Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   P3R60_RS09315 Genome accession   NZ_CP120510
Coordinates   1795377..1796093 (+) Length   238 a.a.
NCBI ID   WP_104968219.1    Uniprot ID   A0A2L0D503
Organism   Streptococcus pluranimalium strain SP21-2     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1790377..1801093
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P3R60_RS09290 - 1790629..1791675 (+) 1047 WP_104968224.1 LLM class flavin-dependent oxidoreductase -
  P3R60_RS09295 - 1791811..1792008 (-) 198 WP_104968223.1 hypothetical protein -
  P3R60_RS09300 - 1792588..1793559 (-) 972 WP_104968222.1 anti sigma factor C-terminal domain-containing protein -
  P3R60_RS09305 - 1793537..1794052 (-) 516 WP_104968221.1 RNA polymerase sigma factor -
  P3R60_RS09310 - 1794392..1795240 (+) 849 WP_316606277.1 aldo/keto reductase -
  P3R60_RS09315 vicR 1795377..1796093 (+) 717 WP_104968219.1 response regulator transcription factor Regulator
  P3R60_RS09320 pnpS 1796093..1797433 (+) 1341 WP_278023834.1 two-component system histidine kinase PnpS -
  P3R60_RS09330 - 1799080..1799961 (+) 882 WP_316606279.1 substrate-binding domain-containing protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27528.83 Da        Isoelectric Point: 5.4806

>NTDB_id=805881 P3R60_RS09315 WP_104968219.1 1795377..1796093(+) (vicR) [Streptococcus pluranimalium strain SP21-2]
MQKRVLIVDDEPHILTLVSYHLAKEGFEVTTVEDGRSALELGQGQPFDFIVLDIMLPQLDGVEVCKRLRKAGIETPILML
SAKGEEFDKVLALELGADDYMTKPFSPRELLARIKAILRRTEKNQLSELLQEEDQSDTKFQVADLTVYLERHQIYKADRE
ISLTPKEFELLVYLLKHPRMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKAPAIIKTVRGYGYKFEGDK

Nucleotide


Download         Length: 717 bp        

>NTDB_id=805881 P3R60_RS09315 WP_104968219.1 1795377..1796093(+) (vicR) [Streptococcus pluranimalium strain SP21-2]
ATGCAAAAGCGTGTTTTAATCGTGGATGATGAGCCACATATTCTCACTTTGGTTTCCTACCATTTAGCTAAGGAAGGTTT
TGAGGTAACGACTGTCGAAGATGGTCGGTCTGCCCTAGAATTGGGACAAGGTCAGCCCTTTGATTTTATTGTTTTAGATA
TCATGTTGCCACAACTTGATGGTGTTGAAGTTTGTAAAAGACTGCGAAAAGCCGGTATCGAAACCCCTATCCTCATGCTG
TCAGCTAAGGGAGAGGAATTTGATAAGGTTTTAGCTCTGGAATTAGGGGCGGATGACTACATGACCAAGCCCTTTAGTCC
GCGGGAACTTCTGGCTAGGATCAAGGCAATCCTGCGTCGGACTGAGAAAAATCAACTGTCAGAATTGCTCCAAGAAGAAG
ACCAGTCTGATACGAAATTTCAAGTTGCAGACTTAACGGTCTATTTGGAGCGTCATCAGATTTACAAGGCAGATCGAGAG
ATTAGCTTGACGCCTAAAGAGTTTGAACTCTTGGTTTATCTTTTGAAGCATCCTCGTATGACGCTGACCAGAGAACGCCT
GTTGGAGCGAATTTGGGGCTATGATTTTGGGCAGGAGACCCGTTTAGTGGATGTGCATATCGGTAAGTTACGTGAAAAAA
TCGAGGATAATCCCAAGGCACCTGCCATTATCAAAACAGTCAGAGGTTACGGCTACAAGTTTGAAGGAGACAAGTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-115)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(159-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2L0D503

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

50.435

96.639

0.487
  micA Streptococcus pneumoniae Cp1015

50

96.639

0.483
  covR Streptococcus salivarius strain HSISS4

42.241

97.479

0.412
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.126

97.059

0.399
  scnR Streptococcus mutans UA159

37.021

98.739

0.366