Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   P3L36_RS02200 Genome accession   NZ_CP120654
Coordinates   373651..375606 (+) Length   651 a.a.
NCBI ID   WP_071664833.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain Guangzhou-SAG036     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 368651..380606
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P3L36_RS02185 (P3L36_02185) fmt 370629..371564 (+) 936 WP_000163893.1 methionyl-tRNA formyltransferase -
  P3L36_RS02190 (P3L36_02190) rsmB 371554..372876 (+) 1323 WP_001262601.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  P3L36_RS02195 (P3L36_02195) - 372914..373651 (+) 738 WP_000406233.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  P3L36_RS02200 (P3L36_02200) pknB 373651..375606 (+) 1956 WP_071664833.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  P3L36_RS02205 (P3L36_02205) liaF 375765..376460 (+) 696 WP_277687541.1 cell wall-active antibiotics response protein LiaF -
  P3L36_RS02210 (P3L36_02210) - 376457..377476 (+) 1020 WP_000716168.1 sensor histidine kinase -
  P3L36_RS02215 (P3L36_02215) - 377469..378110 (+) 642 WP_000357891.1 response regulator transcription factor -
  P3L36_RS02220 (P3L36_02220) - 378152..379552 (+) 1401 WP_000339135.1 Cof-type HAD-IIB family hydrolase -
  P3L36_RS02225 (P3L36_02225) - 379554..379910 (+) 357 WP_000689608.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 651 a.a.        Molecular weight: 70785.54 Da        Isoelectric Point: 9.6759

>NTDB_id=807514 P3L36_RS02200 WP_071664833.1 373651..375606(+) (pknB) [Streptococcus agalactiae strain Guangzhou-SAG036]
MIQIGKLFAGRYRILKSIGRGGMADVYLARDLILDNEEVAIKVLRTNYQTDQIAVARFQREARAMAELTHPNIVAIRDIG
EEDGQQFLVMEYVDGFDLKKYIQDNAPLSNNEVVRIMNEVLSAMSLAHQKGIVHRDLKPQNILLTKKGTVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSILAENKSVP
QALENIVIKATAKKLTDRYKTTYEMGRDLSTALSSTRHREPKLVFNDTESTKTLPKVTSTVSSLTTEQLLRNQKQAKTTE
KITPDSASNDKTKSKKKASHRLLGTIMKLFFALCVVGIIVFSYKILVSPTTIRVPDVSNKTVAQAKMTLENSGLKVGAIR
NIESDSVSEGLVVKTDPAAGRSRREGAKVNLYIATPNKSFTLGNYKEHNYKDILKDLQGKGVKKSLIKVKRKINNDYTTG
TILAQSLPEGTSFNPDGNKKLTLTVAVNDPMIMPDVTGMTVGEVIETLTDLGLDADNLVFYQMQNGVYQAVVTPPSSSKI
ASQDPYYGGEVGLRRGDKVKLYLLGSKTTNNSSSTPIDSSASSSTGTTTSDSVSSSTDASTSDSSSTSTSSSTLPSDSTT
NTGTANNPLTQ

Nucleotide


Download         Length: 1956 bp        

>NTDB_id=807514 P3L36_RS02200 WP_071664833.1 373651..375606(+) (pknB) [Streptococcus agalactiae strain Guangzhou-SAG036]
ATGATTCAGATTGGCAAATTATTTGCTGGTCGTTATCGGATCCTTAAATCAATCGGACGAGGTGGAATGGCGGATGTTTA
TCTAGCTCGAGATCTAATTTTAGATAATGAAGAGGTCGCAATAAAAGTATTGCGAACCAATTATCAAACAGATCAGATTG
CGGTTGCTCGCTTCCAGAGAGAAGCACGAGCAATGGCTGAGCTGACACATCCTAATATTGTCGCTATTCGTGATATAGGT
GAAGAAGACGGACAGCAGTTCTTAGTAATGGAATATGTTGATGGATTCGATTTAAAAAAGTATATTCAAGACAATGCACC
CCTATCAAATAATGAAGTTGTTCGAATCATGAATGAAGTCCTTTCAGCCATGTCACTGGCACATCAGAAAGGTATCGTAC
ACCGTGATTTAAAACCTCAAAATATTTTATTAACTAAAAAAGGGACTGTAAAAGTTACAGATTTCGGTATTGCGGTAGCG
TTTGCTGAAACTAGTTTAACGCAAACGAATTCTATGTTAGGTAGTGTTCATTATTTATCGCCAGAGCAGGCGCGTGGTTC
AAAAGCGACTGTTCAGAGTGATATTTATGCCATGGGAATCATGCTTTTTGAAATGTTAACTGGCCATATTCCTTATGATG
GGGATAGTGCAGTTACTATTGCCCTACAGCACTTCCAAAAACCACTACCATCAATCCTTGCAGAAAATAAAAGCGTTCCA
CAAGCTTTGGAAAACATTGTCATTAAAGCAACAGCTAAAAAGCTAACAGATCGCTATAAGACAACTTATGAGATGGGACG
TGATTTATCAACTGCTCTAAGCTCGACACGTCACCGTGAACCAAAACTTGTTTTTAATGATACTGAGAGTACTAAGACAC
TACCAAAAGTAACATCTACAGTATCATCTTTAACGACAGAACAACTGTTGCGTAATCAAAAACAGGCCAAAACAACAGAA
AAAATAACTCCTGATTCTGCGAGTAACGATAAAACGAAGTCTAAAAAGAAGGCTTCTCATCGACTTCTTGGTACAATCAT
GAAATTATTCTTTGCACTCTGTGTTGTAGGAATAATTGTATTTTCTTATAAAATTTTAGTAAGTCCTACGACTATTCGTG
TTCCAGATGTTAGCAACAAAACAGTAGCTCAAGCAAAAATGACATTGGAAAATTCTGGATTGAAAGTAGGAGCTATTCGT
AATATTGAGAGTGATAGTGTTTCAGAAGGCCTTGTCGTAAAAACAGACCCTGCTGCAGGACGTTCTCGTAGAGAAGGGGC
TAAAGTTAATCTTTATATTGCCACTCCAAACAAGAGTTTCACTCTAGGTAATTATAAGGAACATAATTACAAAGATATCC
TCAAAGATCTTCAAGGCAAAGGTGTTAAAAAATCTTTAATCAAGGTTAAGCGTAAAATTAATAATGATTATACTACTGGT
ACAATCTTAGCACAGTCGCTTCCAGAAGGAACATCTTTTAATCCTGATGGTAATAAGAAATTAACACTTACGGTTGCTGT
TAATGATCCAATGATTATGCCTGATGTAACAGGTATGACAGTTGGAGAAGTAATAGAAACCTTGACAGACCTCGGATTAG
ATGCAGATAATCTTGTCTTCTATCAAATGCAAAATGGCGTTTATCAAGCAGTAGTAACACCTCCATCTTCAAGTAAGATA
GCAAGTCAGGATCCTTATTACGGAGGAGAAGTTGGATTAAGGAGAGGAGATAAAGTTAAGCTGTATCTTCTTGGTTCTAA
AACAACAAATAACTCATCATCTACGCCAATAGATTCTTCGGCTTCAAGCTCAACAGGAACAACTACCTCGGATTCTGTAA
GCTCATCAACGGATGCTAGCACTTCTGATAGTAGTAGCACTTCTACAAGTAGTTCAACACTACCAAGTGATAGTACAACT
AATACAGGAACAGCTAACAATCCATTAACTCAATAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-254)

PASTA domain (PASTA)

(511-583)

PASTA domain (PASTA)

(373-434)

PASTA domain (PASTA)

(441-506)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

60.959

89.708

0.547
  stkP/pknB Streptococcus salivarius strain HSISS4

60.727

88.786

0.539
  stkP Streptococcus pneumoniae TIGR4

59.612

79.109

0.472
  stkP Streptococcus pneumoniae D39

59.417

79.109

0.47
  stkP Streptococcus pneumoniae R6

59.417

79.109

0.47
  stkP Streptococcus pneumoniae Rx1

59.223

79.109

0.469