Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   PW220_RS01590 Genome accession   NZ_CP118734
Coordinates   294430..295152 (+) Length   240 a.a.
NCBI ID   WP_172084504.1    Uniprot ID   A0AA97A194
Organism   Streptococcus iners subsp. hyiners strain 29892     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 289430..300152
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PW220_RS01565 (PW220_01565) - 289738..290643 (+) 906 WP_248050480.1 SPFH domain-containing protein -
  PW220_RS01570 (PW220_01570) - 290727..290936 (+) 210 WP_009910800.1 hypothetical protein -
  PW220_RS01575 (PW220_01575) - 291039..291782 (-) 744 WP_248033052.1 amino acid ABC transporter ATP-binding protein -
  PW220_RS01580 (PW220_01580) - 291775..293340 (-) 1566 WP_248054953.1 ABC transporter substrate-binding protein/permease -
  PW220_RS01585 (PW220_01585) - 293468..294304 (+) 837 WP_248054952.1 undecaprenyl-diphosphate phosphatase -
  PW220_RS01590 (PW220_01590) mecA 294430..295152 (+) 723 WP_172084504.1 adaptor protein MecA Regulator
  PW220_RS01595 (PW220_01595) - 295149..296336 (+) 1188 WP_172084501.1 glycosyltransferase family 4 protein -
  PW220_RS01600 (PW220_01600) sufC 296416..297189 (+) 774 WP_024376584.1 Fe-S cluster assembly ATPase SufC -
  PW220_RS01605 (PW220_01605) sufD 297206..298468 (+) 1263 WP_248054951.1 Fe-S cluster assembly protein SufD -
  PW220_RS01610 (PW220_01610) - 298472..299695 (+) 1224 WP_248054950.1 cysteine desulfurase -
  PW220_RS01615 (PW220_01615) sufU 299682..300122 (+) 441 WP_248054949.1 Fe-S cluster assembly sulfur transfer protein SufU -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 27935.56 Da        Isoelectric Point: 4.0556

>NTDB_id=794673 PW220_RS01590 WP_172084504.1 294430..295152(+) (mecA) [Streptococcus iners subsp. hyiners strain 29892]
MKVKQISDSTLKITIQMDDLEERGMELADFLIPQEKTEDFFYTVLDELELPLTFRESGMLSFRVTPKPDRVDIFVTKSDL
DQNLNFDEFADLSDLGDVSSMSPDEFFKSLEQTVRERSSKDMDAVRHLEEVEKAEEAEESESEGYIYYILDFPNMDELMA
FVGTVDYPIEESELYKMDGHYYMTVLINIEERSKRYPDYLLARMLEFANDTKLTRPVLQEHGVTLLPVAALEELRKVSLL

Nucleotide


Download         Length: 723 bp        

>NTDB_id=794673 PW220_RS01590 WP_172084504.1 294430..295152(+) (mecA) [Streptococcus iners subsp. hyiners strain 29892]
ATGAAAGTAAAACAAATTAGTGATTCAACCTTGAAAATCACTATTCAAATGGATGATTTGGAAGAGAGAGGGATGGAATT
GGCCGACTTCTTAATTCCACAAGAAAAGACAGAGGATTTTTTCTATACAGTTTTGGATGAATTAGAGTTGCCCTTAACCT
TCCGTGAAAGTGGTATGCTTAGTTTTCGTGTGACTCCTAAGCCAGATCGGGTGGATATTTTTGTGACCAAGTCGGACTTG
GATCAGAATTTGAATTTTGACGAGTTCGCAGATTTGTCTGATTTAGGGGATGTTTCAAGCATGAGTCCAGATGAGTTTTT
TAAGAGCTTGGAGCAGACAGTTCGGGAAAGAAGTAGCAAAGATATGGATGCGGTTCGTCATTTGGAAGAAGTTGAAAAAG
CTGAAGAAGCTGAGGAGAGCGAGTCAGAAGGCTACATCTACTATATCCTTGATTTTCCTAACATGGATGAACTGATGGCT
TTTGTAGGAACAGTAGATTACCCTATCGAAGAGTCAGAGCTCTATAAGATGGACGGTCATTACTATATGACTGTCTTGAT
CAATATCGAGGAACGTTCTAAGCGTTACCCGGACTATCTTTTGGCGCGTATGTTGGAATTTGCCAATGATACTAAGTTGA
CTAGACCTGTCTTACAGGAACATGGGGTGACCCTCTTGCCAGTTGCAGCCCTAGAGGAACTTAGGAAGGTTTCCTTGCTA
TGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae R6

53.878

100

0.55
  mecA Streptococcus pneumoniae Rx1

53.878

100

0.55
  mecA Streptococcus pneumoniae D39

53.878

100

0.55
  mecA Streptococcus pneumoniae TIGR4

53.878

100

0.55
  mecA Streptococcus mutans UA159

53.469

100

0.546
  mecA Streptococcus thermophilus LMD-9

49.388

100

0.504
  mecA Streptococcus thermophilus LMG 18311

48.98

100

0.5