Detailed information NTG0794635

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: PXH68_RS06225
• Genome accession: NZ_CP118733
• Coordinates: 1336375..1338612 (-)
• Length: 745 a.a.
• NCBI ID: WP_248028492.1
• Uniprot ID: A0AA97A0A0
• Organism: Streptococcus suivaginalis strain 29896
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1331375..1343612

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PXH68_RS06215 (PXH68_06215)	-	1334396..1335025 (-)	630	WP_248028490.1	Maf family protein	-
PXH68_RS06220 (PXH68_06220)	-	1335146..1336081 (-)	936	WP_248028491.1	hypothetical protein	-
PXH68_RS06225 (PXH68_06225)	comEC/celB	1336375..1338612 (-)	2238	WP_248028492.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
PXH68_RS06230 (PXH68_06230)	comEA/celA/cilE	1338596..1339258 (-)	663	WP_248028493.1	helix-hairpin-helix domain-containing protein	Machinery gene
PXH68_RS06235 (PXH68_06235)	-	1339325..1340071 (-)	747	WP_248028494.1	lysophospholipid acyltransferase family protein	-
PXH68_RS06240	-	1340237..1340382 (+)	146	Protein_1201	putative holin-like toxin	-
PXH68_RS06245 (PXH68_06245)	-	1340546..1341295 (+)	750	WP_248028495.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
PXH68_RS06250 (PXH68_06250)	-	1341285..1341557 (+)	273	WP_248028496.1	GIY-YIG nuclease family protein	-
PXH68_RS06255 (PXH68_06255)	-	1341572..1342183 (-)	612	WP_248028497.1	FMN-dependent NADH-azoreductase	-
PXH68_RS06260 (PXH68_06260)	-	1342303..1342713 (-)	411	WP_248028498.1	GNAT family N-acetyltransferase	-

Sequence

Protein

• Length: 745 a.a.
• Molecular weight: 83665.26 Da
• Isoelectric Point: 6.8219

>NTDB_id=794635 PXH68_RS06225 WP_248028492.1 1336375..1338612(-) (comEC/celB) [Streptococcus suivaginalis strain 29896]
MSQLSKLPCQPIHLAVLAVAAYFAVHSFSLLTMGLLSLLLAVFGVRQGKAVFIRTLPLLALCGLFFGCQKVQSERTAQSA
QEQVATVQVIPDTIDINGDSLSFRGRADGQTYQVFYKFASQEEQAYFQQLTGLVQIEVEAEVSLPAGQRNFNGFDYRAYL
KTQGIYRTVKLTAIKKIAPVQSWNIFDWLSSWRRQALVYIKTNFPAPMSHYMTGLLFGDLDSEFDQMSDLYSSLGIIHLF
ALSGMQVGYFIDKFRWILLRLGLTKETVDKLQIPFSLVYAGLTGFSVSVVRSLVQKILGNMGLRKLDNFAVTVFVCLLVL
PRFLLTAGGVLTFTYAFLLTVFDFEDLGQIKKAAVESLSISLGILPVLMTYFYAFQPLSILLTVVFSFIFDVLLLPGLSV
IFLLSPLVKITWVNEFFVFMEKIIVWVADLGFRPWILGKPSGLVLLLLLVSLFMLYDFHRKKKWLLGLSLALALLFFITK
HPLENEVTVVDIGQGDSIFLRDMRGRTVLIDVGGRVDFVAKEAWQERSSQANAERTLIPYLHSRGVDRIDSLALTHTDTD
HVGDVLEVAKQVQIGRIYVSPGSLTVPDFVATLKEINVPVHAVAVGDRLPIFDSYLEVLYPDGTGDGGNNDSIVLYGRLL
ETNFLFTGDLEHGELDLIETYPNLPVDVLKAGHHGSKGSSYPEFLDHIGVKIALVSAGENNRYKHPHQETLDRFDSRNIQ
VYRTDQQGAIRFRGWKEWRIETVRE

Nucleotide

• Length: 2238 bp

>NTDB_id=794635 PXH68_RS06225 WP_248028492.1 1336375..1338612(-) (comEC/celB) [Streptococcus suivaginalis strain 29896]
ATGTCACAGTTGAGTAAGCTCCCCTGCCAGCCCATTCACCTGGCAGTTTTGGCGGTGGCGGCCTACTTTGCAGTCCACTC
TTTTTCCCTCTTGACAATGGGCCTGCTGAGTTTGTTGCTAGCTGTCTTTGGGGTTCGGCAAGGTAAGGCAGTTTTCATCA
GAACGCTTCCGCTTCTAGCCCTGTGCGGTCTGTTTTTTGGATGCCAGAAGGTCCAATCGGAGCGGACAGCCCAGTCAGCC
CAAGAGCAAGTAGCGACTGTGCAGGTTATTCCCGATACCATAGACATCAATGGTGACAGCTTGTCTTTTCGTGGTCGGGC
TGACGGACAAACCTATCAGGTTTTCTACAAATTTGCCAGTCAGGAGGAGCAGGCTTATTTTCAACAGCTGACAGGTCTGG
TCCAGATAGAAGTGGAAGCAGAGGTCAGCCTGCCAGCTGGTCAGCGGAATTTCAACGGCTTTGACTATCGGGCCTATCTG
AAAACACAGGGCATCTATCGGACTGTCAAGCTAACAGCGATTAAGAAGATTGCCCCTGTCCAGTCTTGGAATATTTTTGA
CTGGCTATCAAGCTGGCGGAGACAGGCCTTAGTCTATATCAAAACCAATTTTCCAGCCCCCATGAGCCACTACATGACAG
GGCTCTTGTTTGGGGACTTGGATAGTGAGTTTGACCAGATGAGCGACCTCTATTCTAGTTTAGGTATCATTCATCTTTTT
GCCCTGTCTGGTATGCAGGTGGGCTATTTCATCGACAAGTTTCGCTGGATTTTGTTGCGTCTGGGTTTGACCAAGGAAAC
GGTGGATAAATTGCAGATACCCTTTTCCCTTGTCTATGCTGGTTTGACAGGCTTTTCGGTGTCAGTGGTGCGGTCCTTGG
TCCAAAAAATTCTGGGCAATATGGGCTTGCGGAAGCTGGATAATTTTGCGGTGACGGTCTTTGTCTGTCTGCTGGTGCTG
CCTCGATTTTTACTGACGGCAGGAGGAGTGCTGACTTTTACCTACGCTTTCTTGCTTACGGTCTTTGATTTTGAGGACTT
GGGGCAGATCAAAAAGGCTGCGGTGGAAAGTCTCAGTATTTCGCTGGGGATTCTACCTGTGCTCATGACCTATTTCTATG
CCTTTCAGCCCTTGTCTATCCTCTTGACCGTTGTCTTTTCCTTTATCTTTGATGTCCTGCTTTTGCCAGGTTTGTCAGTC
ATTTTTCTTCTGTCACCTCTGGTCAAGATAACTTGGGTCAACGAATTTTTCGTTTTTATGGAGAAAATCATTGTCTGGGT
GGCGGATTTGGGCTTTCGGCCTTGGATACTGGGCAAGCCGTCTGGGCTGGTTCTCTTGCTTTTGCTGGTCAGCCTCTTCA
TGCTTTACGATTTTCACAGGAAGAAAAAATGGCTCTTAGGACTGAGCCTGGCCCTCGCTCTGCTATTTTTCATAACCAAA
CATCCTCTGGAAAATGAGGTGACGGTGGTGGACATCGGGCAGGGGGACAGCATCTTTTTGCGGGATATGCGGGGGCGGAC
GGTCCTGATTGATGTGGGCGGACGGGTCGATTTTGTGGCTAAAGAAGCTTGGCAGGAGCGGTCTTCGCAGGCAAATGCAG
AGCGGACCTTGATTCCTTATCTGCATAGTCGGGGTGTGGATAGGATTGATAGTTTGGCCCTGACCCATACCGATACGGAC
CATGTGGGCGATGTGCTGGAGGTGGCGAAGCAGGTCCAGATTGGTCGGATTTACGTGTCGCCAGGAAGCCTGACGGTGCC
TGACTTTGTAGCCACCTTGAAAGAAATCAATGTCCCTGTTCATGCGGTGGCGGTGGGCGACCGCTTGCCGATTTTTGACT
CCTATCTGGAAGTCCTCTATCCAGATGGGACAGGGGACGGTGGCAATAATGACTCTATTGTCCTTTATGGTCGTTTATTG
GAAACTAATTTTCTCTTCACAGGGGACTTGGAGCACGGGGAGCTGGACTTGATAGAAACCTATCCCAACCTGCCTGTCGA
TGTCCTCAAGGCTGGTCACCATGGCTCCAAAGGGTCCTCCTATCCTGAGTTTCTAGACCATATCGGAGTCAAGATTGCCC
TGGTATCAGCAGGAGAAAACAACCGCTACAAGCATCCTCACCAAGAAACCTTGGACCGCTTTGACAGTCGAAATATCCAA
GTCTATCGCACCGACCAGCAAGGAGCTATCCGCTTCCGAGGTTGGAAAGAGTGGAGGATTGAGACGGTGAGGGAATGA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (493-698)

• Competence protein (Competence) (215-460)

• Domain of unknown function (DUF4131) (DUF4131) (30-175)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	53.395	100	0.538
comEC/celB	Streptococcus mitis NCTC 12261	53.117	99.06	0.526
comEC/celB	Streptococcus pneumoniae TIGR4	52.233	99.195	0.518
comEC/celB	Streptococcus pneumoniae Rx1	51.962	99.195	0.515
comEC/celB	Streptococcus pneumoniae D39	51.962	99.195	0.515
comEC/celB	Streptococcus pneumoniae R6	51.962	99.195	0.515
comEC	Lactococcus lactis subsp. cremoris KW2	47.537	100	0.479