Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   RJW49_RS05155 Genome accession   NZ_CP134477
Coordinates   974310..974981 (+) Length   223 a.a.
NCBI ID   WP_074393444.1    Uniprot ID   -
Organism   Streptococcus suis strain NLS40     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 969310..979981
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RJW49_RS05130 (RJW49_05130) pstB 969689..970492 (+) 804 WP_002940866.1 phosphate ABC transporter ATP-binding protein PstB -
  RJW49_RS05135 (RJW49_05135) pstB 970504..971262 (+) 759 WP_002937614.1 phosphate ABC transporter ATP-binding protein PstB -
  RJW49_RS05140 (RJW49_05140) phoU 971291..971947 (+) 657 WP_012028219.1 phosphate signaling complex protein PhoU -
  RJW49_RS05145 (RJW49_05145) - 972149..973351 (-) 1203 WP_311048118.1 IS110 family transposase -
  RJW49_RS05150 (RJW49_05150) - 973736..974116 (+) 381 WP_012027076.1 hypothetical protein -
  RJW49_RS05155 (RJW49_05155) ciaR 974310..974981 (+) 672 WP_074393444.1 response regulator transcription factor Regulator
  RJW49_RS05160 (RJW49_05160) ciaH 974974..976353 (+) 1380 WP_012775588.1 cell wall metabolism sensor histidine kinase WalK Regulator
  RJW49_RS05165 (RJW49_05165) - 976684..977208 (+) 525 WP_243665367.1 hypothetical protein -
  RJW49_RS05170 (RJW49_05170) - 977280..977912 (+) 633 WP_243665368.1 transglutaminase domain-containing protein -
  RJW49_RS05175 (RJW49_05175) rpsT 978175..978423 (-) 249 WP_012027069.1 30S ribosomal protein S20 -
  RJW49_RS05180 (RJW49_05180) coaA 978482..979402 (-) 921 WP_012027068.1 type I pantothenate kinase -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 25275.98 Da        Isoelectric Point: 4.2132

>NTDB_id=803904 RJW49_RS05155 WP_074393444.1 974310..974981(+) (ciaR) [Streptococcus suis strain NLS40]
MIKILLVEDDLSLSNSVFDFLDDFADVMQVFDGEDGVYEAETGVYDLILLDLMLPEKDGFQVLKELREKGVTTPVLITTA
KESLEDKGHGFELGADDYLTKPFYLEELKMRIQALLKRAGKFNENTLTFGDVTVDLSTNMTMVNGEEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTTFGENLQTLRSVGYILKNA

Nucleotide


Download         Length: 672 bp        

>NTDB_id=803904 RJW49_RS05155 WP_074393444.1 974310..974981(+) (ciaR) [Streptococcus suis strain NLS40]
ATGATTAAAATATTGTTAGTGGAAGATGATTTAAGTCTATCAAATTCTGTTTTCGATTTCTTAGATGATTTTGCGGATGT
TATGCAGGTTTTTGATGGTGAAGATGGCGTTTATGAGGCGGAAACAGGCGTTTATGATTTGATTCTTTTGGATTTAATGT
TACCTGAAAAAGACGGCTTTCAAGTCTTGAAAGAGTTACGTGAAAAGGGGGTTACGACACCAGTTCTGATTACAACAGCC
AAGGAAAGTCTAGAGGATAAAGGCCATGGTTTTGAATTGGGGGCTGATGACTATTTGACAAAACCGTTTTATTTAGAAGA
ATTGAAGATGCGAATTCAAGCTCTATTAAAACGAGCGGGTAAGTTTAATGAAAACACACTAACCTTTGGAGATGTGACAG
TTGACCTATCTACAAATATGACGATGGTAAATGGCGAAGAAGTTGAACTGTTAGGAAAAGAATTTGATCTACTAGTTTAT
TTCTTGCAAAATCAAAATGTTATTTTGCCAAAAACACAAATTTTTGACCGTATTTGGGGCTTTGACAGTGATACTACAAT
TTCAGTAGTAGAAGTATATGTTTCTAAAATTAGGAAAAAGTTGAAAGGAACGACTTTTGGGGAAAATCTTCAAACCCTGC
GTAGTGTCGGATACATTCTAAAAAATGCCTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

89.686

100

0.897
  ciaR Streptococcus pneumoniae Rx1

87.892

100

0.879
  ciaR Streptococcus pneumoniae D39

87.892

100

0.879
  ciaR Streptococcus pneumoniae R6

87.892

100

0.879
  ciaR Streptococcus pneumoniae TIGR4

87.892

100

0.879
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.496

100

0.39
  vicR Streptococcus mutans UA159

35.043

100

0.368