Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   RJW53_RS02255 Genome accession   NZ_CP134488
Coordinates   431491..432135 (-) Length   214 a.a.
NCBI ID   WP_012027589.1    Uniprot ID   A0A0H3MWP6
Organism   Streptococcus suis strain NLS50     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 426491..437135
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RJW53_RS02235 (RJW53_02235) nadE 426600..427424 (-) 825 WP_004194617.1 ammonia-dependent NAD(+) synthetase -
  RJW53_RS02240 (RJW53_02240) - 427437..428897 (-) 1461 WP_012027590.1 nicotinate phosphoribosyltransferase -
  RJW53_RS02245 (RJW53_02245) cclA/cilC 429005..429556 (-) 552 WP_311047960.1 prepilin peptidase Machinery gene
  RJW53_RS02250 (RJW53_02250) - 429619..431340 (-) 1722 WP_074389404.1 IS1634 family transposase -
  RJW53_RS02255 (RJW53_02255) cclA/cilC 431491..432135 (-) 645 WP_012027589.1 A24 family peptidase Machinery gene
  RJW53_RS02260 (RJW53_02260) - 432257..432811 (+) 555 WP_004194627.1 class I SAM-dependent methyltransferase -
  RJW53_RS02265 (RJW53_02265) - 432827..433606 (-) 780 WP_012027588.1 ABC transporter ATP-binding protein -
  RJW53_RS02270 (RJW53_02270) - 433739..435076 (+) 1338 WP_074389850.1 hemolysin family protein -
  RJW53_RS02275 (RJW53_02275) pflA 435197..435988 (+) 792 WP_012027587.1 pyruvate formate-lyase-activating protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24215.33 Da        Isoelectric Point: 8.4760

>NTDB_id=804081 RJW53_RS02255 WP_012027589.1 431491..432135(-) (cclA/cilC) [Streptococcus suis strain NLS50]
MKTIILFFLGASIGSFLGLVIDRFPEQSIIAPSSHCNACKRRLKAWDLIPVLSQLSTKSKCRYCKAKIPYWYLGLEFLAG
LVVLLCHFQVLNLTETILILAGLVLTIYDIKHQEYPFAVWLIFTFIALILSQLNWLFCGFLLLAYLTEKWQINIGSGDFL
YLASLALICGFTELLWIIQISSLLGLLVFAIFKPKSIPYVPLLFLSSIPIILCT

Nucleotide


Download         Length: 645 bp        

>NTDB_id=804081 RJW53_RS02255 WP_012027589.1 431491..432135(-) (cclA/cilC) [Streptococcus suis strain NLS50]
ATGAAGACAATTATCCTATTTTTCCTTGGAGCTTCTATCGGCTCCTTCTTGGGATTGGTCATCGACCGTTTCCCTGAACA
GTCCATTATCGCCCCCTCTAGTCACTGCAATGCCTGCAAACGACGGCTCAAGGCCTGGGACTTAATTCCAGTCCTATCCC
AGCTTTCGACAAAATCCAAATGCCGTTACTGCAAGGCGAAGATACCTTATTGGTATCTGGGATTGGAATTCTTAGCCGGT
CTAGTTGTCCTGCTCTGCCATTTTCAAGTCCTAAACCTAACCGAAACCATTCTCATCTTGGCAGGACTAGTTTTGACCAT
TTACGACATCAAGCATCAGGAATATCCTTTTGCTGTCTGGCTCATTTTTACTTTTATAGCTCTGATACTCTCCCAGCTCA
ACTGGCTTTTCTGTGGCTTTTTACTCTTGGCCTATCTGACTGAAAAATGGCAAATCAATATTGGTTCTGGTGACTTTCTC
TATCTGGCAAGTTTGGCCTTAATATGTGGATTTACAGAACTCCTCTGGATTATCCAGATTAGTTCCCTCCTAGGGCTTCT
TGTCTTCGCCATTTTCAAACCCAAGTCTATTCCCTACGTACCACTCCTATTTCTTTCAAGTATTCCTATCATTCTGTGCA
CCTAA

Domains

Predicted by InterProScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(9-88)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3MWP6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis SK321

49.528

99.065

0.491
  cclA/cilC Streptococcus pneumoniae Rx1

49.029

96.262

0.472
  cclA/cilC Streptococcus pneumoniae D39

49.029

96.262

0.472
  cclA/cilC Streptococcus pneumoniae R6

49.029

96.262

0.472
  cclA/cilC Streptococcus pneumoniae TIGR4

47.17

99.065

0.467
  cclA/cilC Streptococcus mitis NCTC 12261

45.755

99.065

0.453