Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Machinery gene
Locus tag   HIY_RS03410 Genome accession   NZ_AP022867
Coordinates   655836..656633 (+) Length   265 a.a.
NCBI ID   WP_005656469.1    Uniprot ID   A0A0H3PE38
Organism   Haemophilus influenzae strain 2018-Y40     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 650836..661633
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HIY_RS03390 (HIY_06500) recR 651014..651616 (-) 603 WP_005656473.1 recombination mediator RecR -
  HIY_RS03395 (HIY_06510) - 651746..652075 (-) 330 WP_005629464.1 YbaB/EbfC family nucleoid-associated protein -
  HIY_RS03400 (HIY_06520) - 652228..653073 (-) 846 WP_005656472.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
  HIY_RS03405 (HIY_06530) - 653146..655740 (-) 2595 WP_005656471.1 penicillin-binding protein 1A -
  HIY_RS03410 (HIY_06540) comA 655836..656633 (+) 798 WP_005656469.1 pilus assembly protein PilM Machinery gene
  HIY_RS03415 (HIY_06550) comB 656634..657140 (+) 507 WP_005656467.1 competence protein ComB Machinery gene
  HIY_RS03420 (HIY_06560) comC 657137..657658 (+) 522 WP_005656465.1 competence protein ComC Machinery gene
  HIY_RS03425 (HIY_06570) comD 657655..658068 (+) 414 WP_005656464.1 pilus assembly protein PilP Machinery gene
  HIY_RS03430 (HIY_06580) comE 658078..659415 (+) 1338 WP_005659796.1 type IV pilus secretin PilQ family protein Machinery gene
  HIY_RS03435 (HIY_06590) - 659428..660114 (+) 687 WP_005656460.1 ComF family protein -
  HIY_RS03440 (HIY_06600) nfuA 660190..660786 (+) 597 WP_005656459.1 Fe-S biogenesis protein NfuA -

Sequence

Protein


Download         Length: 265 a.a.        Molecular weight: 31589.94 Da        Isoelectric Point: 6.2348

>NTDB_id=79558 HIY_RS03410 WP_005656469.1 655836..656633(+) (comA) [Haemophilus influenzae strain 2018-Y40]
MQFSLKNYRTLQIGIHRKQSYFDFVWFDDLEQPQSYQIFVNDRYFKNRFLQQLKTQYQGKTFPLQFVASIPAHLTWSKVL
MLPQVLNAQECHQQCKFVIEKELPIFLEELWFDYRSTPLKQGFRLEVTAIRKSTAQTYLQDFQPFKINVLDVASNAVLRA
FQYLLNEQARSENTLFLFQEDDYCLAICERSQQSQILQSHENLTALYEQFTERFEGQFEQVFVYQIPSSHTPLPENWQRV
ETELPFIALGNVLWQKDLHQQKVGG

Nucleotide


Download         Length: 798 bp        

>NTDB_id=79558 HIY_RS03410 WP_005656469.1 655836..656633(+) (comA) [Haemophilus influenzae strain 2018-Y40]
ATGCAATTCTCCCTGAAAAATTACCGCACTTTACAAATCGGCATTCATCGTAAGCAGAGTTATTTTGATTTTGTGTGGTT
TGATGATCTTGAACAGCCACAAAGTTATCAAATCTTTGTTAATGATCGTTATTTTAAAAATCGTTTTTTACAACAGCTAA
AAACACAATATCAAGGGAAAACCTTTCCTTTGCAGTTTGTAGCAAGCATTCCCGCCCACTTAACTTGGTCGAAAGTATTA
ATGTTGCCACAAGTGTTAAATGCACAAGAATGTCATCAACAATGTAAATTTGTGATTGAAAAAGAGCTGCCTATTTTTTT
AGAAGAATTGTGGTTTGATTATCGTTCTACCCCGTTAAAGCAAGGTTTTCGATTAGAGGTTACTGCAATTCGTAAAAGTA
CTGCTCAAACTTATTTGCAAGATTTTCAGCCATTTAAAATTAATGTATTGGATGTTGCGTCAAATGCTGTTTTGCGTGCA
TTTCAATATCTGTTGAATGAACAAGCGCGGTCAGAAAATACCTTATTTTTATTTCAAGAAGATGACTATTGCTTGGCGAT
TTGTGAAAGATCTCAGCAATCACAAATTTTACAATCTCACGAAAATTTGACCGCACTTTATGAACAATTTACCGAACGTT
TTGAAGGACAATTTGAACAAGTTTTTGTTTATCAAATTCCCTCAAGTCATACGCCATTACCAGAAAACTGGCAGAGAGTA
GAAACAGAACTCCCTTTTATTGCGCTTGGCAACGTGCTATGGCAAAAAGATTTACATCAACAAAAAGTGGGTGGTTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3PE38

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Haemophilus influenzae Rd KW20

97.736

100

0.977
  comA Haemophilus influenzae 86-028NP

96.226

100

0.962

Multiple sequence alignment