Detailed information NTG0799644

Bioinformatically predicted

Overview

• Name: comGB
• Type: Machinery gene
• Locus tag: RDV59_RS00310
• Genome accession: NZ_CP133476
• Coordinates: 50532..51632 (-)
• Length: 366 a.a.
• NCBI ID: WP_126405090.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain LMG 11489
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 45532..56632

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RDV59_RS00270 (RDV59_00270)	-	46141..46338 (-)	198	WP_002885716.1	helix-turn-helix transcriptional regulator	-
RDV59_RS00275 (RDV59_00275)	-	46589..47782 (-)	1194	WP_002885831.1	acetate kinase	-
RDV59_RS00280 (RDV59_00280)	comGH	47839..48795 (-)	957	WP_038676858.1	class I SAM-dependent methyltransferase	Machinery gene
RDV59_RS00285 (RDV59_00285)	comGG	48840..49157 (-)	318	WP_002887013.1	competence type IV pilus minor pilin ComGG	Machinery gene
RDV59_RS00290 (RDV59_00290)	comGF	49135..49572 (-)	438	WP_002887014.1	competence type IV pilus minor pilin ComGF	Machinery gene
RDV59_RS00295 (RDV59_00295)	comGE	49559..49789 (-)	231	WP_002887015.1	competence type IV pilus minor pilin ComGE	Machinery gene
RDV59_RS00300 (RDV59_00300)	comGD	49821..50249 (-)	429	WP_254593949.1	competence type IV pilus minor pilin ComGD	Machinery gene
RDV59_RS00305 (RDV59_00305)	comGC	50209..50523 (-)	315	WP_170314557.1	competence type IV pilus major pilin ComGC	Machinery gene
RDV59_RS00310 (RDV59_00310)	comGB	50532..51632 (-)	1101	WP_126405090.1	competence type IV pilus assembly protein ComGB	Machinery gene
RDV59_RS00315 (RDV59_00315)	comGA/cglA/cilD	51514..52455 (-)	942	WP_038676863.1	competence type IV pilus ATPase ComGA	Machinery gene
RDV59_RS00320 (RDV59_00320)	-	52535..52897 (-)	363	WP_002887019.1	DUF1033 family protein	-

Sequence

Protein

• Length: 366 a.a.
• Molecular weight: 41608.71 Da
• Isoelectric Point: 10.1478

>NTDB_id=799644 RDV59_RS00310 WP_126405090.1 50532..51632(-) (comGB) [Streptococcus salivarius strain LMG 11489]
MPVKISKAIRQSAGTSSWKAWLNKDISLKGISKGKKLKINQQLKVIQLFKQLLKAGFTLTEIVAFLERSHLLKESSLSLM
KTSLMRGDRLDQMFAAVGFSDNIVTQIALADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKENWAVQLVQIFPQLFFATLCGLLVLSLILYLWVKRQPALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGIDLLDLVALMKEQKSKLFRELGADLEEALMLGQSFPDRIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QAFFNRLNKATTFVQPLIFVIVAVVIVMIYAAMLLPMYQNMEGMMS

Nucleotide

• Length: 1101 bp

>NTDB_id=799644 RDV59_RS00310 WP_126405090.1 50532..51632(-) (comGB) [Streptococcus salivarius strain LMG 11489]
TTGCCAGTGAAAATTTCCAAAGCCATTCGTCAATCAGCTGGAACCAGCAGTTGGAAGGCTTGGTTAAACAAGGATATCTC
ACTGAAGGGGATATCCAAGGGGAAAAAATTAAAGATTAATCAGCAACTCAAGGTTATCCAGCTTTTCAAACAACTTTTAA
AGGCAGGGTTTACCTTGACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGTTAAAAGAATCGTCCTTGTCTCTTATG
AAAACGAGTTTAATGCGAGGCGATAGGTTGGACCAGATGTTTGCGGCAGTGGGCTTTTCGGACAATATTGTTACTCAGAT
TGCCCTTGCTGATAAGCACGGTAACCTTCTAGGGAGTTTAACCAAGATTGAAACCTATATGCTTCGTATGACCAAGGTTC
GTAAGAAACTCATGGAGGTAGCGACCTACCCTATTCTACTTCTGGGTTTCCTGATTCTGATTATGTTGGGGCTCAAAAAT
TATCTTTTACCTCAACTGTTAGAGGGGGATGGTAAGGAGAATTGGGCTGTACAGTTGGTTCAGATTTTTCCCCAGCTCTT
TTTTGCGACTTTGTGCGGACTTCTTGTATTAAGCTTAATTCTCTACCTATGGGTCAAACGCCAGCCAGCTCTTGTCTTTT
ATCGACGAATGGCAAAAATCCCTTTTATAGGGCAAACTGTCAGGCTATATACGACTGCCTATTATGCTAGGGAATGGGGA
AATCTCTTAGGGCAAGGTATTGACTTGCTAGACTTAGTTGCTCTAATGAAAGAGCAAAAGTCCAAGCTTTTTCGTGAGCT
GGGGGCTGATTTAGAAGAAGCCTTGATGCTAGGACAGAGTTTTCCTGACCGTATTGCTAGTCACCCTTTCTTCACTAAGG
AACTATCCTTAATTATTGCTTATGGAGAGGCTAATGCTAGGTTGGGCTATGAGTTAGAAGTCTATGCTGAAGAGGTTTGG
CAGGCTTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCTGTCGTGATTGT
AATGATCTATGCAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterProScan.

• Type II secretion system (T2SS), protein F (T2SSF) (51-164)

• Type II secretion system (T2SS), protein F (T2SSF) (236-356)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGB	Streptococcus mutans UA140	54.81	93.716	0.514
comGB	Streptococcus mutans UA159	54.81	93.716	0.514
comGB	Streptococcus gordonii str. Challis substr. CH1	51.312	93.716	0.481
comGB/cglB	Streptococcus mitis NCTC 12261	49.558	92.623	0.459
comGB/cglB	Streptococcus mitis SK321	49.408	92.35	0.456
comGB/cglB	Streptococcus pneumoniae Rx1	48.817	92.35	0.451
comGB/cglB	Streptococcus pneumoniae D39	48.817	92.35	0.451
comGB/cglB	Streptococcus pneumoniae R6	48.817	92.35	0.451
comGB/cglB	Streptococcus pneumoniae TIGR4	48.817	92.35	0.451
comGB	Lactococcus lactis subsp. cremoris KW2	44.377	89.891	0.399