Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   RS173_RS16280 Genome accession   NZ_CP135643
Coordinates   3390443..3392464 (-) Length   673 a.a.
NCBI ID   WP_000042537.1    Uniprot ID   -
Organism   Escherichia coli strain TUM17543     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 3385443..3397464
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RS173_RS16245 (RS173_16245) ybhL 3385556..3386260 (-) 705 WP_000373624.1 Bax inhibitor-1/YccA family protein -
  RS173_RS16250 (RS173_16250) moaE 3386397..3386849 (-) 453 WP_000852287.1 molybdopterin synthase catalytic subunit MoaE -
  RS173_RS16255 (RS173_16255) moaD 3386851..3387096 (-) 246 WP_000611261.1 molybdopterin synthase sulfur carrier subunit -
  RS173_RS16260 (RS173_16260) moaC 3387089..3387574 (-) 486 WP_000080885.1 cyclic pyranopterin monophosphate synthase MoaC -
  RS173_RS16265 (RS173_16265) moaB 3387577..3388089 (-) 513 WP_000084640.1 molybdenum cofactor biosynthesis protein B -
  RS173_RS16270 (RS173_16270) moaA 3388111..3389100 (-) 990 WP_001295301.1 GTP 3',8-cyclase MoaA -
  RS173_RS16275 (RS173_16275) yvcK 3389497..3390405 (+) 909 WP_001304790.1 uridine diphosphate-N-acetylglucosamine-binding protein YvcK -
  RS173_RS16280 (RS173_16280) uvrB 3390443..3392464 (-) 2022 WP_000042537.1 excinuclease ABC subunit UvrB Machinery gene
  RS173_RS16285 (RS173_16285) bioD 3393043..3393720 (-) 678 WP_000030923.1 dethiobiotin synthase -
  RS173_RS16290 (RS173_16290) bioC 3393713..3394468 (-) 756 WP_000246763.1 malonyl-ACP O-methyltransferase BioC -
  RS173_RS16295 (RS173_16295) bioF 3394455..3395609 (-) 1155 WP_000638120.1 8-amino-7-oxononanoate synthase -
  RS173_RS16300 (RS173_16300) bioB 3395606..3396646 (-) 1041 WP_000951218.1 biotin synthase BioB -

Sequence

Protein


Download         Length: 673 a.a.        Molecular weight: 76240.08 Da        Isoelectric Point: 4.8860

>NTDB_id=810889 RS173_RS16280 WP_000042537.1 3390443..3392464(-) (uvrB) [Escherichia coli strain TUM17543]
MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEF
FPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLH
LTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFDEEVERLSLFDPLTGQIVSTIPR
FTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLENNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGE
PPPTLFDYLPADGLLVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYVSATPGNYE
LEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDELLSEIRQRAAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDI
DTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPS
MAKAIGETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVPMDMSPKALQQKIHELE
GLMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS

Nucleotide


Download         Length: 2022 bp        

>NTDB_id=810889 RS173_RS16280 WP_000042537.1 3390443..3392464(-) (uvrB) [Escherichia coli strain TUM17543]
ATGAGTAAACCGTTCAAACTGAATTCCGCTTTTAAACCTTCTGGCGATCAGCCGGAGGCGATTCGACGTCTCGAAGAGGG
GCTGGAAGATGGCCTGGCGCACCAGACGTTACTTGGCGTGACTGGCTCCGGGAAAACCTTCACCATTGCCAATGTCATTG
CTGACCTTCAGCGCCCAACCATGGTACTTGCGCCCAACAAAACGCTGGCGGCCCAGCTGTATGGCGAAATGAAAGAATTC
TTTCCGGAAAACGCGGTGGAATATTTCGTCTCCTACTACGACTACTATCAGCCGGAGGCCTATGTACCGAGTTCCGACAC
CTTCATTGAGAAAGATGCCTCGGTAAACGAACATATCGAACAGATGCGTTTGTCCGCCACCAAAGCGATGCTGGAGCGGC
GTGATGTGGTTGTGGTGGCGTCTGTTTCCGCGATTTATGGTCTGGGCGATCCTGATTTATATCTCAAGATGATGCTCCAT
CTCACGGTCGGTATGATTATCGATCAGCGCGCGATCCTGCGCCGACTGGCGGAGCTGCAATATGCTCGTAATGATCAAGC
ATTCCAGCGTGGTACTTTCCGTGTTCGTGGCGAGGTGATTGATATCTTCCCGGCAGAATCGGATGACATTGCACTTCGCG
TGGAGCTGTTTGACGAGGAGGTGGAACGATTGTCGTTATTTGACCCGCTGACCGGGCAGATTGTTTCCACTATTCCACGT
TTTACCATCTACCCGAAAACGCACTACGTCACGCCACGCGAGCGCATCGTCCAGGCGATGGAGGAGATCAAAGAAGAGCT
GGCCGCCAGACGTAAAGTGCTATTGGAAAACAACAAACTGCTGGAAGAGCAGCGGCTGACCCAGCGTACCCAGTTTGATC
TGGAGATGATGAACGAGCTAGGCTACTGTTCGGGGATTGAGAACTACTCGCGCTTCCTCTCCGGTCGTGGACCGGGTGAG
CCACCGCCGACGCTGTTTGATTACCTGCCTGCTGATGGGCTGCTGGTGGTCGATGAATCTCACGTCACCATTCCACAAAT
TGGCGGCATGTATCGCGGTGACCGGGCGCGTAAAGAGACACTGGTGGAGTACGGCTTCCGCCTGCCATCAGCGCTGGATA
ACCGTCCGCTGAAATTTGAAGAGTTCGAAGCATTAGCGCCGCAAACCATCTATGTTTCGGCGACGCCGGGTAATTACGAG
CTGGAAAAATCCGGTGGCGATGTGGTGGATCAGGTGGTGCGTCCAACAGGCTTACTCGACCCGATTATCGAAGTGCGGCC
AGTGGCAACACAGGTGGATGAGCTTCTTTCGGAGATTCGTCAGCGAGCGGCAATTAACGAACGCGTACTGGTTACAACTC
TGACCAAGCGGATGGCGGAAGATCTCACTGAATATCTCGAAGAACACGGTGAGCGCGTGCGTTATCTTCACTCAGATATC
GACACCGTCGAACGTATGGAGATTATCCGCGACTTGCGTCTGGGTGAGTTCGACGTATTGGTAGGGATCAACTTACTGCG
CGAAGGTCTGGATATGCCGGAAGTTTCGCTGGTGGCGATCCTCGACGCTGACAAAGAAGGCTTCCTGCGTTCCGAACGTT
CGTTGATCCAGACCATTGGTCGTGCGGCACGTAACGTTAACGGTAAAGCGATTCTCTACGGCGATAAGATCACCCCATCA
ATGGCGAAAGCGATTGGCGAAACCGAACGTCGCCGCGAGAAACAGCAGAAGTACAACGAAGAACACGGCATTACGCCGCA
AGGCTTGAACAAGAAAGTGGTCGATATCCTGGCGCTGGGGCAGAACATTGCCAAAACCAAAGCGAAGGGCAGAGGAAAAT
CGCGCCCGATTGTTGAACCGGATAATGTGCCGATGGATATGTCGCCTAAAGCGTTACAGCAGAAGATCCATGAACTGGAA
GGGTTGATGATGCAACACGCGCAGAATCTGGAGTTCGAAGAAGCGGCGCAAATTCGTGACCAGTTGCATCAGTTGCGTGA
GCTGTTTATTGCCGCGTCGTGA

Domains

Predicted by InterProScan.

Helicase conserved C-terminal domain (Helicase_C)

(436-544)

UvrB interaction domain (UvrB_inter)

(159-249)

UvrB/uvrC motif (UVR)

(634-667)

Ultra-violet resistance protein B (UvrB)

(552-593)

Type III restriction enzyme, res subunit (ResIII)

(13-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

56.222

99.108

0.557
  uvrB Streptococcus pneumoniae R6

56.072

99.108

0.556
  uvrB Streptococcus pneumoniae D39

56.072

99.108

0.556