Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   RJW49_RS00320 Genome accession   NZ_CP134477
Coordinates   54980..55879 (+) Length   299 a.a.
NCBI ID   WP_044678694.1    Uniprot ID   -
Organism   Streptococcus suis strain NLS40     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 49980..60879
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RJW49_RS00300 (RJW49_00300) purB 50871..52163 (+) 1293 WP_014735227.1 adenylosuccinate lyase -
  RJW49_RS00305 (RJW49_00305) tnpA 52354..52867 (+) 514 Protein_40 IS200/IS605 family transposase -
  RJW49_RS00310 (RJW49_00310) ruvB 53029..54030 (+) 1002 WP_014735241.1 Holliday junction branch migration DNA helicase RuvB Machinery gene
  RJW49_RS00315 (RJW49_00315) - 54098..54733 (+) 636 WP_014735242.1 HAD-IA family hydrolase -
  RJW49_RS00320 (RJW49_00320) comR 54980..55879 (+) 900 WP_044678694.1 helix-turn-helix domain-containing protein Regulator
  RJW49_RS00325 (RJW49_00325) - 56305..57507 (+) 1203 WP_079759536.1 IS110 family transposase -
  RJW49_RS00330 (RJW49_00330) - 58062..58999 (-) 938 Protein_45 IS4 family transposase -
  RJW49_RS00335 (RJW49_00335) - 59136..60356 (+) 1221 WP_074393600.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35435.33 Da        Isoelectric Point: 4.6492

>NTDB_id=803863 RJW49_RS00320 WP_044678694.1 54980..55879(+) (comR) [Streptococcus suis strain NLS40]
MNDKEFGQRVRQLRESASMTREQFCDDELELSVRQLTRIEAGTSKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEDLAEKRDAMMTEIYDDYYDELPEEEKIAIDAIQSRIDTLESGTAGFGKEILEDYFEQIFRKRKYELND
LLIVRLHLEYVRLSSCDSEIFRQFLKIIEHLHEQINIINSNDLFVLRDTLLSCVNILGSKKYYEPIPKIFDSVDKIIQST
QDFQKKPIVSVLKWKYALFVDKDRDEAEKHYLDAVLFAKLIENRELEQKIEEDWRVDNQ

Nucleotide


Download         Length: 900 bp        

>NTDB_id=803863 RJW49_RS00320 WP_044678694.1 54980..55879(+) (comR) [Streptococcus suis strain NLS40]
ATGAACGATAAGGAATTTGGACAGCGTGTACGTCAATTACGAGAATCTGCTAGTATGACACGTGAACAGTTTTGTGACGA
TGAACTGGAACTCTCTGTGCGCCAATTAACTCGTATTGAAGCAGGTACTTCCAAGCCGACTTTTTCAAAGATTCAGTATA
TTGCAACTCGTTTAGGTATGGGACTTTACGAGCTTATGCCAGATTACGTATCCTTACCCGAAAGATATTCCAAGCTGAAG
TTTGATGTGCTTCGCACCCCAACTTATGGTAATGAAGATTTGGCGGAAAAGCGAGATGCCATGATGACAGAAATCTATGA
CGATTATTATGATGAATTGCCTGAGGAGGAGAAGATAGCAATAGATGCGATTCAATCACGAATTGATACTTTAGAGTCAG
GTACAGCAGGCTTTGGAAAAGAGATACTGGAAGACTACTTTGAACAAATTTTTCGCAAACGAAAGTATGAATTGAATGAT
TTGTTGATTGTTAGGCTCCATCTTGAATATGTTAGGTTATCTAGCTGTGATTCAGAAATATTTAGACAGTTTTTGAAAAT
TATAGAGCATTTACATGAGCAAATCAATATCATCAACTCAAATGATTTATTTGTTCTAAGGGATACATTATTATCCTGTG
TAAACATTTTGGGAAGTAAAAAATATTACGAACCAATACCAAAGATATTTGATAGTGTAGATAAGATTATACAGTCGACA
CAAGATTTTCAGAAAAAGCCCATTGTTAGTGTATTAAAATGGAAATATGCACTTTTTGTGGATAAGGATCGGGATGAGGC
TGAAAAGCATTATCTAGATGCGGTGCTATTTGCAAAATTGATAGAAAATAGAGAGTTAGAACAAAAGATTGAAGAAGATT
GGAGAGTTGACAATCAATAA

Domains

Predicted by InterProScan.

Helix-turn-helix domain (HTH_31)

(5-60)

ComR tetratricopeptide (ComR_TPR)

(73-294)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

99.666

100

0.997
  comR Streptococcus suis 05ZYH33

99.666

100

0.997
  comR Streptococcus suis D9

61.794

100

0.622
  comR Streptococcus mutans UA159

43.813

100

0.438
  comR Streptococcus pyogenes MGAS315

37.374

99.331

0.371