Detailed information NTG0809336

Bioinformatically predicted

Overview

• Name: comFA
• Type: Machinery gene
• Locus tag: LLHP_RS06460
• Genome accession: NZ_CP120921
• Coordinates: 1289819..1290604 (+)
• Length: 261 a.a.
• NCBI ID: WP_021214114.1
• Uniprot ID: -
• Organism: Lactococcus cremoris subsp. cremoris HP
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1284819..1295604

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLHP_RS06435 (LLHP_06465)	-	1285740..1286387 (-)	648	WP_011676100.1	GIY-YIG nuclease family protein	-
LLHP_RS06440 (LLHP_06470)	-	1286624..1287391 (-)	768	WP_011676099.1	5'-nucleotidase	-
LLHP_RS06445 (LLHP_06475)	-	1287500..1288519 (-)	1020	WP_032951092.1	DUF475 domain-containing protein	-
LLHP_RS06450 (LLHP_06480)	-	1288585..1289085 (-)	501	WP_032951093.1	VanZ family protein	-
LLHP_RS06455 (LLHP_06485)	-	1289127..1289762 (-)	636	WP_011676097.1	YigZ family protein	-
LLHP_RS06460 (LLHP_06490)	comFA	1289819..1290604 (+)	786	WP_021214114.1	DEAD/DEAH box helicase family protein	Machinery gene
LLHP_RS06465 (LLHP_06495)	-	1290702..1291637 (-)	936	WP_031559015.1	IS30 family transposase	-
LLHP_RS06470 (LLHP_06500)	comFA	1291773..1292189 (+)	417	WP_257589739.1	helicase-related protein	Machinery gene
LLHP_RS06475 (LLHP_06505)	comFC	1292189..1292839 (+)	651	WP_032951095.1	ComF family protein	Machinery gene
LLHP_RS06480 (LLHP_06510)	-	1292897..1293475 (-)	579	WP_011676095.1	nucleotidyltransferase family protein	-
LLHP_RS06485 (LLHP_06515)	-	1293492..1293947 (-)	456	WP_011676094.1	diacylglycerol kinase family protein	-
LLHP_RS06490 (LLHP_06520)	ybeY	1293931..1294419 (-)	489	WP_032951096.1	rRNA maturation RNase YbeY	-
LLHP_RS06495 (LLHP_06525)	-	1294510..1295004 (-)	495	WP_011676092.1	NUDIX hydrolase	-

Sequence

Protein

• Length: 261 a.a.
• Molecular weight: 29919.55 Da
• Isoelectric Point: 7.8588

>NTDB_id=809336 LLHP_RS06460 WP_021214114.1 1289819..1290604(+) (comFA) [Lactococcus cremoris subsp. cremoris HP]
MNLILENLLGRLLLEKDISAFYNFTDQVNNENKLIKICAMTSVNANKVRCNRCGTIHIKTNVKLPIGAFFCPTCLELGRV
RSDEYFYHLPQQDFSEKTYLRWTGKLTENQEKISNALCQQITNNQKRLVQAVTGAGKTEMIYQLIEQILSHGGSVGLASP
RIDVCIELHQRLSRDFTCQIPLLYHEGDSYFRSPLVVMTSHQLLRFKEAFDLLIIDEVDAFPFRDNDMLYFALENAKKIN
GNLLYLTATSTDKLDKQIKKA

Nucleotide

• Length: 786 bp

>NTDB_id=809336 LLHP_RS06460 WP_021214114.1 1289819..1290604(+) (comFA) [Lactococcus cremoris subsp. cremoris HP]
ATGAACTTAATTTTAGAAAATCTCCTTGGGCGTCTTTTACTAGAAAAAGATATTTCAGCTTTTTATAATTTTACTGACCA
AGTTAACAATGAAAACAAATTAATTAAAATTTGTGCAATGACATCTGTCAATGCTAATAAAGTAAGATGTAATCGATGTG
GCACGATTCATATAAAAACCAATGTTAAACTTCCGATTGGTGCTTTTTTCTGTCCAACATGTCTTGAACTTGGTCGTGTC
CGCTCAGATGAATATTTCTATCATCTCCCTCAACAAGACTTTTCAGAAAAAACTTATTTACGTTGGACAGGAAAATTAAC
AGAAAATCAAGAAAAAATTTCTAACGCTCTCTGTCAGCAAATTACTAATAATCAAAAACGACTTGTTCAAGCCGTTACTG
GTGCTGGTAAAACAGAAATGATATATCAGCTTATTGAACAAATTCTTAGCCATGGGGGTTCGGTCGGTTTAGCCAGCCCA
AGAATTGATGTATGCATTGAGCTTCATCAACGTTTATCACGTGATTTCACTTGTCAAATTCCCCTTTTGTATCATGAGGG
AGATTCTTATTTTCGTTCGCCTTTGGTCGTTATGACCAGTCACCAACTTTTACGTTTCAAAGAGGCCTTTGATTTGCTTA
TCATCGATGAAGTCGATGCCTTTCCTTTTAGAGATAATGACATGCTTTATTTCGCTCTTGAAAATGCTAAAAAAATTAAT
GGAAACTTGCTCTACTTAACCGCTACATCTACTGACAAATTAGACAAACAGATAAAAAAAGCATGA

Domains

Predicted by InterproScan.

• Type III restriction enzyme, res subunit (ResIII) (105-249)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comFA	Lactococcus lactis subsp. cremoris KW2	97.308	99.617	0.969
comFA/cflA	Streptococcus mitis SK321	49.802	96.935	0.483
comFA/cflA	Streptococcus pneumoniae D39	49.012	96.935	0.475
comFA/cflA	Streptococcus pneumoniae Rx1	49.012	96.935	0.475
comFA/cflA	Streptococcus pneumoniae R6	49.012	96.935	0.475
comFA/cflA	Streptococcus pneumoniae TIGR4	49.012	96.935	0.475
comFA/cflA	Streptococcus mitis NCTC 12261	48.617	96.935	0.471
comFA	Bacillus subtilis subsp. subtilis str. 168	37.453	100	0.383