Detailed information NTG0799725

Bioinformatically predicted

Overview

• Name: pknB
• Type: Regulator
• Locus tag: P1I87_RS02480
• Genome accession: NZ_CP119576
• Coordinates: 443753..445708 (+)
• Length: 651 a.a.
• NCBI ID: WP_161512424.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain Guangzhou-SAG092
• Function: modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology) Competence regulation

Genomic Context

Location: 438753..450708

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P1I87_RS02465 (P1I87_02465)	fmt	440731..441666 (+)	936	WP_000163893.1	methionyl-tRNA formyltransferase	-
P1I87_RS02470 (P1I87_02470)	rsmB	441656..442978 (+)	1323	WP_001262599.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
P1I87_RS02475 (P1I87_02475)	-	443016..443753 (+)	738	WP_000406233.1	Stp1/IreP family PP2C-type Ser/Thr phosphatase	-
P1I87_RS02480 (P1I87_02480)	pknB	443753..445708 (+)	1956	WP_161512424.1	Stk1 family PASTA domain-containing Ser/Thr kinase	Regulator
P1I87_RS02485 (P1I87_02485)	liaF	445869..446564 (+)	696	WP_000714456.1	cell wall-active antibiotics response protein LiaF	-
P1I87_RS02490 (P1I87_02490)	-	446561..447580 (+)	1020	WP_000716170.1	sensor histidine kinase	-
P1I87_RS02495 (P1I87_02495)	-	447573..448214 (+)	642	WP_000357892.1	response regulator transcription factor	-
P1I87_RS02500 (P1I87_02500)	-	448256..449656 (+)	1401	WP_000339133.1	bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase	-
P1I87_RS02505 (P1I87_02505)	-	449658..450014 (+)	357	WP_000689608.1	S1 RNA-binding domain-containing protein	-

Sequence

Protein

• Length: 651 a.a.
• Molecular weight: 70771.51 Da
• Isoelectric Point: 9.6759

>NTDB_id=799725 P1I87_RS02480 WP_161512424.1 443753..445708(+) (pknB) [Streptococcus agalactiae strain Guangzhou-SAG092]
MIQIGKLFAGRYRILKSIGRGGMADVYLARDLILDNEEVAIKVLRTNYQTDQIAVARFQREARAMAELTHPNIVAIRDIG
EEDGQQFLVMEYVDGFDLKKYIQDNAPLSNNEVVRIMNEVLSAMSLAHQKGIVHRDLKPQNILLTKKGTVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSILAENKSVP
QALENIVIKATAKKLTDRYKTTYEMGRDLSTALSSTRHREPKLVFNDTESTKTLPKVTSTVSSLTTEQLLRNQKQAKTTE
KITPDSASNDKTKSKKKASHRLLGTIMKLFFALCVVGIIVFAYKILVSPTTIRVPDVSNKTVAQAKMTLENSGLKVGAIR
NIESDSVSEGLVVKTDPAAGRSRREGAKVNLYIATPNKSFTLGNYKEHNYKDILKDLQGKGVKKSLIKVKRKINNDYTTG
TILAQSLPEGTSFNPDGNKKLTLTVAVNDPMIMPDVTGMTVGEVIETLTDLGLDADNLVFYQMQNGVYQTVATPPSSSKI
ASQDPYYGGEVGLRRGDKVKLYLLGSKTTNNSSSTPIDSSASSSTGTTTSDSVSSSTDASTSDSSSTSTSSSTLPSDSTT
NTGTANNPLTQ

Nucleotide

• Length: 1956 bp

>NTDB_id=799725 P1I87_RS02480 WP_161512424.1 443753..445708(+) (pknB) [Streptococcus agalactiae strain Guangzhou-SAG092]
ATGATTCAGATTGGCAAATTATTTGCTGGTCGTTATCGGATCCTTAAATCAATCGGACGAGGTGGAATGGCGGATGTTTA
TCTAGCTCGAGATCTAATTTTAGATAATGAAGAGGTCGCAATAAAAGTATTGCGAACCAATTATCAAACAGATCAGATTG
CGGTTGCTCGCTTCCAGAGAGAAGCACGAGCAATGGCTGAGCTGACACATCCTAATATTGTCGCTATTCGTGATATAGGT
GAAGAAGACGGACAGCAGTTCTTAGTAATGGAATATGTTGATGGATTCGATTTAAAAAAGTATATTCAAGACAATGCACC
CCTATCAAATAATGAAGTTGTTCGAATCATGAATGAAGTCCTTTCAGCCATGTCACTGGCACATCAGAAAGGTATCGTAC
ACCGTGATTTAAAACCTCAAAATATTTTATTAACTAAAAAAGGGACTGTAAAAGTTACAGATTTCGGTATTGCGGTAGCG
TTTGCTGAAACTAGTTTAACGCAAACGAATTCTATGTTAGGTAGTGTTCATTATTTATCGCCAGAGCAGGCGCGTGGTTC
AAAAGCGACTGTTCAGAGTGATATTTATGCCATGGGAATCATGCTTTTTGAAATGTTAACTGGCCATATTCCTTATGATG
GGGATAGTGCAGTTACTATTGCCCTACAGCACTTCCAAAAACCACTACCATCAATCCTTGCAGAAAATAAAAGCGTTCCA
CAAGCTTTGGAAAACATTGTCATTAAAGCAACAGCTAAAAAGCTAACAGATCGCTATAAGACAACTTATGAGATGGGACG
TGATTTATCAACTGCTCTAAGCTCGACACGTCACCGTGAACCAAAACTTGTTTTTAATGATACTGAGAGTACTAAGACAC
TACCCAAAGTAACATCTACAGTATCATCTCTAACGACAGAACAACTGTTGCGTAATCAAAAACAGGCCAAAACAACAGAA
AAAATAACTCCTGATTCTGCGAGTAACGATAAAACGAAGTCTAAAAAGAAGGCTTCTCATCGACTTCTTGGTACAATCAT
GAAATTATTCTTTGCACTCTGTGTTGTAGGAATAATTGTATTTGCTTATAAAATTTTAGTAAGTCCTACGACTATTCGTG
TTCCAGATGTTAGCAACAAAACAGTAGCTCAAGCAAAAATGACATTGGAAAATTCTGGATTGAAAGTAGGAGCTATTCGT
AATATTGAGAGTGATAGTGTTTCAGAAGGACTTGTCGTAAAAACAGACCCTGCTGCAGGACGTTCTCGCAGAGAAGGGGC
TAAAGTTAATCTTTATATTGCCACTCCAAACAAGAGTTTCACTCTAGGTAATTATAAGGAACATAATTACAAAGATATCC
TCAAAGATCTTCAAGGCAAAGGTGTTAAAAAATCTTTAATCAAGGTTAAGCGTAAAATTAATAATGATTATACTACTGGT
ACAATCTTAGCACAGTCGCTTCCAGAAGGAACATCTTTTAATCCTGATGGTAATAAGAAATTAACACTTACGGTTGCTGT
TAATGATCCAATGATTATGCCTGATGTAACAGGTATGACTGTTGGAGAAGTAATAGAAACCTTGACAGACCTCGGATTAG
ATGCAGATAATCTTGTCTTCTATCAAATGCAAAACGGCGTTTATCAAACAGTAGCAACACCTCCATCTTCAAGTAAGATA
GCAAGTCAGGATCCTTATTACGGAGGAGAAGTTGGATTAAGGAGAGGAGATAAAGTTAAGCTGTATCTTCTTGGTTCTAA
AACAACGAATAACTCATCATCTACGCCAATAGATTCTTCGGCTTCAAGCTCAACAGGAACAACTACCTCGGATTCTGTAA
GCTCATCAACGGATGCTAGCACTTCTGATAGTAGTAGCACTTCTACAAGTAGTTCAACACTACCAAGTGATAGTACAACT
AATACAGGAACAGCTAACAATCCATTAACTCAATAA

Domains

Predicted by InterproScan.

• PASTA domain (PASTA) (511-583)

• PASTA domain (PASTA) (373-434)

• PASTA domain (PASTA) (441-506)

• Protein kinase domain (Pkinase) (12-254)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pknB	Streptococcus mutans UA159	60.959	89.708	0.547
stkP/pknB	Streptococcus salivarius strain HSISS4	61.073	88.786	0.542
stkP	Streptococcus pneumoniae TIGR4	59.612	79.109	0.472
stkP	Streptococcus pneumoniae D39	59.417	79.109	0.47
stkP	Streptococcus pneumoniae R6	59.417	79.109	0.47
stkP	Streptococcus pneumoniae Rx1	59.223	79.109	0.469