Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   PYW32_RS02215 Genome accession   NZ_CP118957
Coordinates   403326..404615 (-) Length   429 a.a.
NCBI ID   WP_016175963.1    Uniprot ID   -
Organism   Enterococcus saccharolyticus subsp. saccharolyticus strain DSM 20726     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 398326..409615
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PYW32_RS02185 - 399469..399849 (-) 381 WP_016175969.1 PH domain-containing protein -
  PYW32_RS02190 - 399872..400210 (-) 339 WP_016175968.1 hypothetical protein -
  PYW32_RS02195 pepA 400340..401416 (+) 1077 WP_016175967.1 glutamyl aminopeptidase -
  PYW32_RS02200 - 401515..401826 (+) 312 WP_016175966.1 thioredoxin family protein -
  PYW32_RS02205 - 401851..402315 (+) 465 WP_016175965.1 universal stress protein -
  PYW32_RS02210 ytpR 402675..403286 (+) 612 WP_016175964.1 YtpR family tRNA-binding protein -
  PYW32_RS02215 htrA 403326..404615 (-) 1290 WP_016175963.1 S1C family serine protease Regulator
  PYW32_RS02220 rlmH 404853..405332 (+) 480 WP_016175962.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  PYW32_RS02225 - 405454..405681 (-) 228 Protein_410 transposase -
  PYW32_RS02230 - 405795..406703 (-) 909 WP_016175961.1 zinc ribbon domain-containing protein -
  PYW32_RS02235 - 406785..408482 (-) 1698 WP_016175960.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 429 a.a.        Molecular weight: 44610.51 Da        Isoelectric Point: 4.2954

>NTDB_id=796789 PYW32_RS02215 WP_016175963.1 403326..404615(-) (htrA) [Enterococcus saccharolyticus subsp. saccharolyticus strain DSM 20726]
MAKKNVTPRRTSNGVLKKFGIGLLGGVLGGMLSVGGFYYATGANEAASANEPLTSESTKDSTSDAQVSNVKVNVNSDITS
AVEKVQNSVVSIINLQASSSQSQWLNPFETQEESSSDLQPVGEGSGVIYKKDGKDAYVVTNNHVVDGQQGLEVVLTDGTK
VKAELIGSDAYTDLAVLKIASDKVDTVATFGDSDSLKVGEPAIAIGSPLGSDYANSVTQGIISSLNRLVTNTNESGQVIS
INAIQTDAAINPGNSGGPLINVAGQVIGINSSKIASSSGSGVSVEGMGFAIPSNDVTNIIEQLETKGEVTRPALGISMVD
LSSISTQQQEQILKVPSSVVNGVVVSSVGSATPAEKAGIQQYDVITKIDGKEISSGTELRSALYSKSVGDTIDVTFYRED
KEQTVKVELSVDQSIINNQNQTQSIQPQN

Nucleotide


Download         Length: 1290 bp        

>NTDB_id=796789 PYW32_RS02215 WP_016175963.1 403326..404615(-) (htrA) [Enterococcus saccharolyticus subsp. saccharolyticus strain DSM 20726]
ATGGCTAAAAAAAATGTCACACCACGCAGAACAAGTAATGGTGTCTTAAAAAAATTTGGTATTGGTTTACTAGGAGGCGT
TTTAGGCGGGATGCTAAGTGTCGGTGGTTTTTATTACGCCACTGGTGCAAACGAAGCAGCTTCTGCTAATGAACCACTTA
CTAGCGAAAGTACCAAAGATTCTACGAGCGATGCCCAAGTAAGCAACGTCAAAGTCAATGTGAATAGCGATATTACTTCC
GCTGTTGAAAAAGTCCAAAATTCAGTGGTATCTATCATTAATTTACAAGCAAGCTCTTCACAAAGTCAATGGTTAAATCC
TTTTGAAACACAAGAAGAAAGTAGTTCTGACCTACAACCAGTCGGTGAAGGTAGCGGTGTAATTTACAAAAAAGATGGGA
AAGATGCGTATGTCGTAACCAATAACCACGTGGTTGACGGACAACAAGGACTAGAAGTTGTCTTAACGGATGGTACTAAG
GTGAAAGCTGAATTAATTGGGTCTGATGCGTATACAGATTTAGCAGTCTTAAAAATCGCTTCTGATAAAGTTGATACTGT
AGCAACATTTGGTGATTCAGATTCATTAAAAGTTGGCGAACCAGCAATCGCGATTGGTTCTCCTTTAGGTTCTGATTATG
CTAACTCTGTTACACAAGGGATTATCTCTTCACTAAATCGTTTGGTAACTAACACTAACGAATCTGGACAAGTCATTAGT
ATTAATGCCATCCAAACCGATGCGGCGATTAATCCAGGGAACTCCGGTGGTCCATTAATTAACGTTGCTGGACAAGTTAT
CGGTATTAACTCAAGTAAAATTGCTAGCTCTTCTGGTTCCGGTGTCAGTGTTGAAGGAATGGGCTTTGCGATTCCAAGTA
ATGATGTAACAAATATCATTGAACAACTAGAAACAAAAGGTGAAGTCACTCGCCCAGCTTTAGGTATTTCAATGGTTGAT
TTGAGTAGTATTTCAACGCAACAACAAGAACAAATTCTAAAAGTACCATCTTCTGTCGTCAACGGTGTCGTCGTTTCTTC
TGTTGGTAGTGCTACTCCTGCAGAAAAAGCTGGTATCCAACAATATGACGTGATTACCAAAATTGATGGAAAAGAAATTA
GTAGCGGCACTGAATTACGCTCTGCTCTATATAGCAAATCTGTGGGTGATACTATTGACGTAACGTTCTATCGTGAAGAC
AAAGAACAAACAGTCAAAGTTGAGTTATCCGTTGACCAATCTATCATCAATAACCAAAATCAAACACAAAGTATTCAACC
ACAAAACTAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(124-269)

Peptidase family M50 (Peptidase_M50)

(282-411)

PDZ domain (PDZ_2)

(312-409)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

55.443

92.075

0.51
  htrA Streptococcus mitis NCTC 12261

54.692

86.946

0.476
  htrA Streptococcus gordonii str. Challis substr. CH1

52.051

90.909

0.473
  htrA Streptococcus pneumoniae TIGR4

58.434

77.389

0.452
  htrA Streptococcus pneumoniae D39

58.434

77.389

0.452
  htrA Streptococcus pneumoniae Rx1

58.434

77.389

0.452
  htrA Streptococcus pneumoniae R6

58.434

77.389

0.452