Detailed information NTG0795009

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: PWA41_RS12445
• Genome accession: NZ_CP118755
• Coordinates: 2560347..2561645 (+)
• Length: 432 a.a.
• NCBI ID: WP_338423494.1
• Uniprot ID: -
• Organism: Enterococcus faecalis strain W5
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2555347..2566645

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PWA41_RS12440 (PWA41_12440)	rlmH	2559467..2559946 (-)	480	WP_002355021.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
PWA41_RS12445 (PWA41_12445)	htrA	2560347..2561645 (+)	1299	WP_338423494.1	trypsin-like peptidase domain-containing protein	Regulator
PWA41_RS12450 (PWA41_12450)	ytpR	2561692..2562312 (-)	621	WP_002407823.1	YtpR family tRNA-binding protein	-
PWA41_RS12455 (PWA41_12455)	-	2562523..2562978 (-)	456	WP_002385249.1	universal stress protein	-
PWA41_RS12460 (PWA41_12460)	-	2563126..2563440 (-)	315	WP_002355015.1	thioredoxin family protein	-
PWA41_RS12465 (PWA41_12465)	pepA	2563452..2564528 (-)	1077	WP_002355013.1	glutamyl aminopeptidase	-
PWA41_RS12470 (PWA41_12470)	-	2564835..2565176 (+)	342	WP_002355012.1	PepSY domain-containing protein	-

Sequence

Protein

• Length: 432 a.a.
• Molecular weight: 44889.00 Da
• Isoelectric Point: 4.9968

>NTDB_id=795009 PWA41_RS12445 WP_338423494.1 2560347..2561645(+) (htrA) [Enterococcus faecalis strain W5]
MQRKDVTPNSDKKSLLQKFGIGLAGGLLGGALILGGAYSGIIPTPNGGNNAATTTSTNHGDTKVSNVSYNVSSDVTKAVK
KVQNSVVSVINMQSASNNSSADDPFGGLFGGNEGTQDSSGNNDNDLEAASEGSGVIYKKDGKTAYVVTNNHVVDKAQGLE
VVLSDGTKVKGELVGTDAYTDLAVIKISSDKVNQVAEFGNSSKITVGEPAIAIGSPLGSDYANSVTQGIISSVNRNITNK
NESGETININAIQTDAAINPGNSGGPLINIEGQVIGINSVKIVQSTSQVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPA
LGITMSDLTGISSQQQEQILKIPASVKTGVVVRGVEAATPAEKAGLEKYDVITKVDGQDVSSTTDLQSALYKKKVGDKME
VTYYRGSKEMKATIDLTIDKSALTQQNNRSNQ

Nucleotide

• Length: 1299 bp

>NTDB_id=795009 PWA41_RS12445 WP_338423494.1 2560347..2561645(+) (htrA) [Enterococcus faecalis strain W5]
ATGCAACGAAAAGATGTTACACCTAATTCAGATAAAAAAAGTTTATTGCAAAAATTTGGGATTGGTTTAGCTGGCGGCTT
ACTTGGTGGCGCTCTTATTCTAGGAGGCGCTTATTCTGGGATTATTCCCACACCCAACGGCGGAAATAATGCGGCGACGA
CGACGTCCACTAATCACGGCGACACAAAAGTCAGCAATGTGAGTTACAATGTTTCTAGCGATGTCACAAAAGCCGTGAAA
AAAGTTCAAAATTCTGTGGTTTCTGTCATTAATATGCAAAGTGCTAGCAACAATTCTTCGGCAGATGATCCTTTTGGGGG
ATTGTTCGGTGGGAATGAAGGTACTCAAGACTCTTCCGGCAACAATGATAACGATTTAGAAGCAGCCAGTGAAGGTAGTG
GGGTTATTTATAAGAAAGATGGTAAAACGGCTTATGTCGTGACAAATAACCACGTCGTAGATAAAGCGCAAGGATTGGAA
GTTGTTTTATCTGATGGTACCAAAGTGAAAGGCGAATTAGTCGGAACCGATGCTTACACGGATTTAGCCGTGATTAAAAT
TTCTTCTGACAAAGTTAATCAAGTCGCTGAGTTTGGGAATTCTAGTAAAATCACAGTCGGTGAGCCTGCTATTGCAATTG
GTTCCCCGCTAGGTTCTGATTATGCTAACTCTGTCACACAAGGAATCATCTCTTCTGTGAATAGAAATATTACCAATAAA
AATGAATCCGGTGAAACTATCAATATTAATGCCATTCAAACCGATGCTGCCATCAATCCAGGAAACTCTGGTGGTCCACT
AATCAATATTGAAGGACAAGTCATTGGAATTAACTCAGTAAAAATTGTGCAATCAACTAGTCAAGTGAGCGTTGAAGGGA
TGGGCTTTGCCATTCCAAGTAATGACGTAGTCAACATTATCAACCAATTAGAAAAAGATGGTAAAGTGACGCGGCCAGCT
CTCGGGATTACGATGTCTGATTTAACAGGTATCTCTTCACAACAACAAGAACAAATTTTAAAAATTCCAGCTTCTGTAAA
AACTGGCGTAGTGGTTCGTGGTGTTGAAGCAGCGACCCCTGCTGAAAAGGCTGGATTGGAAAAATACGATGTTATCACGA
AAGTTGACGGCCAAGACGTAAGCTCTACTACAGATTTACAAAGCGCGCTTTACAAGAAAAAAGTTGGCGACAAAATGGAA
GTGACTTATTATCGTGGTTCTAAAGAAATGAAAGCAACCATCGATTTAACCATTGATAAATCAGCTTTAACACAACAAAA
TAATCGCAGCAATCAATAA

Domains

Predicted by InterproScan.

• Peptidase family M50 (Peptidase_M50) (9-416)

• PDZ domain (PDZ_2) (319-416)

• Trypsin-like peptidase domain (Trypsin_2) (132-277)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus gordonii str. Challis substr. CH1	52.683	94.907	0.5
htrA	Streptococcus mutans UA159	58.516	84.259	0.493
htrA	Streptococcus mitis NCTC 12261	55.135	85.648	0.472
htrA	Streptococcus pneumoniae TIGR4	55.807	81.713	0.456
htrA	Streptococcus pneumoniae Rx1	55.807	81.713	0.456
htrA	Streptococcus pneumoniae D39	55.807	81.713	0.456
htrA	Streptococcus pneumoniae R6	55.807	81.713	0.456