCTGAACAAGACAATTATACGCACTAT
GTGTTACAGTTTCCCATGCTGAAAGATGCCGTTGCTTTTTCAAAAGCGATTGACTTTGATATAGAAGCATCAGAACTGTA
TAAATTCAATGGCAGTTACTATATTACTATCTTGGTCAGTCTAGAAAATAAGCCCGCTTATTATGCCGACTTGGTTCACG
CTCGCTTGTTGGAGCACAGTCGTGGTGGTCAAAAAACAAGAGCCTATCTGCAAGAGCATGGCGTCCGTTTGCTTGAAGGC
TATGCAGTGGCTGATTTAGAAGGTATCAAGGTGGTCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

59.839

98.81

0.591
  mecA Streptococcus thermophilus LMD-9

55.512

100

0.56
  mecA Streptococcus thermophilus LMG 18311

54.724

100

0.552
  mecA Streptococcus pneumoniae Rx1

49.603

100

0.496
  mecA Streptococcus pneumoniae D39

49.603

100

0.496
  mecA Streptococcus pneumoniae R6

49.603

100

0.496
  mecA Streptococcus pneumoniae TIGR4

49.603

100

0.496