Detailed information NTG0798044

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: PY824_RS03380
• Genome accession: NZ_CP119172
• Coordinates: 604364..606595 (+)
• Length: 743 a.a.
• NCBI ID: WP_115266023.1
• Uniprot ID: -
• Organism: Streptococcus macedonicus strain SGM CIP105683
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 599364..611595

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PY824_RS03355 (PY824_03355)	-	600126..601706 (+)	1581	WP_014294203.1	DEAD/DEAH box helicase	-
PY824_RS03360 (PY824_03360)	-	601749..602021 (-)	273	WP_014294204.1	GIY-YIG nuclease family protein	-
PY824_RS03365 (PY824_03365)	-	601996..602757 (-)	762	WP_115266022.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
PY824_RS03370 (PY824_03370)	-	602865..603611 (+)	747	WP_014294206.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
PY824_RS03375 (PY824_03375)	comEA	603706..604371 (+)	666	WP_039670586.1	helix-hairpin-helix domain-containing protein	Machinery gene
PY824_RS03380 (PY824_03380)	comEC/celB	604364..606595 (+)	2232	WP_115266023.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
PY824_RS03385 (PY824_03385)	holA	606667..607704 (+)	1038	WP_039670612.1	DNA polymerase III subunit delta	-
PY824_RS03390 (PY824_03390)	sodA	607793..608401 (+)	609	WP_014294210.1	superoxide dismutase SodA	-
PY824_RS03395 (PY824_03395)	-	608552..609277 (+)	726	WP_014294211.1	YebC/PmpR family DNA-binding transcriptional regulator	-
PY824_RS03400 (PY824_03400)	queA	609309..610337 (-)	1029	WP_039670588.1	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	-
PY824_RS03405 (PY824_03405)	-	610554..611012 (+)	459	WP_223246245.1	VIT1/CCC1 transporter family protein	-

Sequence

Protein

• Length: 743 a.a.
• Molecular weight: 84058.61 Da
• Isoelectric Point: 8.8509

>NTDB_id=798044 PY824_RS03380 WP_115266023.1 604364..606595(+) (comEC/celB) [Streptococcus macedonicus strain SGM CIP105683]
MIKYFPIKPIQLAFLLILLYYFCFSKVIGCLMFLLLVLVFLWQQYGWKAWCQVCLCLSCFAVFFLTKSNQTEQAYQVVPA
HLTKIQMIPDTISVNGDLLSFRGKEAGRTYQIFYTLKSEKEQHFFKTLNQTIVLSGDMDLEEATPQRNFGGFDYRTYLKH
EGIYRVVNLSAINNVELVYKMTLWDKLHDVRRKAIVSIQRHFPAPMQHYMTGLLFGYLDKSFDEMSDVYTSLGIIHLFAL
SGMQVGFFVGTFRFFFLRLGLRRDYVDILQIPFSLVYAGLTGYSVSVIRSLIQSAFANLGIKKLDNLALTLFVLFMVMPN
FLLTTGGILSFTYAFILSFIDFNDISRYQKIIAESLTISLASLPLLIHFFAVFQPLSILLTAIFSVAFDTIMLPMLSIIF
ILSPLVKLTCFNGCFVFLETVIKNTKVILGGPIVFGKPSLGILVLLFLTLGVLYDCWRRKKMAIFLVSLVVLLFFQIKHP
LENEVTVVDIGQGDSIFVRDVKGHTLLIDVGGKVSFSEKNAWQERLTDSNAERTLIPYLNSRGVGKIDQLVLTHTDTDHM
GDMLEVAKHVKIGKVLVSQGSLTKPDFVAKLQAMKTKVRVVTASDVLPIMGSYLQVLYPSQTGDGGNNDSVVLYGNLLGK
NFLFTGDLEEEGEQELVATYPNLPVDVLKAGHHGSKGSSSSEFLAHISPQIALISAGQNNRYKHPHQETLERFRAQNMTI
YRTDEQGAIRFRGLNHWKIETVR

Nucleotide

• Length: 2232 bp

>NTDB_id=798044 PY824_RS03380 WP_115266023.1 604364..606595(+) (comEC/celB) [Streptococcus macedonicus strain SGM CIP105683]
TTGATTAAGTATTTTCCCATTAAGCCAATTCAATTGGCTTTTTTGCTCATTTTGCTCTATTATTTTTGCTTTTCAAAAGT
GATTGGGTGTTTGATGTTTCTCTTGCTAGTCTTGGTGTTTTTATGGCAACAGTATGGTTGGAAGGCTTGGTGTCAAGTTT
GTTTGTGTTTAAGCTGTTTTGCGGTATTTTTTCTGACTAAGTCTAATCAGACAGAGCAGGCTTATCAAGTAGTGCCAGCT
CATTTAACAAAAATCCAGATGATTCCTGACACGATTTCGGTCAATGGAGATTTGCTGTCCTTTCGAGGTAAGGAAGCTGG
GCGGACTTATCAGATTTTTTATACCTTGAAATCGGAGAAAGAACAGCATTTTTTTAAGACATTAAATCAAACGATTGTTT
TATCTGGTGATATGGACTTGGAAGAAGCAACGCCCCAGCGGAATTTTGGTGGTTTTGATTATCGTACTTACCTTAAACAT
GAAGGCATTTATCGTGTGGTAAATTTGTCGGCGATTAACAATGTTGAACTTGTTTATAAGATGACTTTGTGGGATAAGCT
ACATGATGTTCGACGAAAGGCTATTGTTAGTATTCAGCGGCATTTTCCTGCTCCTATGCAACATTATATGACTGGGCTTT
TGTTTGGCTATCTGGATAAATCGTTTGATGAGATGAGTGATGTTTACACGAGTTTAGGAATTATTCACCTCTTTGCTCTT
TCAGGTATGCAGGTCGGATTTTTTGTGGGGACATTCCGATTTTTCTTTCTACGTCTTGGGTTACGCCGAGATTATGTGGA
TATACTACAAATCCCATTTTCACTCGTCTATGCGGGGCTGACTGGCTATTCTGTTTCGGTGATTCGGAGTTTAATTCAAT
CTGCTTTTGCAAATCTTGGTATTAAAAAATTAGATAACTTGGCTTTAACTTTGTTTGTTCTTTTCATGGTTATGCCAAAT
TTTTTACTGACGACGGGAGGCATTCTTTCGTTTACTTACGCTTTTATTCTCAGTTTTATTGACTTTAATGACATTAGTCG
CTATCAGAAAATCATTGCGGAAAGTTTGACGATTTCATTAGCCAGTTTGCCCTTGTTAATTCATTTTTTTGCTGTGTTTC
AACCGTTATCTATCTTATTGACAGCAATTTTTTCTGTGGCATTTGACACTATTATGTTGCCAATGTTATCAATCATTTTT
ATTTTATCGCCCTTGGTTAAACTGACTTGTTTTAATGGTTGTTTTGTTTTTTTGGAAACTGTTATCAAGAACACTAAGGT
AATTTTGGGCGGTCCGATTGTTTTTGGGAAACCAAGTCTTGGTATCTTGGTGCTACTATTTTTAACATTAGGCGTGCTTT
ATGATTGCTGGCGACGAAAGAAAATGGCAATTTTTCTTGTCAGCTTAGTAGTTCTGCTATTTTTTCAAATCAAGCATCCG
CTAGAAAACGAGGTGACAGTGGTTGATATTGGGCAGGGAGATAGTATTTTTGTGCGTGATGTTAAGGGGCATACGCTGCT
AATTGATGTGGGTGGAAAGGTGAGTTTTAGTGAGAAGAACGCGTGGCAGGAGCGGCTGACGGATAGTAATGCGGAGCGAA
CGTTGATTCCTTATCTCAACAGTCGCGGCGTTGGAAAAATTGACCAGTTAGTTCTGACGCACACGGATACTGACCACATG
GGAGATATGCTGGAGGTGGCGAAACACGTAAAAATTGGTAAAGTGCTGGTGAGTCAGGGAAGTTTGACAAAGCCAGATTT
TGTGGCGAAATTACAAGCCATGAAAACCAAGGTGCGCGTGGTAACAGCTAGTGATGTTTTGCCGATTATGGGAAGTTACC
TGCAAGTGCTTTATCCGAGCCAGACTGGTGATGGTGGTAACAATGACTCGGTGGTGCTTTATGGGAATCTTTTGGGTAAG
AATTTCTTATTTACAGGAGATTTGGAAGAAGAAGGCGAGCAAGAGTTGGTTGCAACTTATCCCAATCTGCCGGTTGATGT
CTTAAAAGCAGGGCATCATGGCTCAAAAGGGTCATCAAGCTCAGAATTTCTCGCTCACATTTCACCGCAAATTGCTTTAA
TTTCCGCAGGGCAAAATAACCGCTACAAACATCCTCATCAAGAGACACTTGAACGCTTCCGAGCACAAAACATGACCATT
TACCGCACAGACGAACAAGGCGCTATCCGCTTTAGAGGATTAAACCACTGGAAAATCGAAACAGTGAGGTAG

Domains

Predicted by InterproScan.

• Competence protein (Competence) (213-459)

• Metallo-beta-lactamase superfamily (Lactamase_B) (491-697)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	52.156	99.865	0.521
comEC/celB	Streptococcus mitis SK321	51.617	99.865	0.515
comEC/celB	Streptococcus pneumoniae TIGR4	50.606	100	0.506
comEC/celB	Streptococcus pneumoniae Rx1	50.067	100	0.501
comEC/celB	Streptococcus pneumoniae D39	50.067	100	0.501
comEC/celB	Streptococcus pneumoniae R6	50.067	100	0.501
comEC	Lactococcus lactis subsp. cremoris KW2	47.849	100	0.479