Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   P3R60_RS00975 Genome accession   NZ_CP120510
Coordinates   199256..199927 (+) Length   223 a.a.
NCBI ID   WP_104967889.1    Uniprot ID   A0A2L0D3Z7
Organism   Streptococcus pluranimalium strain SP21-2     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 194256..204927
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P3R60_RS00960 pstB 194917..195675 (+) 759 WP_104967892.1 phosphate ABC transporter ATP-binding protein PstB -
  P3R60_RS00965 phoU 195701..196354 (+) 654 WP_115130300.1 phosphate signaling complex protein PhoU -
  P3R60_RS00970 - 196476..199010 (+) 2535 WP_316606433.1 M1 family metallopeptidase -
  P3R60_RS00975 ciaR 199256..199927 (+) 672 WP_104967889.1 response regulator transcription factor Regulator
  P3R60_RS00980 ciaH 199920..201224 (+) 1305 WP_218654370.1 cell wall metabolism sensor histidine kinase WalK Regulator
  P3R60_RS00985 rpsT 201697..201945 (-) 249 WP_104967887.1 30S ribosomal protein S20 -
  P3R60_RS00990 coaA 201998..202918 (-) 921 WP_316606434.1 type I pantothenate kinase -
  P3R60_RS00995 - 203045..203632 (+) 588 WP_316606435.1 class I SAM-dependent methyltransferase -
  P3R60_RS01000 - 204212..204601 (+) 390 WP_316606436.1 cytidine deaminase -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 25377.22 Da        Isoelectric Point: 4.4478

>NTDB_id=805834 P3R60_RS00975 WP_104967889.1 199256..199927(+) (ciaR) [Streptococcus pluranimalium strain SP21-2]
MIKLLLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGLYEAESGVYDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTA
KEGLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKLTDHTIVYGNISVDTTINRVTVDGKEVEFLGKEFELLMY
FLQNQNVILPKTQIFDRLWGFDSDTTLSVVEVYVSKIRKKLKGTSFADHLQTLRSVGYILKDA

Nucleotide


Download         Length: 672 bp        

>NTDB_id=805834 P3R60_RS00975 WP_104967889.1 199256..199927(+) (ciaR) [Streptococcus pluranimalium strain SP21-2]
ATGATAAAATTACTCTTGGTTGAAGATGATTTGAGTTTGTCCAATTCTGTATTTGATTTTCTGGATGATTTTGCAGATGT
GATGCAGGTCTTTGATGGGGAAGAAGGATTGTATGAAGCTGAATCTGGTGTTTATGATCTTATTTTACTAGATCTTATGC
TTCCAGAAAAAAATGGTTTTCAAGTGCTAAAAGAGCTTCGAGAAAAAGGGATAACAACGCCTGTTTTAATTATGACAGCA
AAGGAAGGGTTGGATGATAAGGGACATGGTTTTGAGTTAGGAGCAGATGATTATTTAACTAAGCCATTTTATCTAGAAGA
ATTAAAAATGAGAATCCAAGCCTTACTTAAACGTTCTGGAAAGCTGACCGATCATACCATCGTATACGGTAATATTAGCG
TTGACACGACAATTAATCGTGTTACAGTAGATGGCAAAGAAGTAGAATTTTTAGGCAAAGAATTTGAATTGTTAATGTAC
TTTCTACAAAACCAAAATGTTATTTTACCTAAAACACAGATTTTTGATCGTTTATGGGGATTTGATAGCGATACAACGCT
TTCGGTTGTTGAAGTTTATGTGTCAAAAATCCGTAAAAAACTTAAAGGAACGAGTTTTGCAGATCATTTACAGACTTTAA
GAAGTGTTGGTTATATTTTAAAAGATGCATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2L0D3Z7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

87.444

100

0.874
  ciaR Streptococcus pneumoniae Rx1

86.547

100

0.865
  ciaR Streptococcus pneumoniae D39

86.547

100

0.865
  ciaR Streptococcus pneumoniae R6

86.547

100

0.865
  ciaR Streptococcus pneumoniae TIGR4

86.547

100

0.865
  covR Lactococcus lactis subsp. lactis strain DGCC12653

35.841

100

0.363