Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   PY824_RS01935 Genome accession   NZ_CP119172
Coordinates   335506..336261 (+) Length   251 a.a.
NCBI ID   WP_093527953.1    Uniprot ID   -
Organism   Streptococcus macedonicus strain SGM CIP105683     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 330506..341261
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PY824_RS01920 (PY824_01920) - 330914..332485 (-) 1572 WP_014293964.1 ABC transporter permease subunit -
  PY824_RS01925 (PY824_01925) - 332619..334514 (+) 1896 WP_051673263.1 DUF2207 domain-containing protein -
  PY824_RS01930 (PY824_01930) - 334566..335405 (+) 840 WP_014293966.1 undecaprenyl-diphosphate phosphatase -
  PY824_RS01935 (PY824_01935) mecA 335506..336261 (+) 756 WP_093527953.1 adaptor protein MecA Regulator
  PY824_RS01940 (PY824_01940) - 336263..337426 (+) 1164 WP_014293968.1 glycosyltransferase family 4 protein -
  PY824_RS01945 (PY824_01945) sufC 337541..338311 (+) 771 WP_039670469.1 Fe-S cluster assembly ATPase SufC -
  PY824_RS01950 (PY824_01950) sufD 338385..339647 (+) 1263 WP_014293970.1 Fe-S cluster assembly protein SufD -
  PY824_RS01955 (PY824_01955) - 339649..340881 (+) 1233 WP_115265986.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 251 a.a.        Molecular weight: 28876.74 Da        Isoelectric Point: 4.0664

>NTDB_id=798031 PY824_RS01935 WP_093527953.1 335506..336261(+) (mecA) [Streptococcus macedonicus strain SGM CIP105683]
MEMKQISETTLKITISMEDLEERGMELKDFLIPQEKTEEFFYSIMDELDLPDNFKDSGMLSFRVTPRKDRIDVFVTKSEI
NKEINFEDLAAFDDVSNMSPEEFFKTLEQTMISKGDTEAHEKLGKIEEMMEGAVEEVLTEQVQAEPIEEDINPSDYVHYV
LDFPTLEAVVSFAKAIDFPVEASELYKDGGLYHMTILLDLQNHPSYYANLMYARLLEYASAGTKTRAYLQEHGVEMLADD
AVTKLKMIELI

Nucleotide


Download         Length: 756 bp        

>NTDB_id=798031 PY824_RS01935 WP_093527953.1 335506..336261(+) (mecA) [Streptococcus macedonicus strain SGM CIP105683]
ATGGAAATGAAACAGATTAGCGAGACAACGCTAAAAATAACGATTAGTATGGAAGATTTAGAAGAACGTGGCATGGAGTT
GAAAGACTTTTTGATTCCACAAGAAAAGACAGAAGAGTTCTTCTACTCAATAATGGACGAATTAGATTTACCAGATAATT
TCAAAGATAGTGGAATGCTTAGCTTTCGTGTAACGCCAAGAAAAGACCGTATTGATGTCTTTGTTACAAAATCTGAAATT
AATAAAGAAATTAACTTTGAAGATTTAGCTGCATTCGACGACGTGTCAAACATGTCACCTGAGGAATTTTTCAAAACATT
GGAACAAACAATGATTTCTAAAGGTGATACTGAGGCGCATGAAAAATTAGGAAAAATTGAAGAAATGATGGAAGGTGCTG
TTGAGGAAGTTCTCACAGAACAAGTTCAAGCAGAGCCAATAGAAGAGGATATTAATCCATCTGATTATGTTCATTATGTC
CTTGATTTTCCAACACTTGAAGCTGTCGTATCTTTTGCTAAAGCAATTGATTTTCCAGTTGAAGCATCAGAACTCTACAA
AGATGGTGGTCTTTACCACATGACCATTTTACTTGATTTGCAAAATCATCCGTCTTACTATGCGAATTTGATGTATGCTC
GTTTGTTGGAATATGCTAGCGCAGGTACAAAAACGCGTGCTTATTTGCAAGAGCACGGTGTTGAAATGTTAGCAGATGAC
GCTGTTACAAAATTAAAAATGATTGAGTTGATATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

67.339

98.805

0.665
  mecA Streptococcus thermophilus LMD-9

59.109

98.406

0.582
  mecA Streptococcus thermophilus LMG 18311

58.704

98.406

0.578
  mecA Streptococcus pneumoniae Rx1

48.617

100

0.49
  mecA Streptococcus pneumoniae D39

48.617

100

0.49
  mecA Streptococcus pneumoniae R6

48.617

100

0.49
  mecA Streptococcus pneumoniae TIGR4

48.617

100

0.49