Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   LHUE1_RS02355 Genome accession   NZ_CP120687
Coordinates   530571..532763 (-) Length   730 a.a.
NCBI ID   WP_049171302.1    Uniprot ID   -
Organism   Lacticaseibacillus huelsenbergensis strain DSM 115425     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 525571..537763
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LHUE1_RS02340 (LHUE1_000468) - 526447..527424 (+) 978 WP_213291504.1 aldo/keto reductase -
  LHUE1_RS02345 (LHUE1_000469) - 527711..529066 (-) 1356 WP_049171308.1 threonine/serine exporter ThrE family protein -
  LHUE1_RS02350 (LHUE1_000470) - 529180..530559 (-) 1380 WP_049171305.1 bacteriocin secretion accessory protein -
  LHUE1_RS02355 (LHUE1_000471) comA 530571..532763 (-) 2193 WP_049171302.1 peptide cleavage/export ABC transporter Regulator
  LHUE1_RS02360 (LHUE1_000472) - 533077..533223 (-) 147 WP_191978410.1 bacteriocin-like peptide, LSEI_2386 family -
  LHUE1_RS02365 (LHUE1_000473) - 533392..534693 (+) 1302 WP_049171300.1 GHKL domain-containing protein -
  LHUE1_RS02370 (LHUE1_000474) - 534695..535501 (+) 807 WP_049171298.1 response regulator transcription factor -
  LHUE1_RS02375 (LHUE1_000475) - 535682..535963 (-) 282 WP_049171294.1 hypothetical protein -
  LHUE1_RS02380 (LHUE1_000476) - 537099..537257 (-) 159 WP_047105543.1 hypothetical protein -
  LHUE1_RS02385 (LHUE1_000477) - 537285..537482 (-) 198 WP_213291503.1 ComC/BlpC family peptide pheromone/bacteriocin -

Sequence

Protein


Download         Length: 730 a.a.        Molecular weight: 81556.09 Da        Isoelectric Point: 7.5911

>NTDB_id=807802 LHUE1_RS02355 WP_049171302.1 530571..532763(-) (comA) [Lacticaseibacillus huelsenbergensis strain DSM 115425]
MFKYKFKLGQAKYFKRYYTPQVDERDCGVAALNMLLKFHGSDYSLAHLRQLAKTDQEGTTALGIVRAAQELHFETKAVKA
DMTLFDLDDAPYPILVHVLKRGELSHYYVVFKATKDHILIGDPDPSVAMTWLSKEEFAKEWSGVAIFIAPEPQYQPRKED
KGSLFAFVPLLARQKVIIANIIVAALLITMISIVGSYFLQSIIDTYIPSAMRTTLGMIASGLILAYILQSVLTYGQNFLM
AVLGQRLSIDVILGYVRHLYELPMSFFATRRTGEIVSRFSDANKIIDALANTIMTLFLDVWIVLILGIVLGIQNTTLFLV
SLIAVPCYLVIVFAFQRPFNRLNQETMESNAILSSSIIEDLNGIETIKSLTGEKVSYERVDREFVTYLKKSFNYAKADQL
QQAIKGLLKLVLNVVVLWIGASLVMANKMSLGQMLTFNALLSYFTNPLESIINLQPKLQMAKVANNRLNEVYLVESEFKE
QRHLTDRSLIDGAIIVNDVSFKYGFGQDILKHVHLEVPANAKYTIVGMSGSGKSTLAKLLVGFYPVETGRGKITFNGAQI
DDVALTTLRQYIEYVPQEPFIFSGSVMENLTLGSRADLTQAQLEDACAVAEIATDIMNLPQMWQTKLTESGSILSGGQKQ
RLAIARALLSPAKVLIFDESTSSLDTITERRIVDRLLAMKDRTIIFVAHRLTIAAKTEQIVVMDHGAIVEQGNHAELLAK
QGYYARLVSE

Nucleotide


Download         Length: 2193 bp        

>NTDB_id=807802 LHUE1_RS02355 WP_049171302.1 530571..532763(-) (comA) [Lacticaseibacillus huelsenbergensis strain DSM 115425]
ATGTTCAAATACAAATTTAAACTAGGCCAAGCAAAATACTTCAAACGCTATTACACGCCTCAGGTGGATGAGCGTGATTG
CGGCGTTGCGGCGCTTAATATGTTGCTGAAGTTTCATGGGTCCGACTATTCGCTCGCACATTTACGGCAATTAGCAAAGA
CGGATCAGGAAGGAACAACAGCGTTAGGCATTGTTCGTGCTGCCCAGGAACTTCATTTTGAAACCAAGGCAGTTAAGGCG
GATATGACGTTGTTTGATTTGGATGATGCGCCATATCCGATTTTGGTTCATGTTTTGAAGCGCGGCGAGTTGTCGCATTA
TTATGTCGTGTTTAAGGCGACGAAGGATCATATCTTAATCGGTGATCCTGACCCTTCAGTCGCGATGACCTGGCTTTCAA
AAGAGGAGTTTGCCAAGGAGTGGTCGGGGGTGGCTATCTTTATTGCTCCTGAACCGCAATATCAACCGCGCAAAGAGGAC
AAAGGCAGTTTGTTTGCCTTCGTGCCGTTGCTCGCGCGGCAAAAAGTGATCATTGCCAATATTATTGTGGCGGCTTTGTT
GATCACGATGATTAGCATTGTTGGGTCGTATTTTCTGCAATCGATCATTGATACCTACATTCCAAGTGCCATGCGGACGA
CGTTAGGGATGATCGCCAGTGGGCTGATTCTCGCCTACATTCTCCAATCCGTTTTGACGTATGGCCAGAATTTCTTGATG
GCGGTTTTAGGCCAGCGATTGTCGATTGACGTTATTTTAGGTTACGTTCGGCATCTGTATGAATTACCCATGTCCTTTTT
TGCAACGCGCCGGACAGGGGAGATTGTGTCGCGGTTTTCGGATGCCAATAAAATTATCGATGCCTTGGCGAATACGATTA
TGACCCTGTTTCTTGACGTTTGGATCGTGCTTATTTTAGGCATTGTTTTGGGCATTCAAAATACCACATTGTTCCTGGTG
TCCTTAATTGCGGTGCCTTGTTACTTGGTGATTGTTTTCGCGTTTCAACGTCCTTTCAATCGGCTGAATCAAGAGACAAT
GGAAAGCAATGCCATTTTGAGCTCATCGATTATTGAGGATCTGAACGGTATTGAGACCATTAAGTCGCTGACAGGCGAAA
AAGTCAGTTATGAACGGGTTGACCGTGAATTCGTTACGTATTTAAAAAAGTCATTCAATTACGCGAAAGCTGACCAACTT
CAACAAGCCATCAAGGGGTTGCTGAAACTCGTCTTGAATGTGGTGGTGTTGTGGATTGGGGCGAGTCTGGTGATGGCTAA
CAAGATGAGCTTGGGGCAGATGCTGACGTTCAATGCCTTGCTGTCATACTTCACCAATCCGTTAGAAAGCATCATTAACT
TGCAACCAAAATTGCAAATGGCTAAGGTGGCGAATAATCGGCTGAATGAGGTTTATTTGGTTGAATCTGAGTTTAAAGAA
CAGCGCCATCTGACCGATCGCAGCTTGATCGATGGCGCCATCATTGTGAATGACGTTTCTTTTAAGTATGGATTTGGTCA
GGATATTTTGAAGCATGTCCATCTTGAAGTGCCCGCAAACGCTAAATACACGATTGTCGGCATGAGTGGGTCAGGTAAAT
CAACTTTGGCCAAATTATTGGTCGGTTTTTACCCGGTCGAAACAGGCAGGGGGAAAATCACTTTTAATGGCGCGCAGATC
GATGATGTGGCGCTCACGACGCTACGGCAATATATCGAGTATGTGCCGCAAGAACCATTTATTTTTTCCGGATCGGTGAT
GGAAAACTTAACGTTAGGCAGTCGTGCCGATTTGACGCAGGCGCAACTTGAAGACGCATGTGCTGTTGCGGAGATTGCCA
CGGATATTATGAATCTGCCGCAAATGTGGCAGACCAAGCTCACGGAAAGCGGGAGCATTTTATCAGGCGGGCAGAAGCAG
CGATTGGCGATTGCGCGAGCACTGTTGTCGCCGGCCAAAGTGCTGATTTTTGATGAGTCAACTAGCAGTCTGGATACCAT
TACAGAACGGCGGATTGTGGATCGATTGTTGGCAATGAAGGATCGAACGATTATTTTTGTTGCGCACCGACTCACCATCG
CGGCTAAAACCGAGCAGATCGTGGTGATGGATCACGGGGCAATTGTTGAGCAGGGCAATCATGCCGAACTGCTGGCGAAG
CAGGGATATTATGCGCGGTTGGTGAGTGAATAA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(180-448)

Peptidase C39 family (Peptidase_C39)

(16-152)

ABC transporter (ABC_tran)

(510-662)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

58.217

98.356

0.573
  comA Streptococcus pneumoniae Rx1

58.078

98.356

0.571
  comA Streptococcus pneumoniae D39

58.078

98.356

0.571
  comA Streptococcus pneumoniae R6

58.078

98.356

0.571
  comA Streptococcus mitis SK321

57.66

98.356

0.567
  comA Streptococcus pneumoniae TIGR4

57.66

98.356

0.567
  comA Streptococcus gordonii str. Challis substr. CH1

56.685

98.356

0.558
  comA/nlmT Streptococcus mutans UA159

54.986

98.904

0.544