Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   PY824_RS11540 Genome accession   NZ_CP119172
Coordinates   2208130..2209362 (+) Length   410 a.a.
NCBI ID   WP_307777631.1    Uniprot ID   -
Organism   Streptococcus macedonicus strain SGM CIP105683     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2203130..2214362
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PY824_RS11510 (PY824_11510) - 2203168..2203467 (+) 300 Protein_2209 mercuric transporter MerT family protein -
  PY824_RS11515 (PY824_11515) - 2203471..2203626 (+) 156 WP_002360746.1 hypothetical protein -
  PY824_RS11695 - 2203642..2203794 (+) 153 Protein_2211 heavy metal-associated domain-containing protein -
  PY824_RS11520 (PY824_11520) merA 2203827..2205467 (+) 1641 WP_093529447.1 mercury(II) reductase -
  PY824_RS11525 (PY824_11525) - 2205709..2207031 (+) 1323 WP_039671354.1 ISL3 family transposase -
  PY824_RS11535 (PY824_11535) rlmH 2207407..2207886 (-) 480 WP_014295514.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  PY824_RS11540 (PY824_11540) htrA 2208130..2209362 (+) 1233 WP_307777631.1 trypsin-like peptidase domain-containing protein Regulator
  PY824_RS11545 (PY824_11545) spo0J 2209432..2210208 (+) 777 WP_058621987.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 42575.08 Da        Isoelectric Point: 4.0556

>NTDB_id=798075 PY824_RS11540 WP_307777631.1 2208130..2209362(+) (htrA) [Streptococcus macedonicus strain SGM CIP105683]
MPKFNYKNWLKPLGVILVGFIAGVAGTILVLNMAGISITNVGGSSTKTTTSSVSYSNSNDTTKAVEKVQDAVVSVINYKS
DSSSSTSDLYNQFFGNDSDSSSDSSSTDDLTVYSEGSGVIYKKDGDSAYVVTNNHVIDGAEQIEIMLADGTKVVGELVGA
DTYSDIAVVKISSDNVSTVAEFADSDKLTVGETAIAIGSPLGTEYANSVTQGIVSSLSRTVTMTNDDGKTISTNAIQTDA
AINPGNSGGALINIEGQVIGINSSKISSTSSSGEFVEGMGFAIPSNDVVSIINQLEENGQVIRPALGISMVNLSDLSTNA
IAQLNIPTSVTSGVVVAAVQSGMPAEGNLEQYDVITAIDDKEVTSTSDLQSILYTHSVGDSVKVTFYRGTDKKTATIKLT
KTTQDLSSSN

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=798075 PY824_RS11540 WP_307777631.1 2208130..2209362(+) (htrA) [Streptococcus macedonicus strain SGM CIP105683]
TTGCCAAAATTTAATTACAAAAATTGGTTAAAACCATTGGGTGTCATTTTAGTCGGCTTTATAGCTGGTGTCGCAGGTAC
AATACTCGTCCTAAATATGGCAGGTATTTCAATCACTAACGTCGGTGGTTCAAGTACAAAAACAACAACAAGTAGCGTAA
GCTATTCTAACTCTAACGATACAACAAAAGCTGTGGAAAAAGTTCAAGACGCAGTTGTATCTGTTATTAACTACAAATCA
GACTCGTCGTCTTCTACAAGTGACCTCTACAATCAATTCTTTGGCAATGATTCAGACAGTAGTAGCGATTCAAGCTCTAC
AGATGATTTGACTGTTTACAGTGAAGGTTCTGGGGTTATTTACAAAAAAGATGGTGATTCTGCTTATGTCGTCACTAACA
ATCACGTTATTGATGGGGCTGAACAAATTGAAATCATGCTTGCTGATGGAACAAAAGTTGTTGGTGAGCTAGTCGGAGCA
GATACTTATTCAGATATTGCCGTTGTCAAAATTTCTTCTGACAACGTATCTACAGTTGCTGAATTTGCCGATTCTGATAA
ATTAACTGTCGGTGAAACTGCTATCGCTATTGGTAGCCCACTCGGTACTGAATATGCTAACTCTGTAACACAAGGTATTG
TCTCAAGTCTTAGCCGTACAGTAACCATGACAAATGATGATGGTAAAACTATCTCAACAAATGCTATCCAAACGGATGCA
GCGATTAACCCAGGTAACTCTGGTGGTGCTTTAATTAACATTGAAGGACAAGTTATCGGTATCAATTCAAGTAAGATTTC
ATCTACATCAAGTTCTGGTGAATTTGTCGAAGGTATGGGATTTGCCATTCCATCTAACGATGTTGTATCCATTATTAACC
AATTGGAAGAAAATGGGCAAGTTATCCGCCCAGCACTTGGTATTTCAATGGTAAACTTGAGCGACCTTTCAACAAATGCA
ATTGCTCAACTTAACATTCCAACAAGTGTAACAAGCGGTGTCGTTGTGGCGGCTGTTCAATCTGGTATGCCAGCTGAAGG
TAATCTCGAACAATATGATGTCATCACAGCTATTGACGACAAAGAAGTAACATCTACTTCAGATCTTCAAAGTATCCTTT
ATACTCATTCTGTTGGTGACTCTGTCAAAGTAACCTTCTACCGTGGAACTGATAAGAAAACAGCCACAATTAAATTAACT
AAGACAACACAAGATTTATCTTCCTCAAACTGA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(116-261)

PDZ domain (PDZ_2)

(304-399)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

64.691

98.78

0.639
  htrA Streptococcus gordonii str. Challis substr. CH1

60.049

99.512

0.598
  htrA Streptococcus pneumoniae D39

58.809

98.293

0.578
  htrA Streptococcus pneumoniae TIGR4

58.809

98.293

0.578
  htrA Streptococcus pneumoniae R6

58.809

98.293

0.578
  htrA Streptococcus pneumoniae Rx1

58.809

98.293

0.578
  htrA Streptococcus mitis NCTC 12261

58.561

98.293

0.576