Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   P3L36_RS00410 Genome accession   NZ_CP120654
Coordinates   64486..65397 (+) Length   303 a.a.
NCBI ID   WP_000912100.1    Uniprot ID   A0A0E1EEL0
Organism   Streptococcus agalactiae strain Guangzhou-SAG036     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 59486..70397
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P3L36_RS00390 (P3L36_00390) purK 59713..60786 (+) 1074 WP_277687465.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  P3L36_RS00395 (P3L36_00395) - 60796..62040 (+) 1245 WP_000522367.1 DUF4041 domain-containing protein -
  P3L36_RS00400 (P3L36_00400) - 62172..63017 (+) 846 WP_000613836.1 hypothetical protein -
  P3L36_RS00405 (P3L36_00405) purB 63035..64333 (+) 1299 WP_000625675.1 adenylosuccinate lyase -
  P3L36_RS00410 (P3L36_00410) comR 64486..65397 (+) 912 WP_000912100.1 helix-turn-helix domain-containing protein Regulator
  P3L36_RS00415 (P3L36_00415) ruvB 65694..66692 (+) 999 WP_001873969.1 Holliday junction branch migration DNA helicase RuvB -
  P3L36_RS00420 (P3L36_00420) - 66844..67281 (+) 438 WP_000754819.1 low molecular weight protein-tyrosine-phosphatase -
  P3L36_RS00425 (P3L36_00425) - 67288..67668 (+) 381 WP_000787702.1 membrane protein -
  P3L36_RS00430 (P3L36_00430) - 67665..69443 (+) 1779 WP_001220913.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 303 a.a.        Molecular weight: 35654.11 Da        Isoelectric Point: 5.6370

>NTDB_id=807501 P3L36_RS00410 WP_000912100.1 64486..65397(+) (comR) [Streptococcus agalactiae strain Guangzhou-SAG036]
MLKHFGSKVRNLRVTRNITREDFCGDETELSVRQLARIESGQSIPNLTKAHYIAKQLNVKLDILTGGESLELPKRYKELK
YLILRIPTYADAERLKLRECQFDHIFEEFYDNLPEDECLAIDSLQAKFEVYQTGDINFGVEVLCECFDKVKYKEKYTLND
LIIIDLFLTCAVVSKFNNRAFTKEVFQTICKTLISQNHKLTAEDLFWFNHVLLNCVFVGLCLNSEECLAEMLEVSRQTMV
STHDFHKMPLYFMYQWKYFITIDNDIKSAENAYQQSIMFSKMIDDKHLIKKLELEWQEDITGH

Nucleotide


Download         Length: 912 bp        

>NTDB_id=807501 P3L36_RS00410 WP_000912100.1 64486..65397(+) (comR) [Streptococcus agalactiae strain Guangzhou-SAG036]
ATGTTAAAACATTTTGGTAGTAAAGTAAGAAATTTGAGAGTAACTAGAAATATTACTCGCGAAGATTTTTGTGGTGATGA
AACTGAGTTATCTGTAAGACAATTAGCTAGGATTGAAAGTGGACAGTCAATCCCAAACTTGACTAAAGCTCACTACATAG
CTAAACAATTGAATGTAAAATTAGATATTTTAACAGGAGGAGAGAGCTTAGAATTACCTAAACGGTATAAAGAGTTGAAG
TATTTGATTTTAAGAATTCCAACTTATGCAGATGCTGAACGATTAAAATTAAGAGAATGTCAGTTTGATCATATTTTCGA
AGAATTCTATGATAATCTTCCAGAAGACGAGTGCTTAGCAATTGACAGTTTACAAGCTAAATTTGAAGTCTATCAAACAG
GAGACATTAATTTTGGTGTGGAGGTTTTATGCGAATGCTTTGATAAAGTAAAATATAAAGAAAAATATACTCTTAATGAT
TTGATTATCATAGATTTGTTTTTAACTTGTGCAGTTGTATCTAAATTTAACAATAGAGCATTTACTAAAGAAGTATTTCA
AACTATATGTAAAACTTTGATAAGTCAGAACCACAAACTTACAGCAGAAGATTTGTTTTGGTTTAATCATGTACTCCTGA
ATTGTGTATTTGTTGGACTTTGTTTAAATAGTGAAGAGTGTCTTGCAGAAATGTTAGAAGTTAGCCGACAAACGATGGTG
TCAACACATGATTTTCATAAAATGCCTTTATATTTTATGTACCAATGGAAATACTTCATTACAATTGACAATGATATAAA
GTCTGCAGAAAATGCTTACCAACAATCAATTATGTTTTCAAAAATGATTGATGACAAGCATCTAATTAAAAAATTAGAAT
TGGAGTGGCAAGAAGATATAACAGGACATTGA

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(73-296)

Helix-turn-helix (HTH_3)

(10-64)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E1EEL0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS315

52.667

99.01

0.521
  comR Streptococcus mutans UA159

44.816

98.68

0.442
  comR Streptococcus pyogenes MGAS8232

42.904

100

0.429
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

44.33

96.04

0.426