Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   P0G38_RS12475 Genome accession   NZ_CP119393
Coordinates   2598130..2599434 (+) Length   434 a.a.
NCBI ID   WP_010747716.1    Uniprot ID   A0A242C4H0
Organism   Enterococcus casseliflavus strain ASE4     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2593130..2604434
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P0G38_RS12455 (P0G38_12455) - 2593731..2595251 (-) 1521 WP_275851529.1 C40 family peptidase -
  P0G38_RS12460 (P0G38_12460) map 2595673..2596431 (-) 759 WP_005234612.1 type I methionyl aminopeptidase -
  P0G38_RS12465 (P0G38_12465) truA 2596474..2597211 (-) 738 WP_005225435.1 tRNA pseudouridine(38-40) synthase TruA -
  P0G38_RS12470 (P0G38_12470) rlmH 2597277..2597756 (-) 480 WP_275851540.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  P0G38_RS12475 (P0G38_12475) htrA 2598130..2599434 (+) 1305 WP_010747716.1 S1C family serine protease Regulator
  P0G38_RS12480 (P0G38_12480) ytpR 2599503..2600117 (-) 615 WP_005225431.1 YtpR family tRNA-binding protein -
  P0G38_RS12485 (P0G38_12485) - 2600697..2601158 (-) 462 WP_005225429.1 universal stress protein -
  P0G38_RS12490 (P0G38_12490) - 2601171..2601491 (-) 321 WP_275851549.1 thioredoxin family protein -
  P0G38_RS12495 (P0G38_12495) pepA 2601625..2602701 (-) 1077 WP_034872382.1 glutamyl aminopeptidase -
  P0G38_RS12500 (P0G38_12500) - 2602994..2603338 (+) 345 WP_005225425.1 peptidase -
  P0G38_RS12505 (P0G38_12505) - 2603399..2604433 (-) 1035 WP_275851554.1 hypothetical protein -

Sequence

Protein


Download         Length: 434 a.a.        Molecular weight: 44836.30 Da        Isoelectric Point: 4.0084

>NTDB_id=798827 P0G38_RS12475 WP_010747716.1 2598130..2599434(+) (htrA) [Enterococcus casseliflavus strain ASE4]
MARKYVTPGKKTSPGLLKRLGIGILGGMVGGLLTFGGLYLAMGSSLTSTPETTTNSGVQDSNGQTQVSNVKLDVTSDVTE
AVEKVQDSVVSIINLQQSQSNDWNSLFGQQGGQSEGDSQSDDDSALEASSEGSGVIYKIDGDDAYVVTNNHVVEGQDGLE
VVLADGTKVKAELVGTDAYTDLAVLKISSEHVTTAATFGDSSALKVGEPAIAIGSPLGSDYANSVTQGIVSSLNRQVTSQ
NESGGTISINAIQTDAAINPGNSGGPLINVDGQVIGINSSKIASTSGSASGVSVEGMGFAIPSNDVVEIINQLEADGKVV
RPALGIQTIDLGSITSQQQEQILKVPSSVTSGVVIYSVNNATPAEQAGLQQYDVITKIDDTEVSTTTDLQSALYKHKVGD
TITVTFYRGDEEKTAEVKLSVDTSINEQSTDSSN

Nucleotide


Download         Length: 1305 bp        

>NTDB_id=798827 P0G38_RS12475 WP_010747716.1 2598130..2599434(+) (htrA) [Enterococcus casseliflavus strain ASE4]
ATGGCAAGAAAATATGTCACACCAGGCAAGAAAACTTCTCCTGGTTTATTAAAACGATTAGGTATTGGGATTTTAGGCGG
TATGGTCGGCGGTTTATTGACCTTCGGCGGTCTGTATCTGGCAATGGGTTCCTCTTTGACTTCAACACCAGAAACCACGA
CCAACAGCGGGGTCCAAGATTCTAACGGACAAACCCAAGTATCCAATGTAAAACTTGATGTGACTAGCGATGTCACTGAG
GCAGTTGAAAAAGTACAAGATTCTGTCGTTTCCATCATTAATCTACAACAAAGTCAAAGCAACGATTGGAACAGCCTTTT
TGGTCAGCAAGGCGGACAAAGTGAAGGCGATAGCCAAAGCGACGACGACAGTGCTTTAGAAGCTTCTTCTGAAGGGAGTG
GGGTCATCTACAAAATCGATGGCGACGATGCCTATGTTGTAACCAACAACCACGTCGTAGAAGGTCAAGACGGTTTAGAA
GTTGTTTTAGCAGACGGTACGAAAGTCAAAGCTGAATTGGTCGGTACTGACGCTTACACAGACTTAGCTGTATTGAAAAT
CTCTTCAGAGCATGTGACGACTGCCGCAACATTTGGTGATTCAAGTGCCTTGAAAGTCGGCGAACCAGCCATCGCGATCG
GTTCTCCTCTAGGCTCTGACTACGCAAACTCTGTGACACAAGGGATCGTTTCTTCCTTGAATCGTCAAGTAACAAGCCAA
AACGAATCTGGTGGTACGATCAGCATCAATGCGATTCAAACGGATGCTGCGATCAACCCAGGGAACTCAGGTGGTCCACT
GATCAACGTTGATGGCCAAGTGATTGGGATCAACTCAAGTAAAATCGCCAGCACCTCTGGCTCTGCTTCAGGTGTTAGTG
TCGAAGGGATGGGCTTTGCGATCCCAAGTAACGATGTCGTTGAAATCATCAATCAACTAGAAGCAGACGGCAAAGTGGTC
CGCCCTGCACTAGGGATCCAAACGATCGATTTAGGTTCCATCACATCACAACAACAAGAACAAATCTTGAAAGTTCCTTC
ATCCGTAACTTCAGGCGTTGTGATCTACTCAGTCAACAATGCAACACCAGCAGAACAAGCAGGATTGCAACAATATGACG
TTATCACGAAGATCGATGATACAGAAGTCAGCACAACAACGGATCTGCAATCTGCGTTGTACAAACACAAAGTCGGTGAC
ACGATCACTGTAACCTTCTATCGTGGCGATGAAGAAAAAACAGCAGAAGTAAAACTTTCCGTTGATACGTCGATCAACGA
ACAATCAACAGACAGCAGCAACTAA

Domains

Predicted by InterproScan.

Peptidase family M50 (Peptidase_M50)

(19-420)

Trypsin-like peptidase domain (Trypsin_2)

(132-277)

PDZ domain (PDZ_2)

(322-419)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A242C4H0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

56.423

91.475

0.516
  htrA Streptococcus gordonii str. Challis substr. CH1

50.835

96.544

0.491
  htrA Streptococcus mitis NCTC 12261

55.71

82.719

0.461
  htrA Streptococcus pneumoniae TIGR4

57.31

78.802

0.452
  htrA Streptococcus pneumoniae D39

57.31

78.802

0.452
  htrA Streptococcus pneumoniae Rx1

57.31

78.802

0.452
  htrA Streptococcus pneumoniae R6

57.31

78.802

0.452