Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   P4831_RS00430 Genome accession   NZ_CP120842
Coordinates   77071..79218 (+) Length   715 a.a.
NCBI ID   WP_023163570.1    Uniprot ID   A0AAQ0U095
Organism   Lactococcus lactis strain ZFM559     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 72071..84218
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P4831_RS00405 - 73208..73675 (+) 468 WP_010905090.1 universal stress protein -
  P4831_RS00410 - 73804..74001 (+) 198 WP_010905091.1 DUF4649 domain-containing protein -
  P4831_RS00415 - 74032..74652 (+) 621 WP_023163569.1 alpha/beta hydrolase -
  P4831_RS00420 - 74703..75872 (+) 1170 WP_010905093.1 ring-cleaving dioxygenase -
  P4831_RS00425 - 75883..76473 (+) 591 WP_003132255.1 flavin reductase family protein -
  P4831_RS00430 comA 77071..79218 (+) 2148 WP_023163570.1 peptide cleavage/export ABC transporter Regulator
  P4831_RS00435 - 79233..80471 (+) 1239 WP_235585399.1 bacteriocin secretion accessory protein -
  P4831_RS00440 - 80748..80885 (+) 138 WP_021214958.1 lactococcin family bacteriocin -
  P4831_RS00445 - 80900..81610 (+) 711 WP_023163572.1 CPBP family intramembrane glutamic endopeptidase -
  P4831_RS00450 - 82036..82488 (+) 453 WP_010905102.1 transporter -
  P4831_RS00455 - 82699..83361 (-) 663 WP_021214959.1 type II CAAX endopeptidase family protein -
  P4831_RS00460 - 83670..83849 (-) 180 WP_023163573.1 hypothetical protein -
  P4831_RS00465 - 83870..84049 (-) 180 WP_023163574.1 lactococcin family bacteriocin -

Sequence

Protein


Download         Length: 715 a.a.        Molecular weight: 79879.46 Da        Isoelectric Point: 8.6006

>NTDB_id=808758 P4831_RS00430 WP_023163570.1 77071..79218(+) (comA) [Lactococcus lactis strain ZFM559]
MKFKKKNYTSQVDEMDCGCAALSMILKSYGTEKSLASLRLLAGTTIEGTSALGIKKAGEGLGFVVQVLRADASLFEMKKV
PYPFIAHVIKNQKYPHYYVITGANKNSVFIADPDPTVKMTKLSKEVFLSEWTGISLFLSPTPSYQPTKEKTSSLLSFIPI
ITRQKKVILNIVIASFIVTLINILGSYYLQSMIDSYIPNALMGTLGIISVGLLLTYIIQQVLEFAKAFLLNVLSQRLAID
VILSYIRHIFQLPMSFFSTRRTGEITSRFSDASSILDAIASTILSLFLDLTIVLMTGLILGLQNMQLFLLVLLAIPLYIV
VIIIFTPLFERQNHEVMQTNAILNSSIIEDINGIETIKALASEQERYQKIDYEFASYLKEAFTLQQSEAIQTAIKTTVQL
VLNVLILWFGATLVMHQKITLGQLITFNALLSYFTNPITNIINLQTKLQKARVANERLNEVYLIPSEFEEKKTELSLSHF
NLNMSEISYQYGFGRKVLSEIKLSIKENEKLTIVGISGSGKSTLVKLLVNFFQPTSGTITLGGIDLQQFDKHQLRRLINY
LPQQPYIFTGSIMDNLLLGASEATSQEEIIRAVELAEIRADIEQMQLGYQTELSSDASSLSGGQKQRIALARALLSPAKI
LILDEATSNLDMITEKKILKNLLALDKTIIFIAHRLSVAEMSHRIIVIEQGKVIESGSHSELLAQNGFYAQLYHN

Nucleotide


Download         Length: 2148 bp        

>NTDB_id=808758 P4831_RS00430 WP_023163570.1 77071..79218(+) (comA) [Lactococcus lactis strain ZFM559]
ATGAAATTTAAAAAGAAAAATTATACCTCCCAAGTAGATGAAATGGATTGTGGATGTGCTGCTTTATCAATGATTTTAAA
ATCCTATGGGACAGAAAAATCGCTTGCCTCTCTTCGTTTACTTGCTGGTACAACAATCGAGGGAACTTCCGCTTTAGGAA
TAAAAAAAGCAGGAGAAGGTTTAGGTTTTGTAGTTCAAGTACTAAGAGCTGATGCAAGCCTTTTTGAAATGAAGAAAGTC
CCTTACCCTTTTATTGCTCATGTCATCAAGAACCAAAAGTATCCACACTACTATGTGATAACTGGCGCAAATAAAAATTC
GGTATTCATCGCAGATCCTGACCCAACCGTTAAAATGACAAAACTTTCAAAAGAAGTTTTCTTATCAGAGTGGACAGGCA
TTAGCTTATTTCTTTCACCTACCCCATCCTATCAGCCCACTAAAGAAAAAACTTCTTCATTATTATCTTTTATCCCAATT
ATCACCCGTCAAAAGAAAGTCATTCTCAATATTGTAATTGCCTCATTCATTGTAACGTTGATTAATATTCTAGGGTCTTA
CTACCTCCAGAGCATGATTGATAGTTACATTCCAAATGCCTTAATGGGAACTTTAGGGATTATCTCAGTAGGGCTATTGT
TAACTTATATTATCCAACAAGTCTTAGAGTTTGCTAAGGCTTTCTTACTAAACGTTCTTTCTCAAAGATTAGCCATTGAT
GTCATCCTTTCCTATATTAGACACATTTTCCAACTCCCGATGTCTTTCTTTTCGACTAGAAGAACAGGGGAAATTACCAG
TCGGTTTTCCGATGCCAGTTCTATTTTGGATGCTATTGCCTCAACGATTCTTTCGCTCTTTTTAGATTTAACCATTGTTC
TTATGACAGGACTGATTTTAGGGCTTCAAAATATGCAACTCTTTCTTCTCGTTCTTTTGGCAATCCCACTTTATATTGTT
GTTATTATTATTTTTACTCCGCTTTTTGAAAGACAAAATCATGAAGTTATGCAAACCAATGCCATCTTAAATTCCTCAAT
TATTGAAGACATTAATGGGATTGAAACCATCAAAGCGCTCGCCAGTGAACAAGAGAGATATCAAAAAATTGACTACGAAT
TTGCAAGTTATCTAAAAGAGGCTTTCACTTTACAACAGTCAGAAGCCATTCAGACGGCAATAAAAACGACAGTACAACTT
GTACTAAATGTTCTTATTTTATGGTTTGGTGCAACTTTAGTCATGCATCAAAAAATTACCCTCGGACAACTCATTACTTT
TAATGCCTTGCTTTCTTACTTTACAAATCCAATTACTAATATCATTAACCTTCAAACAAAACTACAAAAGGCAAGGGTAG
CCAATGAACGATTAAATGAGGTCTATCTTATACCCAGTGAATTTGAAGAAAAGAAAACAGAACTGTCCCTCTCACATTTT
AATTTAAACATGTCTGAGATTTCATATCAATATGGTTTTGGCAGAAAAGTCTTATCTGAGATAAAACTGTCTATTAAAGA
AAATGAAAAGTTGACCATTGTTGGTATAAGCGGTTCAGGGAAGAGTACTCTTGTTAAATTATTGGTCAACTTCTTTCAAC
CCACTTCTGGTACCATTACTTTAGGTGGAATTGACCTTCAACAGTTTGATAAACATCAACTTCGACGATTAATCAACTAT
CTTCCCCAACAACCTTATATTTTCACAGGTTCAATTATGGATAATTTACTTTTAGGCGCTAGTGAAGCTACTTCACAAGA
AGAGATTATTAGAGCGGTGGAATTGGCAGAAATCCGTGCAGATATTGAACAAATGCAATTAGGTTATCAAACTGAACTCT
CAAGTGATGCAAGTAGTTTATCGGGAGGACAAAAACAGAGAATTGCGCTCGCTCGTGCCCTCCTTTCTCCTGCCAAAATA
CTCATCTTAGACGAAGCCACCAGTAATCTTGATATGATTACTGAAAAGAAAATATTAAAGAATTTGTTGGCACTAGATAA
GACAATTATTTTCATTGCTCACCGCCTCTCTGTAGCGGAAATGAGCCATCGTATCATTGTCATTGAACAAGGAAAAGTGA
TAGAAAGTGGTTCACATTCAGAACTGCTTGCTCAAAATGGCTTTTACGCACAACTTTACCATAACTAA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(169-437)

ABC transporter (ABC_tran)

(498-648)

Peptidase C39 family (Peptidase_C39)

(6-142)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus gordonii str. Challis substr. CH1

61.064

99.86

0.61
  comA Streptococcus mitis NCTC 12261

60.084

99.86

0.6
  comA Streptococcus mitis SK321

59.944

99.86

0.599
  comA Streptococcus pneumoniae Rx1

59.664

99.86

0.596
  comA Streptococcus pneumoniae D39

59.664

99.86

0.596
  comA Streptococcus pneumoniae R6

59.664

99.86

0.596
  comA Streptococcus pneumoniae TIGR4

59.384

99.86

0.593
  comA/nlmT Streptococcus mutans UA159

58.635

100

0.589