Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   P3R60_RS08430 Genome accession   NZ_CP120510
Coordinates   1634809..1636692 (+) Length   627 a.a.
NCBI ID   WP_316606208.1    Uniprot ID   -
Organism   Streptococcus pluranimalium strain SP21-2     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1629809..1641692
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P3R60_RS08415 fmt 1631770..1632711 (+) 942 WP_218653590.1 methionyl-tRNA formyltransferase -
  P3R60_RS08420 rsmB 1632701..1634023 (+) 1323 WP_316606207.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  P3R60_RS08425 - 1634072..1634809 (+) 738 WP_316606811.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  P3R60_RS08430 stkP/pknB 1634809..1636692 (+) 1884 WP_316606208.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  P3R60_RS08435 liaF 1636857..1637555 (+) 699 WP_316606209.1 cell wall-active antibiotics response protein LiaF -
  P3R60_RS08440 - 1637552..1638550 (+) 999 WP_316606210.1 sensor histidine kinase -
  P3R60_RS08445 - 1638543..1639181 (+) 639 WP_316606211.1 response regulator transcription factor -
  P3R60_RS08450 - 1639229..1640629 (+) 1401 WP_316606212.1 Cof-type HAD-IIB family hydrolase -
  P3R60_RS08455 - 1640629..1640988 (+) 360 WP_316606213.1 S1 RNA-binding domain-containing protein -
  P3R60_RS08460 - 1641064..1641287 (+) 224 Protein_1620 hypothetical protein -

Sequence

Protein


Download         Length: 627 a.a.        Molecular weight: 68189.35 Da        Isoelectric Point: 4.7694

>NTDB_id=805871 P3R60_RS08430 WP_316606208.1 1634809..1636692(+) (stkP/pknB) [Streptococcus pluranimalium strain SP21-2]
MIQIGKLFAGRYRILKSIGRGGMADVYLAHDLILDNEEVAIKVLRTNYQTDQIAVARFQREARAMAELNHPNIVAIRDIG
EEDGQQFLAMEYVNGPDLKKYIQDHAPLSNTETVRIMSEVLSAMQLAHQKGIVHRDLKPQNVLLTKDGVAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTCHIPFDGDSAVTIALQHFQKPLPSIIFENRNVP
QALENVVIKATAKKLGDRYVSTTDMYQDLGTSLDSRRARESKLVFQDTTDTKTLPKIEPSPVKEAPKAAVAPDSVEVPKE
KEASKKEASTPPSSKKSKKPFWQRLFRFFILALVLLLAGFAFFFMSSSNDSATVPDVSGQTIQEAQATLEEAGLTVGAVS
RKESDSVEEGKVISTTPKSGTTQKEGSEVDLLVSKGSKRFVMTDYTGMSYRDAVSDLTENYGLSKNQIVKKEVTNNQYEP
GEIISQTPEAGEDFNPSGNDKIIFEVATASTVTIPTLVGYSYADAKNALLDLGFKASQIQTDSDQPSSSATVYAQYPYAG
TSVELSSGETVTLYLTTPEPSSTQPSSSSEELDTDSSNQTSSSSSSSSSNHSTEATGDANSQPETTD

Nucleotide


Download         Length: 1884 bp        

>NTDB_id=805871 P3R60_RS08430 WP_316606208.1 1634809..1636692(+) (stkP/pknB) [Streptococcus pluranimalium strain SP21-2]
ATGATCCAAATCGGCAAATTATTTGCTGGGCGTTATCGTATTTTAAAATCTATCGGTCGCGGTGGTATGGCTGATGTTTA
TTTGGCACATGATTTGATTTTGGATAATGAAGAAGTAGCGATTAAGGTGCTTCGAACCAATTATCAAACAGATCAAATTG
CAGTCGCGCGTTTCCAGAGAGAAGCGCGTGCGATGGCTGAATTAAATCATCCTAACATTGTAGCTATCAGAGATATCGGC
GAAGAAGATGGACAACAATTTCTTGCCATGGAATACGTTAATGGTCCAGATTTAAAGAAGTATATTCAAGATCATGCACC
TCTTTCTAATACTGAGACAGTTCGTATCATGAGTGAGGTGTTATCAGCTATGCAGCTGGCTCATCAAAAAGGAATTGTTC
ATCGTGACTTGAAGCCACAGAATGTTCTTTTGACAAAAGACGGAGTAGCTAAGGTAACTGATTTTGGGATTGCTGTAGCC
TTTGCAGAGACAAGTTTGACACAGACAAATTCGATGTTAGGAAGTGTTCATTACTTGTCACCAGAACAAGCACGAGGCTC
TAAAGCAACGATACAAAGTGATATTTATGCTATGGGTATCATGTTGTTTGAAATGTTGACTTGTCATATCCCATTTGATG
GTGATAGTGCTGTTACGATTGCATTGCAACACTTTCAGAAACCTTTGCCATCGATTATTTTTGAAAATCGAAATGTTCCA
CAAGCTTTGGAGAATGTTGTTATCAAAGCAACTGCTAAAAAGCTCGGAGATCGCTATGTATCAACGACCGATATGTATCA
AGATTTAGGGACATCCCTAGATTCGCGCCGTGCTAGAGAATCAAAGTTAGTTTTTCAAGATACAACAGATACTAAGACAT
TACCTAAAATTGAGCCTTCACCTGTTAAAGAGGCACCTAAAGCAGCAGTTGCTCCGGATAGTGTCGAAGTGCCTAAAGAA
AAGGAAGCTTCTAAAAAAGAAGCCTCTACACCGCCGTCATCTAAAAAGTCTAAGAAACCTTTTTGGCAACGTCTATTCAG
ATTTTTCATTTTGGCCCTCGTTTTATTACTAGCCGGTTTTGCATTCTTCTTTATGTCAAGTAGCAATGATAGTGCAACAG
TTCCTGATGTCTCAGGGCAAACAATCCAAGAAGCTCAAGCCACTCTAGAAGAGGCTGGTTTGACTGTAGGAGCTGTTTCT
CGTAAAGAAAGTGACAGTGTTGAGGAAGGAAAGGTCATTTCAACAACACCGAAATCAGGAACCACTCAAAAAGAGGGAAG
CGAAGTTGATCTACTAGTTTCAAAAGGTTCTAAACGCTTTGTTATGACAGATTATACCGGGATGTCATATAGGGATGCTG
TTAGTGATTTGACGGAAAATTATGGTTTGTCTAAAAATCAAATTGTCAAAAAAGAAGTTACAAATAATCAGTATGAACCG
GGAGAAATTATTAGTCAGACTCCAGAAGCTGGCGAAGATTTTAACCCTTCAGGTAATGATAAGATTATTTTTGAAGTAGC
AACAGCTTCAACAGTAACAATACCAACCTTGGTTGGTTACAGTTATGCAGATGCCAAGAATGCTTTATTAGACCTAGGAT
TTAAAGCTTCTCAGATTCAGACAGATTCAGATCAACCGTCGTCATCGGCAACGGTTTATGCACAATACCCATATGCAGGG
ACGTCTGTTGAACTCTCATCTGGAGAAACGGTAACATTGTATCTAACAACTCCTGAGCCATCATCGACGCAACCGTCATC
ATCTTCTGAGGAGTTAGATACGGATAGTAGTAATCAGACCTCTTCATCAAGTAGTTCTTCTAGTTCCAACCATTCAACGG
AAGCAACAGGTGATGCAAACAGCCAACCAGAAACTACTGACTAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-227)

PASTA domain (PASTA)

(441-507)

PASTA domain (PASTA)

(512-576)

PASTA domain (PASTA)

(373-435)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

62.969

93.461

0.589
  pknB Streptococcus mutans UA159

61.017

94.099

0.574
  stkP Streptococcus pneumoniae TIGR4

52.736

96.172

0.507
  stkP Streptococcus pneumoniae D39

52.57

96.172

0.506
  stkP Streptococcus pneumoniae R6

52.57

96.172

0.506
  stkP Streptococcus pneumoniae Rx1

52.405

96.172

0.504