Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   PW252_RS09610 Genome accession   NZ_CP118735
Coordinates   1973488..1974210 (-) Length   240 a.a.
NCBI ID   WP_248049898.1    Uniprot ID   A0AA96VKU8
Organism   Streptococcus iners strain 29887     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1968488..1979210
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PW252_RS09585 (PW252_09590) sufU 1968518..1968958 (-) 441 WP_248049891.1 Fe-S cluster assembly sulfur transfer protein SufU -
  PW252_RS09590 (PW252_09595) - 1968945..1970168 (-) 1224 WP_248049893.1 cysteine desulfurase -
  PW252_RS09595 (PW252_09600) sufD 1970172..1971434 (-) 1263 WP_248049895.1 Fe-S cluster assembly protein SufD -
  PW252_RS09600 (PW252_09605) sufC 1971451..1972224 (-) 774 WP_024376584.1 Fe-S cluster assembly ATPase SufC -
  PW252_RS09605 (PW252_09610) - 1972304..1973491 (-) 1188 WP_248049896.1 glycosyltransferase family 4 protein -
  PW252_RS09610 (PW252_09615) mecA 1973488..1974210 (-) 723 WP_248049898.1 adaptor protein MecA Regulator
  PW252_RS09615 (PW252_09620) - 1974336..1975172 (-) 837 WP_248049900.1 undecaprenyl-diphosphate phosphatase -
  PW252_RS09620 (PW252_09625) - 1975455..1976657 (+) 1203 WP_316716734.1 IS110 family transposase -
  PW252_RS09625 (PW252_09630) - 1976923..1978488 (+) 1566 WP_398582945.1 ABC transporter substrate-binding protein/permease -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 28080.72 Da        Isoelectric Point: 4.0722

>NTDB_id=794754 PW252_RS09610 WP_248049898.1 1973488..1974210(-) (mecA) [Streptococcus iners strain 29887]
MKVKQISDSTLKITIKMDDLEERGMELADFLIPQEKTEEFFYTVLDELELPLTFRESGMLSFRVTPKPDRVDIFVTKSDL
DQNLNFDEFSDLSDFGDISSMSPDEFFKNLEQTARERSSKDMDAVRHLEEVEKAEEAEESEPEDYIYYILDFPNMDELMA
FVGTVDYPIEESELYKMDGHYYMTVLINIEERSKRYPDYLLARMLEFANDTKLTRPVLQEHGVTLLPVAALEELRKVSLL

Nucleotide


Download         Length: 723 bp        

>NTDB_id=794754 PW252_RS09610 WP_248049898.1 1973488..1974210(-) (mecA) [Streptococcus iners strain 29887]
ATGAAAGTAAAACAAATTAGTGATTCGACCTTGAAAATCACTATAAAAATGGATGATTTAGAAGAAAGAGGGATGGAGCT
GGCTGACTTCCTCATTCCTCAAGAAAAGACAGAAGAATTTTTCTATACCGTCTTGGACGAATTAGAATTGCCTTTAACCT
TCCGTGAAAGCGGAATGTTAAGTTTTCGTGTCACTCCTAAACCAGATCGGGTGGATATTTTTGTAACCAAGTCTGACTTA
GATCAGAATTTGAATTTTGATGAGTTTTCTGACTTGTCGGATTTTGGTGATATTTCCAGCATGAGCCCGGATGAATTTTT
CAAGAATTTGGAGCAGACTGCTCGAGAGCGAAGCAGTAAGGATATGGATGCTGTTCGTCATTTGGAAGAAGTTGAGAAAG
CAGAAGAAGCTGAAGAGAGTGAGCCAGAAGACTACATCTACTACATCCTTGATTTTCCTAACATGGATGAACTGATGGCT
TTTGTAGGAACAGTAGATTACCCTATCGAAGAGTCAGAGCTCTATAAGATGGACGGCCATTACTATATGACTGTCTTGAT
CAATATCGAGGAACGTTCTAAGCGTTACCCTGACTATCTTCTAGCGCGTATGTTGGAATTTGCCAATGATACTAAGTTGA
CTAGACCTGTCTTGCAGGAACATGGGGTGACCCTCTTGCCAGTTGCAGCCCTAGAGGAACTTAGGAAGGTTTCCTTGCTA
TGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

55.51

100

0.567
  mecA Streptococcus pneumoniae Rx1

54.694

100

0.558
  mecA Streptococcus pneumoniae D39

54.694

100

0.558
  mecA Streptococcus pneumoniae R6

54.694

100

0.558
  mecA Streptococcus pneumoniae TIGR4

54.694

100

0.558
  mecA Streptococcus thermophilus LMD-9

50.204

100

0.512
  mecA Streptococcus thermophilus LMG 18311

49.796

100

0.508